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Evaluating graphene field effect biosensor for ultraprecise and simultaneous influenza and SARS-CoV-2 detection

In a new study, researchers developed an antibody (Ab)-modified graphene field effect transistor (GFET)-based biosensor for ultraprecise and rapid influenza A virus (IAV) and SARS-CoV-2 protein detection and differentiation.

10 Oct 2022

Study suggests colleagues and household members increase SARS-CoV-2 infection risk in hospital employees, not COVID-19 patients

In a new study, researchers conducted an observational study to assess severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence and infection status among Jena University Hospital (JUH) employees.

10 Oct 2022

NEI researchers create a high-resolution map of retinal cell chromatin contract points

National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell's nucleus.

7 Oct 2022

Study uncovers how the TAZ protein protects hematopoietic stem cells from aging

A well-functioning immune system is essential for protection against infections. However, with increasing age, the functioning of the immune system diminishes, which is also due to age-related damage in hematopoietic (blood) stem cells.

7 Oct 2022

Researchers take new approach to studying the development of the human brain

Researchers at ETH Zurich are growing human brain-like tissue from stem cells and are then mapping the cell types that occur in different brain regions and the genes that regulate their development.

7 Oct 2022

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

Researchers demonstrated that the SARS-CoV-2 protein functions as a histone mimic to disrupt the epigenetic regulation of host cells.

7 Oct 2022

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Researchers established a neonatal mice model that enabled SARS-CoV-2 transmission.

7 Oct 2022

COVID‐19 pathology across different tissues

Researchers investigated COVID-19 pathophysiology in multiple tissues, including the lungs, kidneys, heart, and brain, for a deeper understanding of its acute and long‐term symptoms.

7 Oct 2022

Study suggests an immunological benefit of combining previous natural infection with vaccination against COVID-19 using a combination of different vaccine platforms

Researchers explored SARS-CoV-2-targeted immune responses among COVAC1 participants who received a novel saRNA vaccine followed by the mRNA BNT162b2 vaccine BNT162b2 vaccine, with or without prior COVID-19 history.

7 Oct 2022

Discovery could play an important role in future medicines to heal damaged hearts

Scientists at the UNC School of Medicine have made a significant advance in the promising field of cellular reprogramming and organ regeneration, and the discovery could play a major role in future medicines to heal damaged hearts.

6 Oct 2022

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

In a new study, researchers developed a three-dimensional (3D) in vitro tissue model to assess the effects of SARS-CoV-2 on the vascular endothelial cells.

5 Oct 2022

Key biophysical attributes of a self-amplifying viral RNA vaccine developed for SARS-CoV-2

Researchers used various analytical characterization techniques to determine the biophysical attributes of the Imperial College London self-amplifying viral RNA vaccine (IMP-1) developed for SARS-CoV-2.

5 Oct 2022

Transient cell-in-cell formation by tumor cells found to build resistance to immunotherapy

Researchers demonstrated that tumor cells evade immunotherapy by generating unique transient cell-in-cell structures, resistant to chemotherapy and destruction by T cells.

5 Oct 2022

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

In a new study, researchers determined the 1.8-Å resolution crystal structure of the H1 dual specific phosphatase (DSP) of monkeypox virus (MPXV) that is crucial for viral replication, making it an attractive antiviral target.

5 Oct 2022

What is the COVID-19 mRNA-1273 vaccine effectiveness against SARS-CoV-2 Omicron sub-variants?

Researchers evaluated the messenger ribonucleic acid (mRNA)-1273 vaccine effectiveness against SARS-CoV-2 Omicron sub-variant of concern infections and hospitalizations.

4 Oct 2022

Can you shed infectious SARS-CoV-2 virions even if COVID vaccinated?

Researchers in the United States published a study in the journal PLOS Pathogens that examined the shedding of infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virions despite vaccination against it.

4 Oct 2022

How COVID-19 affects the female reproductive system

A new review in the Biology of Reproduction journal analyzed the relationship between the immune system and the female reproductive system while focusing on the effects of COVID-19-associated immune responses on the reproductive system. The study searched PubMed to identify peer-reviewed literature in English up to May 2022 and finally included 83 studies.

3 Oct 2022

Mount Sinai study suggests significant role of reactive oxygen species in maintaining healthy intestines

Mount Sinai researchers have published one of the first studies to demonstrate the importance of reactive oxygen species in maintaining stem cell function and preventing inflammation during wound repair, which could provide greater insights into the prevention and treatment of inflammatory bowel diseases (IBD), according to findings published in the journal Gut on October 3.

3 Oct 2022

The duration of the infectious stage of individuals infected with the SARS-CoV-2 Omicron variant

Researchers demonstrated clinical features and infectivity of the currently dominant SARS-CoV-2 variant of concern Omicron, compared to Delta, the previously dominant VOC.

3 Oct 2022

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Researchers explored the in vivo efficacy of SARS-CoV-2-encoded proteins against neuromuscular degeneration associated with ribosome stalling.

3 Oct 2022

Transcription News and Research

Evaluating graphene field effect biosensor for ultraprecise and simultaneous influenza and SARS-CoV-2 detection

Study suggests colleagues and household members increase SARS-CoV-2 infection risk in hospital employees, not COVID-19 patients

NEI researchers create a high-resolution map of retinal cell chromatin contract points

Study uncovers how the TAZ protein protects hematopoietic stem cells from aging

Researchers take new approach to studying the development of the human brain

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

COVID‐19 pathology across different tissues

Study suggests an immunological benefit of combining previous natural infection with vaccination against COVID-19 using a combination of different vaccine platforms

Discovery could play an important role in future medicines to heal damaged hearts

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

Key biophysical attributes of a self-amplifying viral RNA vaccine developed for SARS-CoV-2

Transient cell-in-cell formation by tumor cells found to build resistance to immunotherapy

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

What is the COVID-19 mRNA-1273 vaccine effectiveness against SARS-CoV-2 Omicron sub-variants?

Can you shed infectious SARS-CoV-2 virions even if COVID vaccinated?

How COVID-19 affects the female reproductive system

Mount Sinai study suggests significant role of reactive oxygen species in maintaining healthy intestines

The duration of the infectious stage of individuals infected with the SARS-CoV-2 Omicron variant

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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