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Light-Seq technology for barcoding and deep-sequencing selected cell populations in tissues

Under the microscope, researchers often observe different cell types organizing themselves in peculiar patterns within tissues, or sometimes a rare cell type that stands out by occupying a unique position, exhibiting an unusual shape, or expressing a specific biomarker molecule.

10 Oct 2022

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

A new paper reviews current knowledge of RdRp inhibitors that could be developed further to provide broadly effective antivirals against SARS-CoV-2 in particular and CoVs in general.

10 Oct 2022

Brain changes can be studied in very early stages of neurodegenerative diseases

Many changes take place in the brain long before symptoms appear. This has been shown in mice in two studies of prion diseases in which the brain gradually deteriorates.

10 Oct 2022

The role of oxidative stress in congenital syndromes

Researchers discuss the role of oxidative stress in genetic conditions.

10 Oct 2022

Zinc could improve the brain defects caused by rare genetic disorder

Pediatric encephalopathies of genetic origin cause severe motor and intellectual disabilities from birth. One of these diseases, first identified in 2013, is caused by mutations in the GNAO1 gene.

10 Oct 2022

KAUST research could open new avenues for cancer drug development

Precise details of how a master regulator of gene expression binds its activating partner could open new avenues for cancer drug development.

10 Oct 2022

Chronic liver disease in COVID-19 patients

A recent study summarizes the clinical outcomes of COVID-19 patients with chronic liver disease.

10 Oct 2022

Sartorius releases the 6th edition of its popular live-cell analysis handbook

Sartorius, a leader in new technologies for real-time, live-cell imaging and analysis, has released the 6th edition of its popular Live-Cell Analysis Handbook.

From Sartorius 10 Oct 2022

Reduced expression of interleukin 8 and interferon-gamma cytokines identified in long COVID

In a new study, researchers compared serum cytokine expression among healthy individuals and those with PASC [post-acute sequelae of coronavirus disease 2019 (COVID-19)].

10 Oct 2022

New class of drugs can safely counter allergic asthma without creating vulnerability to infections

Blocking the action of calcium signals in immune cells suppresses the most common form of asthma, but without compromising the body's defenses against flu viruses, a new study finds.

7 Oct 2022

NEI researchers create a high-resolution map of retinal cell chromatin contract points

National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell's nucleus.

7 Oct 2022

Research identifies new clue for preventing and treating gliomas

An important new clue for preventing and treating brain tumors known as gliomas has been identified in research led by the Lunenfeld-Tannenbaum Research Institute (LTRI) at Mount Sinai Hospital in Toronto and Mayo Clinic Comprehensive Cancer Center and Mayo Clinic Center for Individualized Medicine.

7 Oct 2022

Opioid receptor levels in brown fat found to be dependent on the length of daylight hours

Researchers from the Turku PET Centre, Finland, have observed that the length of daylight hours impacts opioid receptor levels in brown fat.

7 Oct 2022

Study uncovers how the TAZ protein protects hematopoietic stem cells from aging

A well-functioning immune system is essential for protection against infections. However, with increasing age, the functioning of the immune system diminishes, which is also due to age-related damage in hematopoietic (blood) stem cells.

7 Oct 2022

Researchers take new approach to studying the development of the human brain

Researchers at ETH Zurich are growing human brain-like tissue from stem cells and are then mapping the cell types that occur in different brain regions and the genes that regulate their development.

7 Oct 2022

Research shows highly disturbed metabolic pathways in people with type 2 diabetes

Using state of the art techniques, researchers from Uppsala University have shown that the metabolism in patients with type 2 diabetes and prediabetes was much more disturbed than previously known, and that it varied between organs and severity of the disease.

7 Oct 2022

WVU biomedical engineer receives $1.2 million to improve early detection of tick-borne infections

A team led by a West Virginia University biomedical engineer is working to ramp up and reimagine how medical professionals diagnose tick-borne infections such as Lyme disease.

7 Oct 2022

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

Researchers demonstrated that the SARS-CoV-2 protein functions as a histone mimic to disrupt the epigenetic regulation of host cells.

7 Oct 2022

The effect of ORF3c, a SARS-CoV-2 accessory protein, on cellular innate immune responses, autophagy, and lung cell mitochondrial metabolism

Researchers explored the role of the ORF3c, a SARS-CoV-2 accessory protein not so extensively studied as yet.

7 Oct 2022

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

Researchers examined the replicative capacity of seven SARS-CoV-2 isolates in 17 cell lines to understand their phenotypic variations and host range.

7 Oct 2022

Cell News and Research

Light-Seq technology for barcoding and deep-sequencing selected cell populations in tissues

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

Brain changes can be studied in very early stages of neurodegenerative diseases

The role of oxidative stress in congenital syndromes

Zinc could improve the brain defects caused by rare genetic disorder

KAUST research could open new avenues for cancer drug development

Chronic liver disease in COVID-19 patients

Sartorius releases the 6th edition of its popular live-cell analysis handbook

Reduced expression of interleukin 8 and interferon-gamma cytokines identified in long COVID

New class of drugs can safely counter allergic asthma without creating vulnerability to infections

NEI researchers create a high-resolution map of retinal cell chromatin contract points

Research identifies new clue for preventing and treating gliomas

Opioid receptor levels in brown fat found to be dependent on the length of daylight hours

Study uncovers how the TAZ protein protects hematopoietic stem cells from aging

Researchers take new approach to studying the development of the human brain

Research shows highly disturbed metabolic pathways in people with type 2 diabetes

WVU biomedical engineer receives $1.2 million to improve early detection of tick-borne infections

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

The effect of ORF3c, a SARS-CoV-2 accessory protein, on cellular innate immune responses, autophagy, and lung cell mitochondrial metabolism

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

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