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Exploring the use of chest CT-based imaging biomarkers for early-stage COVID-19 screening

In a new study, researchers demonstrated that vasculature-like signals (N) in chest computed tomography (CT) scans could serve as robust imaging biomarkers (IBs) of early-stage COVID-19 screening.

14 Oct 2022

Study presents rare cases of COVID-19-associated pulmonary aspergillosis

Researchers presented a case series of patients with coronavirus disease 2019 (COVID-19)-associated pulmonary aspergillosis (CAPA). The goal of the study was to inform clinicians and healthcare workers of this serious COVID-19-related complication.

14 Oct 2022

Study describes the first SARS-CoV-2 Deltacron recombinant case identified in Brazil

Researchers demonstrated the parallel evolution of the SARS-CoV-2 Deltacron variant.

14 Oct 2022

Mouse model reveals how RNA splicing defects contribute to neurodegeneration in Alzheimer's disease

Researchers have puzzled over the neurodegenerative disorder Alzheimer's disease for decades, but treatments to stop or reverse the disease's effects on the brain have remained elusive.

13 Oct 2022

Study finds memory B cell clones harbor the capacity to adopt multiple and functionally different fates in COVID-19 patients

Researchers examined single clones of SARS-CoV-2-specific memory B cells to understand their adaptability and fate.

13 Oct 2022

Novel method deploys nanopore tweezers to facilitate inhibition of SARS-CoV-2 helicase at single-nucleotide resolution

In a new study, researchers visualized the mechanism of action and inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 13 (NSP13) at high spatio-temporal resolution.

13 Oct 2022

Researchers develop an HERV-enveloped recombinant baculoviral DNA vaccine against SARS-CoV-2

Researchers developed a human endogenous retrovirus (HERV)-enveloped recombinant baculoviral DNA vaccine to target the SARS-CoV-2 Delta variant, and tested its cross-protection efficacy using mice models.

13 Oct 2022

Evaluating SARS-CoV-2 rapid antigen tests using saliva specimen

In a new study, researchers evaluated a rapid antigen test (RAT) that used saliva specimens to detect the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

13 Oct 2022

What is the association between interferon genes and complement regulatory protein expressions in SARS-CoV-2 infections?

Researchers investigated the expression of complement regulatory proteins (CRPs) in coronavirus disease 2019 (COVID-19) to identify potential dysregulated CRP patterns and investigate whether they contribute to COVID-19 pathogenesis.

13 Oct 2022

Scientists show how cellular hypoxia response increases fetal hemoglobin expression in adults

Scientists at St. Jude Children's Research Hospital have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased expression of fetal hemoglobin (HbF) in adults.

12 Oct 2022

Study explores cell signaling dysregulation and COVID-19 severity

Researchers assessed the impact of dysregulation in cell signaling events on coronavirus disease 2019 (COVID-19) severity.

12 Oct 2022

Researchers develop a causal model to assess the dependence of viral loads of patients infected with COVID-19 on age

Researchers developed a causal model to analyze SARS-CoV-2 viral load distribution as a function of patients’ age.

12 Oct 2022

The ability of antiviral formulation ViruSAL to inhibit SARS-CoV-2 infectivity

Researchers from Ireland used human bronchial epithelium models to evaluate the ability of a novel proprietary formulation called ViruSAL to inhibit SARS-CoV-2 infections.

12 Oct 2022

Researchers report the first RT-qPCR for simultaneous detection and discrimination of Omicron sub-variants

Researchers developed a RT-qPCR system to identify SARS-CoV-2 Omicron variants of concern.

12 Oct 2022

Observational study explores the real-world efficacy of oral antivirals against the SARS-CoV-2 Omicron variant

A new study reported the real-world efficacy of oral antiviral therapies nirmatrelvir plus ritonavir, and molnupiravir on the SARS-CoV-2 Omicron (B.1.1.529) variant, based on an observational study among coronavirus disease 2019 (COVID-19) patients in Hong Kong.

12 Oct 2022

Transcription News and Research

Exploring the use of chest CT-based imaging biomarkers for early-stage COVID-19 screening

Study presents rare cases of COVID-19-associated pulmonary aspergillosis

Study describes the first SARS-CoV-2 Deltacron recombinant case identified in Brazil

Mouse model reveals how RNA splicing defects contribute to neurodegeneration in Alzheimer's disease

Study finds memory B cell clones harbor the capacity to adopt multiple and functionally different fates in COVID-19 patients

Novel method deploys nanopore tweezers to facilitate inhibition of SARS-CoV-2 helicase at single-nucleotide resolution

Researchers develop an HERV-enveloped recombinant baculoviral DNA vaccine against SARS-CoV-2

Evaluating SARS-CoV-2 rapid antigen tests using saliva specimen

What is the association between interferon genes and complement regulatory protein expressions in SARS-CoV-2 infections?

Scientists show how cellular hypoxia response increases fetal hemoglobin expression in adults

Study explores cell signaling dysregulation and COVID-19 severity

Researchers develop a causal model to assess the dependence of viral loads of patients infected with COVID-19 on age

The ability of antiviral formulation ViruSAL to inhibit SARS-CoV-2 infectivity

Researchers report the first RT-qPCR for simultaneous detection and discrimination of Omicron sub-variants

Observational study explores the real-world efficacy of oral antivirals against the SARS-CoV-2 Omicron variant

What is the association of pneumococcal carriage with SARS-CoV-2 infection?

Study offers a systems biology strategy to facilitate the search for effective COVID-19 drugs

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

The role of oxidative stress in congenital syndromes

Metformin reduces risk of severe COVID-19 in diabetic patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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