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Rare Cells Capable of Transforming into Leukemia may Provide new Insight into Leukemic Landscape

In our latest interview, News Medical speaks to Adam G. Schrum, PhD, Associate Professor of Molecular Microbiology & Immunology and Surgery at the University of Missouri, about how dysfunction in an unusual type of thymocyte cell may develop into leukemia in some patients.

8 Jul 2022

Smoking cigarettes while wearing a mask may impair blood vessel function

Smoking traditional or non-combustible cigarettes while wearing a surgical mask results in a two-fold rise in exhaled carbon monoxide and impaired blood vessel function compared to non-mask periods.

8 Jul 2022

Diabetes not strongly associated with in-hospital COVID mortality

In a recent study posted to the medRxiv* preprint server, researchers assessed the association between diabetes mellitus (type 2 diabetes) and mortality among patients hospitalized with coronavirus disease 2019 (COVID-19) at multiple centers in Canada and Denmark.

8 Jul 2022

After 3 doses of COVID vaccine, most cancer patients retain detectable humoral immunity

In a recent study posted to the medRxiv* preprint server, researchers assessed the efficacy and durability of immune responses to the third dose of coronavirus disease 2019 (COVID-19) vaccines. They also assessed the efficacy of the fourth vaccine dose among severely immunocompromised patients with hematological malignancies.

7 Jul 2022

Diabetes patients on Medicare Advantage plans less likely to be prescribed newer, more expensive medicines

While patients with diabetes on Medicare Advantage plans are more likely to receive preventive treatments, they were less likely to be prescribed newer, more expensive medications and were more likely to have higher blood pressure and worse blood glucose control than patients on Medicare Fee-For-Service plans, according to a new study led by a University of Pittsburgh School of Medicine physician-scientist.

7 Jul 2022

Chronic stress in pregnancy affects fetal iron homeostasis

If a woman experiences chronic stress late in her pregnancy, it can affect her fetus' ability to absorb iron by as much as 15%, according to a study led by UW Medicine researchers in Seattle.

7 Jul 2022

Study identifies chromosomal abnormalities associated with relapse in frequent subtype of childhood B-ALL

An international research team coordinated by Dr. Oscar Molina and Dr. Pablo Menéndez, from the Josep Carreras Leukaemia Research Institute, identifies chromosomal abnormalities associated to relapse in a frequent subset of B-cell Acute Lymphoblastic Leukemia (B-ALL), a severe condition affecting especially children.

7 Jul 2022

Novel COVID-19 antibody delivery approach advances to clinical trials

Under a Defense Advanced Research Projects Agency (DARPA) and Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense (JPEO-CBRND) funded program, a novel COVID-19 antibody delivery approach has advanced to clinical trials.

7 Jul 2022

New biosensor system derived from E. coli bacteria could accelerate drug development

For more affordable, sustainable drug options than we have today, the medication we take to treat high blood pressure, pain or memory loss may one day come from engineered bacteria, cultured in a vat like yogurt.

7 Jul 2022

Paternal phenotypic, lifestyle characteristics do not play a role in preeclampsia susceptibility of their partners

Preeclampsia - a condition that occurs in pregnancy and is characterized by high blood pressure and signs of kidney damage - can be dangerous for both mother and baby.

7 Jul 2022

Low doses of a less commonly used drug may be a better treatment option for gout

Gout occurs when urate crystals accumulate in the joints, and xanthine oxidase inhibitors such as febuxostat are a mainstay of therapy to help reduce blood urate levels in affected patients.

7 Jul 2022

Novel gene-based therapies for sickle cell disease rely on finding the right mouse for the job

Sickle cell disease is an extremely debilitating condition that affects up to 40% of the population in African countries, with patients suffering episodes of excruciating pain, organ damage and reduced life-expectancy.

7 Jul 2022

Risk factors associated with shoulder surgery are low, but some need further surgery within a year

Rates of serious complications associated with shoulder surgery are low, but one in 26 patients need further surgery within a year, finds a study in The BMJ today.

7 Jul 2022

Researchers find a way to kill recurring prostate cancer with a lot of iron

Prostate cancer can come back from common hormone deprivation therapy with a vengeance and no clear treatment option, but scientists have early evidence that one way to kill these recurring cancer cells may be with a lot of iron.

7 Jul 2022

Study examines IMPACC trial results to understand clinical phenotypes of disease severity in hospitalized COVID-19 patients

In a recent article, longitudinal clinical phenotypes were described based on respiratory ordinal scales.

7 Jul 2022

COVID-19 and brain damage explained

In a recent study published in the Brain journal, researchers in the United States analyzed the neurovascular injury in coronavirus disease 2019 (COVID-19).

7 Jul 2022

The role of myostatin in female fertility

A new study discusses some of the key functions of myostatin in female reproductive health and disease.

6 Jul 2022

$3.1 million grant will help researchers to study signs of heart damage in young breast cancer survivors

A 5-year, $3.1 million grant from the National Heart, Lung and Blood Institute, part of the National Institutes of Health, will enable researchers from Atrium Health Wake Forest Baptist's NCI-designated Comprehensive Cancer Center, Virginia Commonwealth University Massey Cancer Center and Duke Cancer Institute to collaborate in a first-of-its-kind prospective study to look for the earliest signs of heart vessel damage in young, pre-menopausal breast cancer survivors.

6 Jul 2022

Damon Runyon Cancer Research Foundation names five new Damon Runyon Clinical Investigators

The Damon Runyon Cancer Research Foundation has named five new Damon Runyon Clinical Investigators.

6 Jul 2022

Noradrenergic drugs could be repurposed to offer effective treatment for Alzheimer's disease symptoms

There is "good evidence" that drugs to treat attention deficit hyperactivity disorder (ADHD) might also successfully treat key aspects of Alzheimer's disease, finds a pooled data analysis of the available research, published online in the Journal of Neurology Neurosurgery & Psychiatry.

6 Jul 2022

Blood News and Research

Rare Cells Capable of Transforming into Leukemia may Provide new Insight into Leukemic Landscape

Smoking cigarettes while wearing a mask may impair blood vessel function

Diabetes not strongly associated with in-hospital COVID mortality

After 3 doses of COVID vaccine, most cancer patients retain detectable humoral immunity

Diabetes patients on Medicare Advantage plans less likely to be prescribed newer, more expensive medicines

Chronic stress in pregnancy affects fetal iron homeostasis

Study identifies chromosomal abnormalities associated with relapse in frequent subtype of childhood B-ALL

Novel COVID-19 antibody delivery approach advances to clinical trials

New biosensor system derived from E. coli bacteria could accelerate drug development

Paternal phenotypic, lifestyle characteristics do not play a role in preeclampsia susceptibility of their partners

Low doses of a less commonly used drug may be a better treatment option for gout

Novel gene-based therapies for sickle cell disease rely on finding the right mouse for the job

Risk factors associated with shoulder surgery are low, but some need further surgery within a year

Researchers find a way to kill recurring prostate cancer with a lot of iron

Study examines IMPACC trial results to understand clinical phenotypes of disease severity in hospitalized COVID-19 patients

COVID-19 and brain damage explained

The role of myostatin in female fertility

$3.1 million grant will help researchers to study signs of heart damage in young breast cancer survivors

Damon Runyon Cancer Research Foundation names five new Damon Runyon Clinical Investigators

Noradrenergic drugs could be repurposed to offer effective treatment for Alzheimer's disease symptoms

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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