Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Combination of probiotics and herbal supplement may prolong lifespan, research shows

You are what you eat. Or so the saying goes. Science now tells us that we are what the bacteria living in our intestinal tract eat and this could have an influence on how well we age.

1 Jun 2018

Study: Cellular housekeeping can help mammals live longer and healthier

Building on two decades of research, investigators at UT Southwestern have determined that "cellular housekeeping" can extend the lifespan and healthspan of mammals.

31 May 2018

Tau mutations may serve as novel risk factor for cancer

Mutations to the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer, according to results published in Cancer Research, a journal of the American Association for Cancer Research.

24 May 2018

Small part of cellular protein that helps form long-term memories also drives neurodegeneration

Scientists have just discovered that a small region of a cellular protein that helps long-term memories form also drives the neurodegeneration seen in Amyotrophic Lateral Sclerosis (ALS). This small part of the Ataxin-2 protein thus works for good and for bad.

23 May 2018

Researchers discover link between tuberculosis and Parkinson's disease

The mechanism our immune cells use to clear bacterial infections like tuberculosis (TB) might also be implicated in Parkinson's disease, according to a new collaborative study led by the Francis Crick Institute, Newcastle University and GSK.

22 May 2018

Study: Lifetime risks of developing Alzheimer's dementia vary by age, gender

Lifetime risks of developing Alzheimer's disease dementia vary considerably by age, gender and whether any signs or symptoms of dementia are present, according to a new study published online by Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

22 May 2018

New tool predicts the lifetime risk of Alzheimer’s

A new study has shown that the risk of Alzheimer’s disease significantly varies depending on age, gender and the presence of any signs or symptoms of dementia.

22 May 2018

Study: Most people with preclinical signs of Alzheimer's disease may not develop dementia

During the past decade, researchers have identified new ways to detect the earliest biological signs of Alzheimer's disease.

22 May 2018

New study could have important implications for cellular aging

Researchers have found a way to stimulate autophagy, a process used by cells to convert misfolded proteins and redundant organelles into components that the cell can re-use.

16 May 2018

Researchers demonstrate new strategy for stimulating autophagy

Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts.

16 May 2018

Researchers reverse Alzheimer's symptoms in flies by restoring epigenetic balance

Researchers from Drexel University reversed symptoms of Alzheimer's disease in fruit flies by restoring the balance between two epigenetic enzymes that regulate gene expression, a study shows.

15 May 2018

New tool provides high accuracy and precision in analyzing disease and drug effects

A new protein analysis tool developed at the University at Buffalo could vastly increase the speed and precision with which disease and drug effects are analyzed.

11 May 2018

UAB researchers unravel brain neuron dysfunction in Parkinson’s disease and dementia with Lewy bodies

A decay of brain function is a hallmark of Parkinson's disease and dementia with Lewy bodies, or DLB. Specifically, cognitive dysfunction defines DLB, and nearly eight of every 10 Parkinson's patients develop dementia.

11 May 2018

Researchers devise neuronal cookbook for turning skin cells into different types of neurons

Scientists at The Scripps Research Institute have devised what they call a "neuronal cookbook" for turning skin cells into different types of neurons.

10 May 2018

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

A new study in Biological Psychiatry reports that dementia-related and psychiatric-related proteins cluster together to form aggregates in the brain, leading to abnormal cell function and behavior.

8 May 2018

Study adds robust evidence to higher prevalence of Alzheimer's among women than men

The APOE gene, the strongest genetic risk factor for Alzheimer's disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer's Center.

8 May 2018

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus- they play an essential role in the survival of T cells.

8 May 2018

Researchers characterize new protein that plays key role in genetic stability of cells

Researchers from the Novo Nordisk Foundation Center for Protein Research at the Faculty of Health and Medical Sciences have characterized a new protein that is important to the genetic stability of our cells.

3 May 2018

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

One major hallmark of cancer cells is their ability to adapt to stressful conditions such as nutrient deprivation. Rapidly growing tumor cells must compete for the ever-diminishing supply of nutrients in the surrounding environment to survive and proliferate. Targeting these adaptive mechanisms represents a promising approach for cancer therapeutics.

3 May 2018

3D structures of nicotine receptor could lead to new ways for treating addiction

UT Southwestern researchers today published in Nature atomic-scale blueprints of the most abundant class of brain nicotinic acetylcholine receptors. A structural understanding of the protein, found in neurons, could lead to new ways to treat nicotine addiction from smoking and vaping.

3 May 2018

Neurodegeneration News and Research

Further Reading

Combination of probiotics and herbal supplement may prolong lifespan, research shows

Study: Cellular housekeeping can help mammals live longer and healthier

Tau mutations may serve as novel risk factor for cancer

Small part of cellular protein that helps form long-term memories also drives neurodegeneration

Researchers discover link between tuberculosis and Parkinson's disease

Study: Lifetime risks of developing Alzheimer's dementia vary by age, gender

New tool predicts the lifetime risk of Alzheimer’s

Study: Most people with preclinical signs of Alzheimer's disease may not develop dementia

New study could have important implications for cellular aging

Researchers demonstrate new strategy for stimulating autophagy

Researchers reverse Alzheimer's symptoms in flies by restoring epigenetic balance

New tool provides high accuracy and precision in analyzing disease and drug effects

UAB researchers unravel brain neuron dysfunction in Parkinson’s disease and dementia with Lewy bodies

Researchers devise neuronal cookbook for turning skin cells into different types of neurons

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

Study adds robust evidence to higher prevalence of Alzheimer's among women than men

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Researchers characterize new protein that plays key role in genetic stability of cells

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

3D structures of nicotine receptor could lead to new ways for treating addiction

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