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Persistence of SARS-CoV-2 in tissues leads to long COVID

PASC is likely the result of long-term persistence of SARS-CoV-2 in various tissues

11 Jul 2022

Researchers create a comprehensive map of how complex networks of genes function together

Using new technologies to study thousands of genes simultaneously within immune cells, researchers at Gladstone Institutes, UC San Francisco (UCSF), and Stanford School of Medicine have created the most detailed map yet of how complex networks of genes function together.

11 Jul 2022

Researchers receive $3.25 million NIH grant to better understand the oral manifestations of HIV

Researchers at the Case Western Reserve University School of Dental Medicine will use a $3.25 million grant from the National Institutes of Health (NIH) to better understand how HIV impacts the human body, from mouth lesions to oral cancer.

11 Jul 2022

Nuclear stress testing can help shape physicians' decision to refer patients for heart procedures

Patients identified by nuclear stress testing as having severe stress-induced myocardial ischemia (lack of blood flow to the heart) are likely to benefit from heart bypass surgery or angioplasty, while those with mild or no ischemia are not, according to a new study from the Icahn School of Medicine at Mount Sinai.

11 Jul 2022

Black individuals may be more vulnerable to atherosclerosis early in life than young Hispanic adults

A unique Mount Sinai study focused on a multi-ethnic, underserved community in New York City shows that young Black adults are twice as likely to have atherosclerosis as similarly situated young Hispanic adults.

11 Jul 2022

NIH launches clinical trial evaluating an experimental vaccine to prevent Nipah virus infection

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has launched an early-stage clinical trial evaluating an investigational vaccine to prevent infection with Nipah virus.

11 Jul 2022

Pulse oximeter inaccuracies may be associated with racial disparities in care

For most patients, a pulse oximeter is a familiar device from visits to the doctor's office. Placed on a finger or a patient's ear lobe, pulse oximeters are an easy way to quickly get a measure of someone's oxygen saturation (SpO2), which should generally be above 90 percent.

11 Jul 2022

Activation of the STING pathway could help make glioblastoma multiforme more susceptible to immunotherapy

Immunotherapy has revolutionized treatment for many forms of cancer, but glioblastoma multiforme (GBM), the most common and deadly form of brain cancer, has remained untouched.

11 Jul 2022

Researchers identify substantial lack of racial and ethnic data in studies of rare genetic disorder

In a review of published research papers, investigators from the Johns Hopkins Medicine Hereditary Hemorrhagic Telangiectasia Center have identified a substantial lack of racial and ethnic data that may be negatively impacting the treatment and diagnosis of this rare disorder in diverse patients.

11 Jul 2022

Study reveals sex-based differences in the clinical outcomes of COVID-19 in the US

Researchers investigated sex-based differences among COVID-19 patients in the United States.

11 Jul 2022

Adding salt to foods at the table increases risk of premature death

People who add extra salt to their food at the table are at higher risk of dying prematurely from any cause, according to a study of more than 500,000 people, published in the European Heart Journal today (Monday).

9 Jul 2022

In America, cancer patients endure debt on top of disease

Jeni Rae Peters would make promises to herself as she lay awake nights after being diagnosed with breast cancer two years ago.

9 Jul 2022

Researchers discover the first effective drug to treat rare, genetic liver disease

Researchers at Saint Louis University's School of Medicine, in collaboration with Arrowhead Pharmaceuticals and Takeda Pharmaceuticals, report the first effective drug to treat a rare, genetic liver disease that formerly could only be treated with a liver transplant.

8 Jul 2022

Using data via a dashboard to decrease the use of pRBC transfusions and increase appropriate use

In a new paper, researchers from University Hospitals (UH) detail how they used data via a dashboard to decrease the use of packed red-blood cell (pRBC) transfusions and platelets with an increase in appropriate transfusions.

8 Jul 2022

First biohybrid model of human ventricles is an important step forward for organ biofabrication

Heart disease - the leading cause of death in the U.S. - is so deadly in part because the heart, unlike other organs, cannot repair itself after injury.

8 Jul 2022

Clinical trial examining the combination of atezolizumab and chemoradiation for patients with limited-stage SCLC reaches accrual

The NRG Oncology/Alliance clinical trial NRG-LU005, examining the addition of the immunotherapy drug atezolizumab combined with chemoradiation for patients with limited-stage small cell lung cancer (SCLC) recently reached the trial's accrual goal of 506 patients.

8 Jul 2022

Blood News and Research

Persistence of SARS-CoV-2 in tissues leads to long COVID

Researchers create a comprehensive map of how complex networks of genes function together

Researchers receive $3.25 million NIH grant to better understand the oral manifestations of HIV

Nuclear stress testing can help shape physicians' decision to refer patients for heart procedures

Black individuals may be more vulnerable to atherosclerosis early in life than young Hispanic adults

NIH launches clinical trial evaluating an experimental vaccine to prevent Nipah virus infection

Pulse oximeter inaccuracies may be associated with racial disparities in care

Activation of the STING pathway could help make glioblastoma multiforme more susceptible to immunotherapy

Researchers identify substantial lack of racial and ethnic data in studies of rare genetic disorder

Study reveals sex-based differences in the clinical outcomes of COVID-19 in the US

Adding salt to foods at the table increases risk of premature death

In America, cancer patients endure debt on top of disease

Researchers discover the first effective drug to treat rare, genetic liver disease

Using data via a dashboard to decrease the use of pRBC transfusions and increase appropriate use

First biohybrid model of human ventricles is an important step forward for organ biofabrication

Clinical trial examining the combination of atezolizumab and chemoradiation for patients with limited-stage SCLC reaches accrual

Moffitt researchers discover kidney cancer-specific splicing variant biomarkers

Moffitt researchers discover how YAP1 protein contributes to angiogenesis in cancers

Commercial antibodies do not recognize immune receptor ACKR1

The strength and breadth of antibody responses elicited by hybrid immunity to COVID-19 vaccination or infection alone

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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