Dopamine News and Research

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Dopamine is a hormone and neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine has many functions in the brain, including important roles in behavior and cognition, motor activity, motivation and reward, inhibition of prolactin production (involved in lactation), sleep, mood, attention, and learning. Dopaminergic neurons (i.e., neurons whose primary neurotransmitter is dopamine) are present chiefly in the ventral tegmental area (VTA) of the midbrain, substantia nigra pars compacta, and arcuate nucleus of the hypothalamus.
Scientists create new compounds that could slow progression of Parkinson's

Scientists create new compounds that could slow progression of Parkinson's

Medication at end of life indicates care quality

Medication at end of life indicates care quality

Exendin-4 could effectively treat addiction

Exendin-4 could effectively treat addiction

Psychotic reactions associated with natural testosterone booster products

Psychotic reactions associated with natural testosterone booster products

Stem cell study may help to unravel how genetic mutation leads to Parkinson's symptoms

Stem cell study may help to unravel how genetic mutation leads to Parkinson's symptoms

Nonmotor symptoms common in early-stage PD

Nonmotor symptoms common in early-stage PD

Hereditary genes responsible for pain severity after motor vehicle collisions

Hereditary genes responsible for pain severity after motor vehicle collisions

Mephedrone and memory loss: an interview with Craig Motbey

Mephedrone and memory loss: an interview with Craig Motbey

Animal research shows promise in treating AD, brain damage and heart problems resulting from SCIs

Animal research shows promise in treating AD, brain damage and heart problems resulting from SCIs

Mother rats respond much differently to cocaine than non-mothers

Mother rats respond much differently to cocaine than non-mothers

Rapamycin may delay onset of Parkinson's or AD

Rapamycin may delay onset of Parkinson's or AD

GE Healthcare launches new online patient and caregiver resource for Parkinson's disease

GE Healthcare launches new online patient and caregiver resource for Parkinson's disease

Civitas to present CVT-301 Phase 1 study results at Parkinson's Disease Therapeutics Conference

Civitas to present CVT-301 Phase 1 study results at Parkinson's Disease Therapeutics Conference

New insights into how brain responds to extreme stress

New insights into how brain responds to extreme stress

AAPS recognizes top scientists in pharmaceutical sciences

AAPS recognizes top scientists in pharmaceutical sciences

Highlights of Mount Sinai research at Neuroscience 2012

Highlights of Mount Sinai research at Neuroscience 2012

Investigators provide overview of role of dopamine in modulating the immune system

Investigators provide overview of role of dopamine in modulating the immune system

Enrollment complete in Euthymics’ amitifadine phase 2b/3a trial for major depressive disorder

Enrollment complete in Euthymics’ amitifadine phase 2b/3a trial for major depressive disorder

Kynurenic acid levels increased in bipolar patients with psychotic features

Kynurenic acid levels increased in bipolar patients with psychotic features

Translational Genomics Research Institute creates new center for rare childhood disorders

Translational Genomics Research Institute creates new center for rare childhood disorders

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