CLARITY News and Research

RSS

The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

FDA provides draft guidance focusing on PMAs

For the first time, the U.S. Food and Drug Administration has provided draft guidance clarifying how benefit-risk determinations are made during premarket review of certain medical devices.

16 Aug 2011

Customized computer models may identify patients at risk of Lynch syndrome

People who are at risk for a certain form of colon and other types of cancer may soon have a better chance at surviving or even avoiding the diseases, thanks to a new study done by the Intermountain Clinical Genetics Institute at LDS Hospital.

16 Aug 2011

Study helps clarify definition of gastroesophageal reflux disease

Modifying stomach acid levels may not be enough to treat symptoms in neonates suspected of having gastroesophageal reflux disease. According to a study from Nationwide Children's Hospital, this is the first study to classify reflux and its associated symptoms in neonates based on how and what is refluxed.

9 Aug 2011

GE Healthcare receives FDA clearance for Optima CT660 system

GE Healthcare today announced FDA clearance of Optima CT660 - a powerful and compact Computed Tomography (CT) system offering improvements from its predecessors in diagnostic capabilities at low dose levels, and designed for sustainability and ease-of-use.

9 Aug 2011

NHS doctors’ use of genetic tests leading to infringement of patent rights

NHS doctors are in trouble for over use of diagnostic genetic tests as these infringe upon patents. The British law now recognizes patents on the application of DNA discoveries. But doctors developing genetic tests in NHS hospitals tend to pay no heed to intellectual property.

8 Aug 2011

High fiber diet may help prevent breast cancer: Study

A new study shows women who eat more fiber are less likely to get breast cancer. Chinese researchers found those who ate the most of the healthy plant components were 11 percent less likely to develop breast cancer than women who ate the least.

29 Jul 2011

GE Healthcare introduces Veo CT image reconstruction technology in Canada

GE Healthcare announced the introduction of a breakthrough Computed Tomography (CT) image reconstruction technology, called Veo, in Canada. The industry's first Model-based Iterative Reconstruction (MBIR) technique, Veo is designed to help physicians deliver accurate diagnoses by enabling high CT image quality at significantly lower dose.

25 Jul 2011

Komen for the Cure applauds new mammography guidelines

The American College of Obstetricians and Gynecologists' new recommendation that women begin getting mammograms annually beginning at the age of 40 is a victory for women's health that opens a door to early detection of breast cancer for millions, officials with Susan G. Komen for the Cure said today.

21 Jul 2011

Capitol Hill prepares for politically charged votes on debt limit

With the deadline just about two weeks away, lawmakers continue to struggle to reach an agreement surrounding the effort to raise the nation's borrowing limit.

18 Jul 2011

Congress should avoid cutting international affairs budget, Clinton says

Secretary of State Hillary Rodham Clinton argued against cutting U.S. foreign aid in a speech on Tuesday at a meeting of U.S. Global Leadership Coalition, the Washington Post's "Checkpoint Washington" blog reports.

15 Jul 2011

Obama administration rolls out rule for health exchanges

In a big step to carry out the new health care law, the Obama administration unveiled standards on Monday for insurance marketplaces that will allow individuals, families and small businesses in every state to shop for insurance, compare prices and benefits and buy coverage.

13 Jul 2011

BioLineRx initiates enrollment in BL-1020 Phase II/III trial against schizophrenia

BioLineRx, a biopharmaceutical development company, announced today the enrollment of the first patient in the Phase II/III CLARITY clinical trial of BL-1020, a first in class, orally available, GABA-enhanced antipsychotic for the treatment of schizophrenia.

28 Jun 2011

Saint-Gobain introduces new C-Flex ULTRA TPE pump tubing for biopharmaceutical applications

Saint-Gobain Performance Plastics has expanded its line of thermoplastic elastomer (TPE) tubing with the addition of new C-Flex® ULTRA pump tubing, a product designed specifically to perform in demanding biopharmaceutical applications such as pumping, single-use assemblies, process filling and sampling.

15 Jun 2011

FDA issues final rulemaking on testing and labeling of sunscreen products

"FDA's recognition today of the important role sunscreens play in protecting the public not only from sunburn but also from skin cancer and premature aging due to the sun is a very significant victory for public health. The role of UV rays in causing skin damage and the role of sunscreens in protecting against this sun damage are widely acknowledged within the medical and scientific communities, and we're very pleased the agency has taken this critical step.

15 Jun 2011

ACS honors Los Angeles general surgeon with 2011 Jacobson Innovation Award

George Berci, MD, FACS, FRCS, Ed. (Hon), a general surgeon from Los Angeles, CA, is the recipient of the 2011 Jacobson Innovation Award of the American College of Surgeons.

13 Jun 2011

FDA draft guidance outlines roadmap for discussion on nanotechnology in regulated products

The U.S. Food and Drug Administration today released draft guidance to provide regulated industries with greater certainty about the use of nanotechnology, which generally involves materials made up of particles that are at least one billionth of a meter in size. The guidance outlines the agency's view on whether regulated products contain nanomaterials or involve the application of nanotechnology.

10 Jun 2011

Adaptive optics technology reveals eye's cellular structure with unprecedented detail

Scientists today reported that the tiny light-sensing cells known as rods have been clearly and directly imaged in the living eye for the first time. Using adaptive optics (AO), the same technology astronomers use to study distant stars and galaxies, scientists can see through the murky distortion of the outer eye, revealing the eye's cellular structure with unprecedented detail.

9 Jun 2011

GTx to initiate two Ostarine Phase III trial for treatment of muscle wasting in patients with NSCLC

Following the conclusion of a series of meetings with the United States Food and Drug Administration (FDA), GTx, Inc. announced today the clinical trial design for the two Phase III Ostarine registration studies for the prevention and treatment of muscle wasting in patients with non-small cell lung cancer (NSCLC).

6 Jun 2011

Orexigen meets FDA to gain clarity on approval for Contrave NDA to treat obesity

Orexigen Therapeutics, Inc. announced today that it recently met with the Food and Drug Administration (FDA) regarding the New Drug Application for Contrave (naltrexone HCl/bupropion HCl) extended-release tablets for the treatment of obesity, including weight loss and maintenance of weight loss.

3 Jun 2011

New imaging method using fluorescent nanotubes can peer clearly into living mouse's innards

Developing drugs to combat or cure human disease often involves a phase of testing with mice, so being able to peer clearly into a living mouse's innards has real value.

30 May 2011