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Comprehensive whole genome sequencing provides new insight into the 'genomic architecture' of autism

Researchers from The Hospital for Sick Children (SickKids) have uncovered new genes and genetic changes associated with autism spectrum disorder (ASD) in the largest autism whole genome sequencing analysis to date, providing better understanding into the 'genomic architecture' that underlies this disorder.

10 Nov 2022

Researchers illuminate the role of extracellular vesicles in cancer progression

The advent of cell phones, the internet, and various messaging platforms has allowed for faster and broader communication worldwide.

10 Nov 2022

New CRISPR approach is a leap forward in developing personalized treatment for cancer

For the first time, scientists have used CRISPR technology to insert genes that allow immune cells to focus their attack on cancer cells, potentially leaving normal cells unharmed and increasing the effectiveness of immunotherapy.

10 Nov 2022

Study illuminates how a typical gut bacterium spreads through the body

A typical gut bacterium that can spread through the body and cause a serious infection resists natural immune defenses and antibiotics by enhancing its protective outer layer, known as the cell envelope, according to a new study by Weill Cornell Medicine investigators.

10 Nov 2022

Experimental therapeutic cancer vaccine leads to significant tumor regression in mice

An experimental therapeutic cancer vaccine induced two distinct and desirable immune system responses that led to significant tumor regression in mice, report investigators from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

10 Nov 2022

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Researchers reviewed research advancements showing the significant role both innate and adaptive immune systems play in the pathological course of Alzheimer’s disease.

10 Nov 2022

Enzyme that drives growth of medulloblastoma may hold the key to future treatment

An enzyme that drives the growth of an often-lethal childhood brain cancer may hold the key to a future treatment, says a McMaster University-led study.

10 Nov 2022

Research reveals why stem cell transplants are so successful in MS patients

Blood stem cell transplantation is a radical but highly effective therapy for multiple sclerosis. A study led by the University of Zurich has now examined in detail the way in which the treatment curbs the autoimmune disease and how the immune system regenerates afterwards.

10 Nov 2022

TYK2 inhibitor identifies as a promising drug candidate for preventing type 1 diabetes

According to a study, type 1 diabetes could be prevented by inhibiting a gene associated with the onset of the disease.

10 Nov 2022

Researchers demonstrate that neutralizing antibody titers wane over time in ChAdOx1, BNT162b2 and mRNA-1273 vaccinees

Researchers investigated the neutralization antibody titers and the efficacy of the humoral and cellular immunities in individuals vaccinated with three COVID-19 vaccines.

10 Nov 2022

MicroRNAs can upregulate proteins in addition to downregulating protein production

microRNAs can play a role in cancer development and are thought to exclusively suppress protein expression in dividing cells, such as tumor cells.

10 Nov 2022

Duke scientists join team involved in the first use of fetal therapy for Pompe disease

Experts at Duke Health were among a multi-national team involved in treating a fetus for infantile-onset Pompe disease using an enzyme replacement therapy - a first in the world.

9 Nov 2022

Researchers characterize subtle differences in the brains of primates and humans

While the physical differences between humans and non-human primates are quite distinct, a new study reveals their brains may be remarkably similar. And yet, the smallest changes may make big differences in developmental and psychiatric disorders.

9 Nov 2022

Biodegradable transport nanoparticle can make anti-inflammatory drug more effective and less toxic

A team from UNIGE and LMU developed a transport nanoparticle to make an anti-inflammatory drug much more effective and less toxic.

9 Nov 2022

Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cells

In a recent study posted to the Research Square* preprint server and under review at the Nature Portfolio journal, researchers reported activation and maturation of antigen-presenting cells (APCs) by lipid nanoparticles (LNPs).

9 Nov 2022

First transfusions of lab-grown blood

Two patients in the United Kingdom received two small doses of lab-grown blood samples as part of the RESTORE trial.

9 Nov 2022

Researchers discover residual tumor cells responsible for colon cancer relapse

Colon cancer is the third most common cancer in the world, with about 2 million new cases each year. Most patients are diagnosed when the tumor is still located in the colon or rectum.

9 Nov 2022

New tool maps how breast cancer grows in previously unseen detail

New technology can trace which populations of breast cancer cells are responsible for the spread of the disease, and for the first time highlights how the location of cancer cells could be as important as mutations in tumor growth.

9 Nov 2022

Tissue nanotransfection shows promise as a treatment for traumatic muscle loss

Technology developed by researchers at the Indiana University School of Medicine that can change skin tissue into blood vessels and nerve cells has also shown promise as a treatment for traumatic muscle loss.

9 Nov 2022

Researchers unravel neurobiological mechanisms impacted by early life adversity

Using cutting edge molecular techniques in rodent models, researchers are dissecting the neurobiological mechanisms impacted by early life adversity.

9 Nov 2022

Cell News and Research

Comprehensive whole genome sequencing provides new insight into the 'genomic architecture' of autism

Researchers illuminate the role of extracellular vesicles in cancer progression

New CRISPR approach is a leap forward in developing personalized treatment for cancer

Study illuminates how a typical gut bacterium spreads through the body

Experimental therapeutic cancer vaccine leads to significant tumor regression in mice

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Enzyme that drives growth of medulloblastoma may hold the key to future treatment

Research reveals why stem cell transplants are so successful in MS patients

TYK2 inhibitor identifies as a promising drug candidate for preventing type 1 diabetes

Researchers demonstrate that neutralizing antibody titers wane over time in ChAdOx1, BNT162b2 and mRNA-1273 vaccinees

MicroRNAs can upregulate proteins in addition to downregulating protein production

Duke scientists join team involved in the first use of fetal therapy for Pompe disease

Researchers characterize subtle differences in the brains of primates and humans

Biodegradable transport nanoparticle can make anti-inflammatory drug more effective and less toxic

Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cells

First transfusions of lab-grown blood

Researchers discover residual tumor cells responsible for colon cancer relapse

New tool maps how breast cancer grows in previously unseen detail

Tissue nanotransfection shows promise as a treatment for traumatic muscle loss

Researchers unravel neurobiological mechanisms impacted by early life adversity

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