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Research sheds light on how the cell selects suitable protein fragments for robust T-cell response

As task forces of the adaptive immune system, T lymphocytes are responsible for attacking and killing infected or cancerous cells.

30 Sep 2022

Obscure family of viruses already endemic in African monkeys "poised for spillover" to humans

An obscure family of viruses, already endemic in wild African primates and known to cause fatal Ebola-like symptoms in some monkeys, is "poised for spillover" to humans, according to new University of Colorado Boulder research published online Sept. 30 in the journal Cell.

30 Sep 2022

The compositional and functional diversity of the gut fungal microbiome

Researchers assessed the role of gut bacterial microbiome assembly and the gut mycobiome in relation to health, pathology, and clinical applications.

30 Sep 2022

SARS-CoV-2 spike protein and messenger ribonucleic acid found to translocate into the nucleus

In a new study, researchers reported severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) spike (S) protein and S messenger ribonucleic acid (mRNA) nuclear co-translocation as a novel feature of SARS-CoV-2 pathogenesis.

30 Sep 2022

Plasma proteome signature predictive of occurrence of persistent symptoms following SARS-CoV-2 infection

In a new study, researchers performed a proteomic multiple-reaction monitoring analysis of 91 pre-selected proteins using the plasma samples of 156 healthcare workers (HCW) in the United Kingdom (UK).

30 Sep 2022

High-resolution pangenome dataset provides genetic insights into domestic and wild silkworm

BGI Genomics, in collaboration with Southwest University, the State Key Laboratory of Silkworm Genome Biology, and other partners, has constructed a high-resolution pangenome dataset representing almost the entire genomic content in a silkworm.

30 Sep 2022

What is the efficacy of curcumin as a photosensitizer, prophylactic and therapeutic agent against SARS-CoV-2?

In a new study, researchers investigated the efficacy of curcumin as a blue light photosensitizing agent for photodynamic therapy (PDT), as a prophylactic agent, and as a therapeutic agent against SARS-CoV-2.

30 Sep 2022

Effectiveness of anti-SARS-CoV-2 immunoadhesin against omicron and other emerging variants

A new study demonstrated the efficacy of a newly engineered angiotensin-converting enzyme 2 (ACE2) based immunoadhesin against Omicron and other SARS-CoV-2 VOCs.

30 Sep 2022

Oxytocin induces epicardial cell proliferation, study finds

The neurohormone oxytocin is well-known for promoting social bonds and generating pleasurable feelings, for example from art, exercise, or sex. But the hormone has many other functions, such as the regulation of lactation and uterine contractions in females, and the regulation of ejaculation, sperm transport, and testosterone production in males.

30 Sep 2022

Patients with scleroderma have reduced levels of Cathepsin L

Much of the research on scleroderma, a connective tissue disease that causes scarring, or fibrosis, has focused on the increased number of proteins promoting fibrosis in these patients. A Medical University of South Carolina (MUSC) research team took a different tact and measured the levels of an antifibrotic protein, Cathepsin L, in these patients.

30 Sep 2022

Study reveals the role of autophagy in competitive elimination of cancer cells

Elimination of transformed cells that can initiate cancer is necessary to maintain tissue integrity. In a new study, scientists from Tokyo University of Science show how this mechanism is regulated by the cellular process “autophagy.”

30 Sep 2022

Love hormone can activate heart repair mechanisms after cardiac injury, study finds

Researchers show for the first time that the neurohormone oxytocin has a previously unsuspected function in both zebrafish and human cell cultures: it stimulates mature cells in the epicardium of the heart to become stem-like cells, which can replace heart cells lost after damage.

30 Sep 2022

Bioactive compounds derived from Ganoderma lucidum exhibit anti-SARS-CoV-2 activity

Scientists have identified lucidenic acid A, one of the bioactive compounds of Ganoderma lucidum, as a potential inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) host cell entry. The study has recently been published in the journal Food and Chemical Toxicology.

29 Sep 2022

Many diverse nanopore research directions and applications beyond DNA sequencing

In a recent Nature Nanotechnology study, researchers describe diverse applications of nanopore-based technology beyond deoxyribonucleic acid (DNA) sequencing. More specifically, the current research focuses on the advancements of this technology within chemistry, biophysics, and nanoscience.

29 Sep 2022

Pluripotent bat stem cells as a model to study novel viruses

Researchers generate induced pluripotent stem cells from bats using to establish bats as a novel in vivo model study species.

29 Sep 2022

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Researchers discuss a robust method to identify mutations that improve the expression and stabilize the conformation of the SARS-CoV-2 spike protein.

29 Sep 2022

Tufted cells are better at recognizing smells than mitral cells, researchers say

Since their discovery over 100 years ago, neurons in the brain's olfactory bulb called tufted cells have been difficult to study.

29 Sep 2022

Researchers propose guidelines and methods for consistently generating high-quality brain organoids

By using stem cells to grow miniature brain-like organs in the lab, scientists have opened a new avenue for studies of neurological development, disease and therapies that can't be conducted in living people.

29 Sep 2022

“Mystery gene” matures a main component of the cell skeleton

"I'm a professional pin-in-a-haystack seeker," geneticist Thijn Brummelkamp responds when asked why he excels at tracking down proteins and genes that other people did not find, despite the fact that some have managed to remain elusive for as long as forty years.

29 Sep 2022

Researchers discover how cancer cells can turn off the immune system to help tumors grow

When cancer arises in the body, it starts with tumor cells that rapidly grow and divide and eventually spread.

29 Sep 2022

Cell News and Research

Research sheds light on how the cell selects suitable protein fragments for robust T-cell response

Obscure family of viruses already endemic in African monkeys "poised for spillover" to humans

The compositional and functional diversity of the gut fungal microbiome

SARS-CoV-2 spike protein and messenger ribonucleic acid found to translocate into the nucleus

Plasma proteome signature predictive of occurrence of persistent symptoms following SARS-CoV-2 infection

High-resolution pangenome dataset provides genetic insights into domestic and wild silkworm

What is the efficacy of curcumin as a photosensitizer, prophylactic and therapeutic agent against SARS-CoV-2?

Effectiveness of anti-SARS-CoV-2 immunoadhesin against omicron and other emerging variants

Oxytocin induces epicardial cell proliferation, study finds

Patients with scleroderma have reduced levels of Cathepsin L

Study reveals the role of autophagy in competitive elimination of cancer cells

Love hormone can activate heart repair mechanisms after cardiac injury, study finds

Bioactive compounds derived from Ganoderma lucidum exhibit anti-SARS-CoV-2 activity

Many diverse nanopore research directions and applications beyond DNA sequencing

Pluripotent bat stem cells as a model to study novel viruses

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Tufted cells are better at recognizing smells than mitral cells, researchers say

Researchers propose guidelines and methods for consistently generating high-quality brain organoids

“Mystery gene” matures a main component of the cell skeleton

Researchers discover how cancer cells can turn off the immune system to help tumors grow

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