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Depletion of reactive astrocytes regresses glioblastoma

A groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cancer. The researchers achieved the outcome using a method they developed based on their discovery of two critical mechanisms in the brain that support tumor growth and survival: one protects cancer cells from the immune system, while the other supplies the energy required for rapid tumor growth. The work found that both mechanisms are controlled by brain cells called astrocytes, and in their absence, the tumor cells die and are eliminated.

2 Sep 2022

Study provides a comprehensive view of the genomics of all childhood ALL subtypes

Scientists have created a roadmap of the genetic mutations present in the most common childhood cancer, acute lymphoblastic leukemia (ALL).

1 Sep 2022

New method combines zero- to ultralow-field NMR with special hyperpolarization technique for detection of alcohols

Nuclear magnetic resonance (NMR) is an analytical tool with a wide range of applications, including the magnetic resonance imaging that is used for diagnostic purposes in medicine.

1 Sep 2022

Integrating recent advances in multi-omics tumor profiling into precision cancer treatment

Tumors have significant differences depending on the person affected, even if they are the same cancer, such as breast cancer.

1 Sep 2022

New substance boosts the effect of protein-based COVID-19 vaccines

Ironically, some vaccines need their own "boosters." Adding an ingredient called an adjuvant can help vaccines elicit a more robust immune response, better training the body to fight a pathogen.

1 Sep 2022

Study opens a window of opportunity to design RAF1 degraders against lung adenocarcinomas

One of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes -genes that cause cancer when mutated - are responsible for a quarter of all human cancers, including the three tumor types with the highest mortality rates: lung adenocarcinoma, colorectal carcinoma and pancreatic ductal adenocarcinoma.

1 Sep 2022

Researchers identify how some cancer cells cheat treatment-induced cell death

Scientists at St. Jude Children's Research Hospital have identified how some cancer cells cheat treatment-induced cell death.

1 Sep 2022

New kind of synapse discovered in neurons’ tiny hairs

Scientists at HHMI's Janelia Research Campus have discovered a new kind of synapse in the tiny hairs on the surface of neurons.

1 Sep 2022

KU Leuven scientists create a new type of human cell in the lab using stem cells

Professor Vincent Pasque and his team at KU Leuven have managed to generate a new type of human cell in the lab using stem cells. The new cells closely resemble their natural counterparts in early human embryos.

1 Sep 2022

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Researchers at Sanford Burnham Prebys, led by Ze'ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth.

1 Sep 2022

Simple blood test may identify patients at high risk of neurotoxic complications after CAR-T cell therapy

Cell-based immunotherapy called CAR-T cell therapy has revolutionized the treatment of several cancers.

1 Sep 2022

Study shows encouraging therapeutic options for patients with relapsed multiple myeloma

Mount Sinai researchers have published results that show encouraging therapeutic options for patients with the blood cancer multiple myeloma after first-line treatment with bispecific antibodies fails.

1 Sep 2022

Researchers demonstrate improved culture of primate induced pluripotent stem cells

The following study transplanted iPSCs derived from two NHP species, chimpanzee and pigtailed macaque, into blastocysts from another NHP species – the rhesus macaque.

1 Sep 2022

Less is more: early short-course rapamycin effective in sustained anti-aging effects

A new study shows that a brief treatment period could have the same anti-aging efficacy and duration of effect but without the potentially serious adverse effects of chronic administration.

1 Sep 2022

Molecular fate-mapping of antibodies shows effects of antigenic imprinting

In a new study, researchers developed a molecular fate-mapping method for differential detection of antibodies derived from specific B cell clones.

1 Sep 2022

How does origin impact antiviral immune response?

A new study observed differential antiviral responses in Indian and European individuals.

1 Sep 2022

Cell Counting Without Slides to Reduce Waste and Cost

Until recently, cells were typically counted on a reusable quartz hemocytometer.

From DeNovix Inc. 1 Sep 2022

dsDNA Quantification for NGS Quality Control

Andrew Jones discusses the importance of quality control in NGS and the effect that a poorly followed protocol can have on experimental results.

From DeNovix Inc. 1 Sep 2022

The currently available evidence on viral-induced parkinsonism

A new review attempts to summarize all known about the relationship between viral illness and parkinsonian disorders to facilitate further research.

31 Aug 2022

The most recent evidence about phylogenesis, pathogenesis, prevention, and treatment for monkeypox

A new review sheds light on the origins of this virus and recently acquired knowledge about its disease mechanism and the preventive and therapeutic measures appropriate in this situation.

31 Aug 2022

Cell News and Research

Depletion of reactive astrocytes regresses glioblastoma

Study provides a comprehensive view of the genomics of all childhood ALL subtypes

New method combines zero- to ultralow-field NMR with special hyperpolarization technique for detection of alcohols

Integrating recent advances in multi-omics tumor profiling into precision cancer treatment

New substance boosts the effect of protein-based COVID-19 vaccines

Study opens a window of opportunity to design RAF1 degraders against lung adenocarcinomas

Researchers identify how some cancer cells cheat treatment-induced cell death

New kind of synapse discovered in neurons’ tiny hairs

KU Leuven scientists create a new type of human cell in the lab using stem cells

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Simple blood test may identify patients at high risk of neurotoxic complications after CAR-T cell therapy

Study shows encouraging therapeutic options for patients with relapsed multiple myeloma

Researchers demonstrate improved culture of primate induced pluripotent stem cells

Less is more: early short-course rapamycin effective in sustained anti-aging effects

Molecular fate-mapping of antibodies shows effects of antigenic imprinting

How does origin impact antiviral immune response?

Cell Counting Without Slides to Reduce Waste and Cost

dsDNA Quantification for NGS Quality Control

The currently available evidence on viral-induced parkinsonism

The most recent evidence about phylogenesis, pathogenesis, prevention, and treatment for monkeypox

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics