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'Epigenetic fingerprints' of prenatal alcohol exposure could be biomarkers to detect developmental disorders

Alcohol exposure in early pregnancy can change gene function during the tightly regulated embryonic development, and consequently cause developmental disorders - especially neurodevelopmental disorders.

3 Jan 2023

Insulin-like peptide 3 may be a predictor of hypogonadism and age-associated morbidity in older males

Researchers evaluated whether insulin-like peptide 3 (INSL3) could predict hypogonadism and age-associated morbidity in older males.

3 Jan 2023

BA.4/BA.5 mutations reduced responsiveness of epitope-specific T cells with original mRNA vaccine

A new study in the journal Viruses examines the phenomenon of breakthrough infections due to the evasion of T-cell immunity by the Omicron BA.4/BA.5 subvariants, showing this to be due to spike gene mutations.

2 Jan 2023

Underlying genetic cause for MIS-C complications after COVID-19 identified

A recent Science journal study determined the underlying cause of MIS-C related to SARS-CoV-2 in some children. It hypothesized that monogenic inborn errors of immunity (IEI) is the primary reason for this condition. Identifying these inborn errors is expected to help elucidate the disease's cellular, molecular, and immunological basis.

2 Jan 2023

Mouse study identifies potential targets for treating dry eye disease and corneal injury

People with a condition known as dry eye disease are more likely than those with healthy eyes to suffer injuries to their corneas.

2 Jan 2023

Researchers use engineered proteins to record histories of cellular events

As cells perform their everyday functions, they turn on a variety of genes and cellular pathways. MIT engineers have now coaxed cells to inscribe the history of these events in a long protein chain that can be imaged using a light microscope.

2 Jan 2023

New method records gene activity patterns and presence of proteins across tissues

A new method can illuminate the identities and activities of cells throughout an organ or a tumor at unprecedented resolution, according to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center.

2 Jan 2023

Study demonstrates the benefits of vaccination and boosting in reducing COVID-19 transmission

Vaccination and boosting, especially when recent, helped to limit the spread of COVID-19 in California prisons during the first Omicron wave, according to an analysis by researchers at UC San Francisco that examined transmission between people living in the same cell.

2 Jan 2023

Novel approach may prevent antibodies from triggering immune rejection of transplant cells

Researchers at UCSF have developed a novel, potentially life-saving approach that may prevent antibodies from triggering immune rejection of engineered therapeutic and transplant cells.

2 Jan 2023

Novel experimental approach slows physical decline and extends the lives of roundworms

Scientists in aging research today report a novel experimental approach that slowed the rate of physical decline and lengthened the lives of roundworms commonly used in biological studies, C. elgans.

30 Dec 2022

UKB resident awarded the C. E. Alken Prize for outstanding scientific uro-oncological research

Dr. Niklas Klümper, resident at the Clinic for Urology and working group leader at the Institute for Experimental Oncology at the University Hospital Bonn (UKB), was awarded the C. E. Alken Prize in recognition of his outstanding scientific uro-oncological work.

30 Dec 2022

New insights on the circadian clock of Drosophila melanogaster

The higher the temperatures, the faster physiological processes are. But there is an exception: the so-called circadian clock, which regulates the sleep-wake cycle in organisms.

30 Dec 2022

New insights into how working memory information may be held in mind

Between the time you read the Wi-Fi password off the café's menu board and the time you can get back to your laptop to enter it, you have to hold it in mind.

29 Dec 2022

Human cortical organoids implanted in mice establish functional connectivity and respond to sensory stimuli

A team of engineers and neuroscientists has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals' cortex and responded to external sensory stimuli.

29 Dec 2022

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Researchers used a multi-omics approach to profile the gut microbiomes and metabolomes of mothers and infants to determine the vertical and horizontal transmission of bacterial species and strains as well as individual genes and understand the dynamics of the gut microbiome assembly that shape the development of the infant before and after birth.

29 Dec 2022

Cell News and Research

'Epigenetic fingerprints' of prenatal alcohol exposure could be biomarkers to detect developmental disorders

Insulin-like peptide 3 may be a predictor of hypogonadism and age-associated morbidity in older males

BA.4/BA.5 mutations reduced responsiveness of epitope-specific T cells with original mRNA vaccine

Underlying genetic cause for MIS-C complications after COVID-19 identified

Mouse study identifies potential targets for treating dry eye disease and corneal injury

Researchers use engineered proteins to record histories of cellular events

New method records gene activity patterns and presence of proteins across tissues

Study demonstrates the benefits of vaccination and boosting in reducing COVID-19 transmission

Novel approach may prevent antibodies from triggering immune rejection of transplant cells

Novel experimental approach slows physical decline and extends the lives of roundworms

UKB resident awarded the C. E. Alken Prize for outstanding scientific uro-oncological research

New insights on the circadian clock of Drosophila melanogaster

New insights into how working memory information may be held in mind

Human cortical organoids implanted in mice establish functional connectivity and respond to sensory stimuli

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Study investigates a new mechanism of pyrethroid derivatives-moderated programmed cell death

Unraveling the biology of senescent cells and healthy aging

Sarunashi juice and its constituting component help prevent and reduce lung cancer in mice

Researchers unravel how cells use their sense of touch to make decisions during embryogenesis

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

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