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Modifi Bio comes up with a new technology to combat cancer cells with DNA modification

Modifi Biosciences announced today that the journal Science has published a critical study validating the company's novel oncology platform based on new classes of molecules that exploit tumor-associated DNA repair defects through direct cancer cell DNA modification.

29 Jul 2022

New glioma drug may represent a paradigm for designing therapeutics exploiting specific DNA repair

A new class of glioma drugs exploits tumors that lack the DNA repair enzyme MGMT; the drugs lead to the generation of cytotoxic DNA and selectively kill tumor cells without the risk of resistance, researchers report.

29 Jul 2022

Study uncovers the crucial roles of kinesins during the malaria parasite life cycle

Scientists at the University of Nottingham have made a major breakthrough in understanding how malaria parasites divide and transmit the disease, which could be a major step forwards in helping to prevent one of the biggest killer infections in the world.

29 Jul 2022

New breakthrough shows antimicrobial resistance is more evolved than previously recognized

Researchers have discovered a significant and previously unknown mechanism that many bacteria use to resist antibiotics.

29 Jul 2022

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Of the roughly 20,000 people in the U.S. diagnosed with esophageal cancer this year, just 4,000 are likely to still be alive in 2027.

28 Jul 2022

Study highlights impaired ketogenesis as a potential confounder of severe COVID-19

In severe Covid-19 patients, the metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order to fight the virus effectively.

28 Jul 2022

New method for organoid production could help advance research studies

As the idea of growing tiny human organs in lab dishes has moved in recent years from futuristic science fiction to actual bioscientific reality, the usefulness of organoids as a research tool for studying the digestive system swiftly encountered a bottleneck - these valuable tissues are quite difficult to make.

28 Jul 2022

New bacteria-killing copper coating could reduce infections from high-touch surfaces

A new copper coating that kills bacteria quicker and in greater amounts than current formulations could soon be available for hospitals and other high-traffic facilities.

28 Jul 2022

The bat-virus relationship examined

A new study examines the role of bats as reservoirs of several viruses and the factors that contribute to the emergence of these viruses.

28 Jul 2022

TMPRSS2 protein, a novel target for SARS-CoV-2 drugs

A new study reports the activity of a compound which inhibited TMPRSS2, ultimately preventing severe COVID-19.

28 Jul 2022

Cross-reactive SARS-CoV-2 antibodies after exposure to avian coronavirus vaccine

Researchers identify SARS-CoV-2 cross-reactive antibodies in poultry farm workers exposed to the avian infectious bronchitis virus.

28 Jul 2022

Newly developed nanobody can get through tough brain cells and treat Parkinson’s disease

Proteins called antibodies help the immune system find and attack foreign pathogens. Mini versions of antibodies, called nanobodies - natural compounds in the blood of animals such as llamas and sharks - are being studied to treat autoimmune diseases and cancer.

28 Jul 2022

Cell News and Research

Modifi Bio comes up with a new technology to combat cancer cells with DNA modification

New glioma drug may represent a paradigm for designing therapeutics exploiting specific DNA repair

Study uncovers the crucial roles of kinesins during the malaria parasite life cycle

New breakthrough shows antimicrobial resistance is more evolved than previously recognized

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Study highlights impaired ketogenesis as a potential confounder of severe COVID-19

New method for organoid production could help advance research studies

New bacteria-killing copper coating could reduce infections from high-touch surfaces

The bat-virus relationship examined

TMPRSS2 protein, a novel target for SARS-CoV-2 drugs

Cross-reactive SARS-CoV-2 antibodies after exposure to avian coronavirus vaccine

Newly developed nanobody can get through tough brain cells and treat Parkinson’s disease

Study reveals a direct connection between the vagus nerve and learning centers of the brain

Novel targeted therapy may be an effective treatment option for neuroblastoma

New imaging technique reveals subtle details about pathology in a rare eye disease

New discovery may open the door to targeted treatments for two types of rhabdomyosarcoma

The identification and characterization of an anti-SARS-CoV-2 monoclonal antibody with superior breadth and potency

The effect of Artemisia annua hot water extracts against the SARS-CoV-2 Omicron variant

COVID-19 Moderna vaccine induces significant antibody reactions among children

Researchers find adeno-associated virus 2 infection in children with hepatitis of unknown etiology

What are the challenges of cell line development? eBook

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Designing fluidic architecture for scalable diagnostic platforms

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