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Targeted therapy for children with high-risk Hodgkin lymphoma reduces relapse rates, trial shows

A targeted therapy for children with high-risk Hodgkin lymphoma (HL) was shown to significantly reduce relapse rates when tested in a large multicenter clinical trial conducted by the Children's Oncology Group (COG) and led by pediatric oncologists at Roswell Park Comprehensive Cancer Center, Children's Healthcare of Atlanta and Winship Cancer Institute of Emory University. By combining the targeted antibody-drug conjugate (ADC) brentuximab vedotin (BV) with the standard chemotherapy regimen, children were 10% less likely to relapse.

2 Nov 2022

Moderate to heavy drinking could increase the risk of stroke in young adults

People in their 20s and 30s who drink moderate to heavy amounts of alcohol may be more likely to have a stroke as young adults than people who drink low amounts or no alcohol, according to a study published in the November 2, 2022, online issue of Neurology, the medical journal of the American Academy of Neurology.

2 Nov 2022

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

A type of dietary fiber called inulin, commonly used in health supplements and known to have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, and other parts of the body, according to a preclinical study from researchers in the Friedman Center for Nutrition and Inflammation and Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine and in the Boyce Thompson Institute on Cornell's Ithaca campus.

2 Nov 2022

Study provides new set of targets for drug therapies to combat chronic inflammatory diseases

Innate lymphoid cells are a recently discovered family of white blood cells that reside in the skin, gastrointestinal tract, airways and other barrier tissues of the body.

2 Nov 2022

Ohio State researchers enter federal cooperative agreement to develop radiation biodosimetry solutions

Researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) have entered a federal cooperative agreement, valued up to $9.42 million, that will help them further develop Ohio State's biodosimetry technology to discover noninvasive biomarkers for radiation exposure – work that will have national security applications.

2 Nov 2022

Researchers corroborate the importance of exercise for cognitive function

Accumulating evidence finds that exercise can improve brain function and delay or prevent the onset of neurodegenerative diseases such as Alzheimer's and Parkinson's disease.

2 Nov 2022

Contrastive learning model can detect lung damage in long-COVID patients

For patients dealing with lingering respiratory symptoms from the novel coronavirus, a chest X-ray can reveal only so much.

2 Nov 2022

Researchers identify new therapeutic approach against treatment-resistant prostate cancer

Investigators from Cedars-Sinai Cancer have identified an investigational therapeutic approach that could be effective against treatment-resistant prostate cancer. Results of their Phase II clinical trial, published in the peer-reviewed journal Molecular Therapy, have led to a larger, multicenter trial that will soon be underway.

2 Nov 2022

Higher viscosity of extracellular fluid enhances cancer dissemination

New research findings show how higher viscosity, or resistance to flow, of the extracellular fluid that surrounds cells enables cancer cells to migrate more rapidly from a primary tumor to other sites in the body.

2 Nov 2022

UC researchers receive NIH grant to study how alcohol, fentanyl affect HIV medications

The United States has set a goal of reducing the number of new HIV infections by 75% by 2025 and by at least 90% by 2030, mirroring the United Nations' initiative to end the AIDS epidemic as a global health threat by 2030.

2 Nov 2022

Personalized approach to kidney disease screening for T1D patients could enable earlier disease detection

Taking a personalized approach to kidney disease screening for people with type 1 diabetes (T1D) may reduce the time that chronic kidney disease goes undetected, according to a new analysis performed by the Epidemiology of Diabetes Interventions and Complications study group, which is funded by the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health.

2 Nov 2022

Molecular drug transporters could improve treatment of cancers and other diseases

A team of Canadian researchers from Université de Montréal has designed and validated a new class of drug transporters made of DNA that are 20,000 times smaller than a human hair and that could improve how cancers and other diseases are treated.

2 Nov 2022

The acute and chronic impact of pod-based e-cigarettes on vascular health

Researchers evaluated the impact of PEC [pod-based electronic (e)-cigarette] usage on cardiovascular (CVS) health under the agenesis of the AHA’s TCORS (tobacco center for regulatory science) group.

2 Nov 2022

NIH awards $2.1 million grant to UMass Amherst epidemiologist

A University of Massachusetts Amherst epidemiologist has been awarded a five-year, $2.1 million grant from the National Institutes of Health (NIH) to continue research that aims to understand how physical and mental health during pregnancy can help predict cardiovascular and mental health disorders in middle age.

2 Nov 2022

Obesity management likely to improve the clinical outcome of MS

Carrying far too much weight when diagnosed with MS (multiple sclerosis) is linked to higher current and subsequent levels of disability within a relatively short period of time, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

2 Nov 2022

Sophisticated tool helps measure exposure levels to PFAS

A novel metric that estimates our "burden," or cumulative exposure, to a family of thousands of synthetic chemicals that we encounter in everyday life with potentially adverse health impacts, has been created by a team of researchers at Mount Sinai.

2 Nov 2022

Vaginal progesterone may not be effective for preventing preterm births

Vaginal progesterone, a hormone treatment considered the standard of care for preventing preterm birth in at-risk pregnant women, may not be effective, according to UT Southwestern Medical Center researchers.

1 Nov 2022

Study identifies a root cause of chronic heart failure following a heart attack

A multi-institution study led by Rohan Dharmakumar, PhD, of Indiana University School of Medicine, has identified that iron drives the formation of fatty tissue in the heart and leads to chronic heart failure in about fifty percent of heart attack survivors.

1 Nov 2022

Vaping nicotine damages blood vessels, raises blood pressure and heart rate

A recent study soon to be presented at the American Heart Association (AHA) Scientific Sessions 2022* assessed the impact of nicotine-containing products on cardiovascular and autonomic functions.

1 Nov 2022

New research lays the foundation for more effectively treating pediatric brain tumor

In a ground-breaking new study, scientists have uncovered the mechanics of the blood-tumor barrier, one of the most significant obstacles to improving treatment efficacy and preventing the return of cancerous cells.

1 Nov 2022

Blood News and Research

Targeted therapy for children with high-risk Hodgkin lymphoma reduces relapse rates, trial shows

Moderate to heavy drinking could increase the risk of stroke in young adults

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

Study provides new set of targets for drug therapies to combat chronic inflammatory diseases

Ohio State researchers enter federal cooperative agreement to develop radiation biodosimetry solutions

Researchers corroborate the importance of exercise for cognitive function

Contrastive learning model can detect lung damage in long-COVID patients

Researchers identify new therapeutic approach against treatment-resistant prostate cancer

Higher viscosity of extracellular fluid enhances cancer dissemination

UC researchers receive NIH grant to study how alcohol, fentanyl affect HIV medications

Personalized approach to kidney disease screening for T1D patients could enable earlier disease detection

Molecular drug transporters could improve treatment of cancers and other diseases

The acute and chronic impact of pod-based e-cigarettes on vascular health

NIH awards $2.1 million grant to UMass Amherst epidemiologist

Obesity management likely to improve the clinical outcome of MS

Sophisticated tool helps measure exposure levels to PFAS

Vaginal progesterone may not be effective for preventing preterm births

Study identifies a root cause of chronic heart failure following a heart attack

Vaping nicotine damages blood vessels, raises blood pressure and heart rate

New research lays the foundation for more effectively treating pediatric brain tumor

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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