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Novel coronavirus targets specific secretory cells in the lungs

Viruses attack specific host cells, which can cause chaos in the body. The novel coronavirus, now called severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 for short, infects respiratory epithelial cells in the lining of the lung, causing difficulty of breathing. The usual cause of death of those who contract the virus is pneumonia and acute respiratory distress syndrome (ARDS). Now, a new study has found that SARS-CoV-2 specifically attack certain progenitor cells called bronchial transient secretory cells in the lungs.

9 Apr 2020

Ai used to detect COVID-19 pneumonia

Coronaviruses have 'spilled over' to human populations throughout history, causing respiratory illnesses, often associated with pneumonia. The severe acute respiratory syndrome (SARS), which emerged in 2002 in China, and the Middle East Respiratory Syndrome (MERS), which was first seen in Saudi Arabia in 2012, are similar to the current global pandemic spreading worldwide, the coronavirus disease (COVID-19).

9 Apr 2020

PIV5-based MERS vaccine shows promise for COVID-19

The coronavirus disease (COVID-19) has spread to 184 countries and territories. Currently, there is no vaccine available for COVID-19 disease, or SARS-CoV-2 infection. However, scientists around the world are racing to find ways to block the virus.

8 Apr 2020

More than half of COVID-19 patients in Brazil came from Italy

Italy has grappled with the coronavirus disease (COVID-19), with more than 139,000 people infected and more than 17,000 people dead. In the first week of March, the number of cases in Italy skyrocketed before the lockdown was set in place. Prior to the country shutting down its border, many people had already left, flocking to other countries in an attempt to escape the virus.

8 Apr 2020

Modifiable risk factors could play important role in Alzheimer's disease, study finds

Amyloid is a key feature of Alzheimer's disease, but the accumulation of these sticky proteins may not be the only risk factor for developing Alzheimer's disease, according to a new study published this week.

8 Apr 2020

Ebola drug now being tested against COVID-19

As the coronavirus pandemic claims lives and overwhelms health care systems throughout the world, scientists are closely watching several late-stage trials of the antiviral drug remdesivir.

8 Apr 2020

Infectious diseases from animals likely to cause further pandemics

As humans move to cities to settle, there is a sharp decline in biodiversity leading to several disturbances in the balance and relationship between humans and wild animals. A new study from researchers at the University of California, Davis' One Health Institute, shows that this has led to the spread of zoonotic viruses from animals to humans, such as COVID-19, which has caused a global pandemic involving over 184 countries and territories. The study was published in the latest issue of Proceedings of the Royal Society B.

8 Apr 2020

Novel intervention improves outcomes for opioid-dependent mothers and their children

The rate of pregnant women with opioid use disorder, or OUD, when giving birth more than quadrupled from 1999 to 2014, according to the Centers for Disease Control and Prevention.

8 Apr 2020

Adults with irritable bowel syndrome may benefit from mindfulness program

Adults with irritable bowel syndrome experienced fewer gastrointestinal symptoms after they participated in a mindfulness program meant to reduce stress. Results of the study are published in Neurogastroenterology & Motility.

8 Apr 2020

Trial assesses tissue plasminogen activator as a treatment for COVID-19-related respiratory failure

A new study published online in the Journal of Trauma and Acute Care Surgery in March 2020 reports that the anticoagulation drug tPA could be a potential aid in managing respiratory failure in patients with COVID-19.

8 Apr 2020

New anti-COVID-19 system could potentially fight other viruses

The ongoing COVID-19 pandemic has sparked many research projects to meet the challenge of the virus and come up with measures to fight its activity. A new study published in the journal Cell Host & Microbe in April 2020 describes a novel system to help scientists understand the virus, including mutations, diagnose infections, and also to develop and evaluate vaccines more quickly.

8 Apr 2020

Researchers discover inflammatory mechanism that contributes to autoimmune diseases

The protein STING (Stimulator of Interferon Genes) is a critical component of the body's innate immune defence system, but can also contribute to chronic autoimmune and autoinflammatory diseases.

8 Apr 2020

Scientists in the UK look to measure COVID-19 in the wider community

The coronavirus disease (COVID-19) is actively spreading throughout the globe, affecting 184 countries and territories. In the United Kingdom, the country has seen the highest daily numbers of recorded coronavirus deaths – 854 on Monday and 786 on Tuesday, prompting scientists to race toward determining how vast the virus is spreading in the UK.

8 Apr 2020

Common coronaviruses are sharply seasonal and appear to transmit like influenza

Of the seven coronaviruses known to infect people, four cause common respiratory infections that are sharply seasonal and appear to transmit similarly to influenza, according to a new study by University of Michigan School of Public Health researchers.

7 Apr 2020

Bill and Melinda Gates fund potential vaccine against COVID-19

In a race against time, teams of scientists across the world are working towards developing an effective and safe vaccine to prevent infection from the SARS-CoV-2 virus that causes COVID-19 disease.

7 Apr 2020

What we know about COVID-19 in children

A new viewpoint article published in the journal JAMA Pediatrics in April 2020 discusses the manifestation and management of the novel coronavirus disease devastating several countries.

7 Apr 2020

Researchers identify new biomarker to track the development of NAFLD

Fatty liver disease not associated with alcohol consumption, which is called Nonalcoholic Fatty Liver Disease or NAFLD, affects more than one billion people worldwide.

7 Apr 2020

How do viruses mutate and jump to humans?

Zoonotic spillover events like the current novel coronavirus pandemic present threats to human health. But what is zoonotic spillover and how do they occur?

7 Apr 2020

Research reveals a potential 'chink in the armor' of SARS-CoV-2

The scientists from Scripps Research, reveal a likely vulnerability or weakness of the coronavirus. An antibody, called CR3022, recovered from a survivor of the SARS outbreak in 2002, has shown a potential vulnerability of the novel coronavirus.

6 Apr 2020

Tiger with SARS-CoV-2 infection demostrates reverse zoonosis

Some viruses come from animals and jump to humans to cause disease. In the case of the novel coronavirus, now known as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it is thought to have come from bats, jumped to an intermediate animal host, and then onto humans. But can the virus leap from humans to other animals?

6 Apr 2020