in vitro News and Research

RSS

Novel technology enhances potency and breadth of vaccine-induced responses through antigen presentation

Novel EABR technology enhances potency and breadth of vaccine-induced responses through antigen presentation.

30 May 2023

Energy drinks may stunt muscle repair, new study suggests

Energy drinks impede muscle regeneration and reduce physical performance. This study provided evidence of an inhibitory effect on myogenic differentiation and highlighted potential concerns for athletes and fitness enthusiasts.

29 May 2023

Novel assay for identifying individuals with synucleinopathies using serum samples

Synucleinopathies are a group of neurodegenerative diseases caused by the abnormal accumulation α-synuclein, a protein normally found in the brain and neurons. Incorrect folding of α-synuclein leads to formation of 'seeds', which attract more α-synuclein proteins to form larger clumps.

29 May 2023

World’s first childbirth following a uterus transplantation achieved solely by robot-assisted surgery

For the first time worldwide, in yet another breakthrough by the world-leading research team at the University of Gothenburg, a child has been born following a uterus transplantation achieved solely by robot-assisted surgery on both donor and recipient.

26 May 2023

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2.

26 May 2023

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

A new research paper was published in Oncotarget's Volume 14 on May 19, 2023, entitled, "G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis."

23 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Newly discovered molecule effectively destroys senescent cells

Over time, the body's cells stop working properly and begin to accumulate, which eventually leads to tissues aging.

22 May 2023

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

Research describes the development of a synthetic delivery vector called STxB for mucosal vaccination. It induces mucosal immunity, including resident memory CD8+ T cells and IgA antibodies, against antigens derived from mucosal viruses when administered intranasally in mice.

21 May 2023

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Researchers derived peptides from the SARS-CoV-2 spike protein to assess COVID-19-associated inflammatory changes using zebrafish models.

19 May 2023

Researchers find that SARS-CoV-2 directly infects hepatocytes that cause hyperglycemia

Researchers investigate whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused hyperglycemia.

18 May 2023

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

A pair of internationally renowned stem cell cloning experts at the University of Houston is reporting their findings of variant cells in the lungs of patients with Idiopathic Pulmonary Fibrosis (IPF) which likely represent key targets in any future therapy for the condition.

17 May 2023

HER2-TPMC proves to be a reasonable alternative for HER2-positive cancer chemotherapeutics

Announcing a new article publication for BIO Integration journal. Antibody-drug conjugates (ADCs) have the following advantages: target specificity; wide therapeutic index; and prolonged circulation half-life.

15 May 2023

New compound with antibacterial activity shows promising results within one hour in laboratory trials

Resistance to antibiotics is a problem that alarms the medical and scientific community. Bacteria resistant to three different classes of antibiotics, known as multi-drug resistant (MDR) bacteria, are far from rare.

15 May 2023

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Researchers discuss the use of endo-lysosome-targeted nanoparticles for delivering antiviral therapy to treat coronavirus infections.

15 May 2023

Supercharge your health with carotenoids

This review highlights carotenoids' various biological activities, including antioxidant, anti-tumor, anti-diabetic, anti-aging, and anti-inflammatory effects, with a specific focus on lycopene.

15 May 2023

Study suggests that vitamin C and dietary nitrate could be promising in improving endothelial function and reducing cardiovascular disease risk

Researchers discussed the role of vitamin C and dietary nitrate in endothelial function (EF).

12 May 2023

Consuming ultra-processed foods is associated with an increased risk of developing non-alcoholic fatty liver disease

Researchers determined the contribution of ultra-processed food intake to the risk of developing NAFLD.

12 May 2023

How eating mushrooms may lower blood pressure levels

Scientists review the potential of edible mushrooms as functional foods in improving cardiovascular function and ameliorating hypertension.

11 May 2023

in vitro News and Research

Novel technology enhances potency and breadth of vaccine-induced responses through antigen presentation

Energy drinks may stunt muscle repair, new study suggests

Novel assay for identifying individuals with synucleinopathies using serum samples

World’s first childbirth following a uterus transplantation achieved solely by robot-assisted surgery

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Newly discovered molecule effectively destroys senescent cells

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Researchers find that SARS-CoV-2 directly infects hepatocytes that cause hyperglycemia

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

HER2-TPMC proves to be a reasonable alternative for HER2-positive cancer chemotherapeutics

New compound with antibacterial activity shows promising results within one hour in laboratory trials

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Supercharge your health with carotenoids

Study suggests that vitamin C and dietary nitrate could be promising in improving endothelial function and reducing cardiovascular disease risk

Consuming ultra-processed foods is associated with an increased risk of developing non-alcoholic fatty liver disease

How eating mushrooms may lower blood pressure levels

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News