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Combination of pazopanib and paclitaxel shows promise in slowing anaplastic thyroid cancer

A combination of the drugs pazopanib and paclitaxel shows promise in slowing anaplastic thyroid cancer (ATC), according to a Mayo Clinic-led study published in the journal Science Translational Medicine.

9 Jan 2013

Cost-ineffective drug prescribing practices revealed

Around four in 10 physicians prescribe a brand-name drug due to a patient request, when a generic equivalent is available, find researchers.

8 Jan 2013

Lack of knowledge key to poor disabled access in primary care

Research suggests that a lack of knowledge about available accessible medical equipment among practice administrators makes primary healthcare difficult to access for patients with disabilities.

8 Jan 2013

Trovagene, MD Anderson partner to detect transrenal BRAF mutations in metastatic cancers

Trovagene, Inc., a developer of transrenal molecular diagnostics, announced that it has entered into a clinical collaboration with The University of Texas MD Anderson Cancer Center to detect transrenal BRAF mutations in the urine of patients with advanced or metastatic cancers.

3 Jan 2013

$Bayer, Onyx announce data from Nexavar Phase 3 trial on RAI-refractory differentiated thyroid cancer$

Bayer, Onyx announce data from Nexavar Phase 3 trial on RAI-refractory differentiated thyroid cancer

Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals, Inc. today announced that a Phase 3 trial of Nexavar (sorafenib) tablets in patients with locally advanced or metastatic radioactive iodine-refractory (RAI) differentiated thyroid cancer has met its primary endpoint of a statistically significant improvement of progression-free survival.

3 Jan 2013

Inpatient mortality increased by emergency department overcrowding

Periods of high crowding at emergency departments have a detrimental impact on outcomes, with increased patient mortality, length of hospital stay, and healthcare costs for admitted patients, US study findings indicate.

2 Jan 2013

World Trade Center rescue workers may face increased cancer risk

People who were involved in the rescue and recovery operation at the World Trade Center are at an increased risk for certain types of cancer, including prostate, thyroid, and myeloma, study findings suggest.

31 Dec 2012

Hospitalist handoff needs action

Active listening occurs infrequently between hospitalists as they handoff patients during shift and service changes, show US study results.

31 Dec 2012

Improvement needed in at-home cardiac care for elderly

Elderly patients with coronary heart disease who refuse an offer of center-based cardiac rehabilitation and receive an at-home plan instead fare no better after 12 months than their counterparts who receive usual care, report researchers.

31 Dec 2012

Ease of use, usefulness keep patients e-happy

Ensuring that patients are loyal toward targeted online services comes down to whether they perceive the service to be useful and that the service is easy to use, report Spanish researchers.

28 Dec 2012

Subclinical hypothyroidism not a risk factor for heart disease

Persistent subclinical hypothyroidism in older adults is not associated with an increased risk for cardiovascular events, US research shows.

28 Dec 2012

Surgeons: Support your low-income neighbor

Patients with cancer in low-income nations present for surgical treatment at a young age, advanced stage of disease, and often receive palliative rather than curative procedures, suggests a study in Malawi.

28 Dec 2012

Diabetes interventions show promise in primary care

Two lifestyle-based diabetes interventions developed in a clinical trial could successfully promote weight loss in primary care, research shows.

28 Dec 2012

Key to at-home geriatric care lies in reliability

Older individuals who live at home but are dependent on healthcare services perceive their care delivery system to be effective when it involves supportive and reliable services, indicate UK study results.

24 Dec 2012

Nurse behavior makes patients feel safe

Hospitalized patients over the age of 65 years feel safe in hospital when their nurses can anticipate and provide attentive care, are predictable and responsive, interact on a personal level, and advocate or intervene on their behalf, indicate study results.

22 Dec 2012

Study finds increased risk of cancers among rescue/recovery workers after WTC terrorist attack

Among rescue and recovery workers exposed to the dust, debris, and fumes following the World Trade Center terrorist attack, there was an increased incidence of prostate and thyroid cancers and multiple myeloma, although it is not clear how big a factor medical screening and non-WTC risk factors contributed to these increases, according to a study in the December 19 issue of JAMA.

21 Dec 2012

Study finds no clear indication 9/11 debris causes cancer

The study, published in the Journal of the American Medical Association, examined the health of nearly 56,000 people.

20 Dec 2012

GI bacteria exert some control over their hosts' appetites: Review

Over the last half decade, it has become increasingly clear that the normal gastrointestinal (GI) bacteria play a variety of very important roles in the biology of human and animals. Now Vic Norris of the University of Rouen, France, and coauthors propose yet another role for GI bacteria: that they exert some control over their hosts' appetites.

20 Dec 2012

Investigators report non-coding miRNAs as appealing biomarkers for cancer malignancy

As many as 50 percent of all human protein-coding genes are regulated by microRNA (miRNA) molecules. While some miRNAs impact onset and progression of cancer, others can actually suppress the development of malignant tumors and are useful in cancer therapy. They can also serve as potential biomarkers for early cancer detection. In a new issue of Cancer Biomarkers, investigators report on non-coding miRNAs as appealing biomarkers for malignancy.

20 Dec 2012

Ethnic disparities remain in glaucoma testing

A decade’s worth of data show that Hispanic men and women are less likely than individuals of other race or ethnicity to undergo ocular imaging for glaucoma.

19 Dec 2012