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CAR T therapy can lead to long-lasting remissions in patients with r/r diffuse large B-cell lymphoma

In an update to a global clinical trial stretching from Philadelphia to four continents, the chimeric antigen receptor (CAR) T cell therapy Kymriah (tisagenlecleucel, formerly CTL019) led to long-lasting remissions in patients with relapsed/refractory (r/r) diffuse large B-cell lymphoma (DLBCL).

3 Dec 2018

Despite reduction in twin stillbirth rates, there is no change in still birth rates involving single fetus

A leading expert in fetal medicine at the University of Birmingham has warned that there is 'little room for complacency' over a fall in twin stillbirth rates as the reason for this phenomenon are complex.

30 Nov 2018

FDA approves new drug for treatment of rare autoimmune disorder

The U.S. Food and Drug Administration today approved Firdapse (amifampridine) tablets for the treatment of Lambert-Eaton myasthenic syndrome (LEMS) in adults.

29 Nov 2018

Study finds 'alarmingly low' prevalence of metabolic health in American adults

The prevalence of metabolic health in American adults is 'alarmingly low,' even among people who are normal weight, according to a new study from the University of North Carolina at Chapel Hill's Gillings School of Global Public Health.

29 Nov 2018

New findings provide clues about neural circuitries that facilitate or undermine adaptation

Neighborhood violence has been associated with adverse health effects on youth, including sleep loss, asthma and metabolic syndrome. Yet some youth living in high-crime neighborhoods manage to avoid these effects.

29 Nov 2018

First biosimilar approved by FDA for treatment of adult patients with non-Hodgkin’s lymphoma

The U.S. Food and Drug Administration today approved Truxima (rituximab-abbs) as the first biosimilar to Rituxan (rituximab) for the treatment of adult patients with CD20-positive, B-cell non-Hodgkin's lymphoma (NHL) to be used as a single agent or in combination with chemotherapy.

29 Nov 2018

New study solves longstanding mystery in innate immunity

UT Southwestern biochemist and Breakthrough Prize winner Dr. Zhijian "James" Chen's newest study answers a long-standing question in the field of innate immunity.

29 Nov 2018

Study estimates economic impact of fetal alcohol spectrum disorder

Fetal alcohol spectrum disorder is a common condition with a high economic impact in both children and adults, concludes an updated review in the Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine.

29 Nov 2018

Second ACC Asia Conference to be held in Shanghai from November 30 to December 2, 2018

The American College of Cardiology will host the second ACC Asia Conference in Shanghai in collaboration with the China Cardiovascular Association and China Heart House from Nov. 30 - Dec. 2, 2018, bringing together top experts to discuss and review new, relevant cardiovascular science pertinent to the region.

29 Nov 2018

Prevalence of metabolic health found to be very low among American adults

A new study found that the prevalence of metabolic health is very low among American adults, even among those who have normal weight.

28 Nov 2018

NIH-funded study finds how hantaviruses infect the lungs

A human protein associated with asthma is key to how hantaviruses infect the lungs and sometimes cause a life-threatening pulmonary condition known as hantavirus pulmonary syndrome, according to researchers supported by the National Institutes of Health.

26 Nov 2018

Home blood pressure checks are more accurate than office BP assessments

Doctors could improve the care of high blood pressure by relying more on home blood pressure checks and not so much on the less-accurate office BP assessments, wrote health care quality experts from The University of Texas Health Science Center at Houston in an editorial in the journal JAMA.

26 Nov 2018

Gut-directed hypnotherapy may offer new treatment option for IBS patients

Gut-directed hypnotherapy delivered by psychologists appears as effective in group or individual sessions, potentially offering a new treatment option for irritable bowel syndrome in primary and secondary care.

23 Nov 2018

MERS virus that causes harmless cold in camels can be fatal for humans

What causes only a harmless cold in camels can be fatal for humans: an infection with the MERS virus. Since its discovery in 2012, the virus was detected in approximately 2,000 patients and 36 percent of them have not survived the severe lung disease known as MERS.

22 Nov 2018

Scientists identify key protein involved in Hantavirus Pulmonary Syndrome

A global team of investigators has identified a key protein involved in Hantavirus Pulmonary Syndrome, a serious and sometimes fatal respiratory disease, according to research published today in the journal Nature.

22 Nov 2018

Study highlights need for better screening tools to detect maternal sepsis

A woman lies in her hospital bed. Her heart rate is elevated, she has a slight fever and an elevated white blood cell count.

21 Nov 2018

UH pharmaceutical scientist developing new drug to treat children with rare genetic disorder

A University of Houston pharmaceutical scientist is developing a new drug which could bring relief to children suffering with Familial Adenomatous Polyposis, a rare genetic disorder characterized by hundreds - if not thousands - of colorectal polyps.

21 Nov 2018

Genetic therapy may help children with Angelman syndrome to overcome seizures

Angelman syndrome is a genetic disease with no cure. Children grow up with severe intellectual disabilities and a range of other problems, arguably the worst of which are epileptic seizures. Now scientists at the UNC School of Medicine have found evidence that genetic therapy may prevent the enhanced seizure susceptibility.

21 Nov 2018

Study uncovers new mechanism controlling the master cancer regulator

Of the more than 23,000 genes in the human genome, only a handful assume a very central role in signal transduction and growth regulation. Of these, the three genes encoding RAS proteins are particularly important, as they are found mutated in over 25% of human cancers.

20 Nov 2018

Live probiotics can change existing gut flora and alter immune response

New research published in the International Journal of Pharmaceutics demonstrates that 'good' bacteria in the live probiotic SymproveTM can successfully reach and colonize the gut, where they go on to change the existing gut flora. They are also capable of modifying immune response.

20 Nov 2018