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Stem cell transplantation produces prolonged survival with improved safety in patients with AL amyloidosis

AL amyloidosis is a life-threatening disease related to bone marrow cancer, multiple myeloma. It is caused when a person's antibody-producing white blood cells (i.e. plasma cells) do not function properly and generate abnormal protein which misfolds to form amyloid fibrils and deposits made of components of antibodies called light chains, which then deposit in various organs of the body.

14 Jul 2022

Y chromosome loss in men can lead to deadly heart failure, research shows

The loss of the male sex chromosome as many men age causes the heart muscle to scar and can lead to deadly heart failure, new research from the University of Virginia School of Medicine shows.

14 Jul 2022

Minimally invasive skin biopsy can help assess tissue damage related to SARS-CoV-2 infection

Using skin biopsy samples, investigators found that patients with severe COVID-19 had clots in small venous and arterial blood vessels in skin that appears normal.

14 Jul 2022

New liquid biopsy test found to be highly accurate, sensitive for both NASH and liver fibrosis

Researchers have created a liquid biopsy test, which uses two circulating proteins, to test for major liver diseases.

14 Jul 2022

A stepped regimen of anti-VEFG drugs leads to good vision outcomes in diabetic macular edema

Clinical trial results from the DRCR Retina Network suggest that a specific step strategy, in which patients with diabetic macular edema start with a less expensive medicine and switch to a more expensive medicine if vision does not improve sufficiently, gives results similar to starting off with the higher-priced drug.

14 Jul 2022

Risk profiles in adults with cardiovascular disease fail to improve despite advances guidelines and treatments

In an analysis of medical information of more than 6,000 American adults with a history of cardiovascular disease (CVD), researchers at Johns Hopkins Medicine conclude that CVD risk "profiles" in secondary prevention have failed to improve over the last two decades.

14 Jul 2022

Antibody signatures strongly associated with SARS-CoV-2 immunopathology identified using a novel B cell epitope discovery method

A recent study discovered antibody footprints strongly correlated with immunopathology of SARS-CoV-2 infection using a new B cell epitope identification approach

14 Jul 2022

Diabetes screening missed by many men in their 40s, research shows

Not enough men in Alberta, Canada - especially those in their 40s - are getting tested for diabetes, putting them at risk for heart disease, cancer and other complications, according to new population health research published today in The Lancet Regional Health - Americas.

14 Jul 2022

Researchers identify fusion peptide-specific monoclonal antibodies with broad neutralizing activity

Neutralizing mAbs identified in the current study sheds light on ACE2-triggered conformational change that restricts the immunogenicity of the highly conserved FP region.

14 Jul 2022

Integrating mental health support with routine care is essential for people with congenital heart defects

Although many individuals born with congenital heart defects develop resilience and have a high quality of life, they may face a variety of health-related psychological and social challenges throughout their lives.

14 Jul 2022

Community area's death rate from heart disease decreases along with decline in violent crime

In addition to keeping city residents safer where they live, work, and play, , a new analysis of data from Chicago shows that as violent crime decreases, so does the area's death rate from heart disease.

14 Jul 2022

Long-established drug for angina pectoris shows anti-inflammatory effect, reduces atherosclerotic plaques

A drug used in the clinical treatment of angina symptoms also has an anti-inflammatory effect and reduces atherosclerotic plaques in blood vessels - thereby reducing the risk of heart attack or stroke.

14 Jul 2022

Study finds SARS-CoV-2 transmission in children and adolescents is lower than adults

Researchers observed lower susceptibility of children and adolescents to SARS-CoV-2 infection.

14 Jul 2022

Children born to mothers with PCOS have increased risk of developing childhood illnesses

Children born to mothers with polycystic ovary syndrome (PCOS) have an increased risk of developing infections, allergies and other childhood illnesses by the age of 13, according to the largest study to investigate this.

14 Jul 2022

Researchers may be one step closer to preventing Type 1 diabetes

Australian researchers may be a step closer to preventing Type 1 diabetes after identifying a crucial protein that could prevent the autoimmune disease from taking hold.

14 Jul 2022

People with non-alcoholic fatty liver disease may have higher risk of dementia

People who have non-alcoholic fatty liver disease, a buildup of fat cells in the liver, may have a higher risk of dementia, according to a new study published in the July 13, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

13 Jul 2022

New chemical biological tools could help better understand the progression of Parkinson's disease

Researchers are a step closer to understanding how Parkinson's disease develops and progresses thanks to chemical biological tools developed at Simon Fraser University.

13 Jul 2022

Study describes biochemical pathway that leads to inflammation characteristic of autoimmune diseases

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and well-being.

13 Jul 2022

Geisinger researchers receive two grants to study risk factors linked with familial hypercholesterolemia

Geisinger researchers have been awarded two grants from the National Heart, Lung and Blood Institute, part of the National Institutes of Health, to study risk factors associated with familial hypercholesterolemia (FH) and ways to improve screening, diagnosis and communication with patients.

13 Jul 2022

New center aims to accelerate research into biomarkers of neurodegenerative diseases

A new center established at Washington University School of Medicine in St. Louis aims to accelerate research into biomarkers of neurodegenerative conditions such as Huntington's and Parkinson's diseases, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS) and the so-called tauopathies, a group that includes Alzheimer's disease along with rarer diseases such as frontotemporal dementia, corticobasal syndrome and progressive supranuclear palsy.

13 Jul 2022

Blood News and Research

Stem cell transplantation produces prolonged survival with improved safety in patients with AL amyloidosis

Y chromosome loss in men can lead to deadly heart failure, research shows

Minimally invasive skin biopsy can help assess tissue damage related to SARS-CoV-2 infection

New liquid biopsy test found to be highly accurate, sensitive for both NASH and liver fibrosis

A stepped regimen of anti-VEFG drugs leads to good vision outcomes in diabetic macular edema

Risk profiles in adults with cardiovascular disease fail to improve despite advances guidelines and treatments

Antibody signatures strongly associated with SARS-CoV-2 immunopathology identified using a novel B cell epitope discovery method

Diabetes screening missed by many men in their 40s, research shows

Researchers identify fusion peptide-specific monoclonal antibodies with broad neutralizing activity

Integrating mental health support with routine care is essential for people with congenital heart defects

Community area's death rate from heart disease decreases along with decline in violent crime

Long-established drug for angina pectoris shows anti-inflammatory effect, reduces atherosclerotic plaques

Study finds SARS-CoV-2 transmission in children and adolescents is lower than adults

Children born to mothers with PCOS have increased risk of developing childhood illnesses

Researchers may be one step closer to preventing Type 1 diabetes

People with non-alcoholic fatty liver disease may have higher risk of dementia

New chemical biological tools could help better understand the progression of Parkinson's disease

Study describes biochemical pathway that leads to inflammation characteristic of autoimmune diseases

Geisinger researchers receive two grants to study risk factors linked with familial hypercholesterolemia

New center aims to accelerate research into biomarkers of neurodegenerative diseases

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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