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Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes

Immune reactions are usually a good thing - the body's way of eliminating harmful bacteria and other pathogens. But people also rely on molecular "brakes," or checkpoints, to keep immune systems from attacking their own cells and organs and causing so-called autoimmune disease.

29 Aug 2018

New study supports motor cortex 'excitability' as cause of restless legs syndrome

Johns Hopkins Medicine researchers say new experiments using magnetic pulse brain stimulation on people with moderate to severe restless legs syndrome have added to evidence that the condition is due to excitability and hyperarousal in the part of the brain's motor cortex responsible for leg movement.

29 Aug 2018

Researchers receive $6 million NIH grant to improve treatment for Chagas disease

Scientists at The University of Texas at El Paso have received nearly $6 million from the National Institutes of Health to improve treatment and develop new diagnostic tools to assess post-therapeutic outcomes for patients with Chagas disease.

29 Aug 2018

Hurricane Maria’s official death toll in Puerto Rico now stands at nearly 3,000

Nearly 3,000 Puerto Ricans died as a result of the devastation caused by Hurricane Maria last year, a number that dwarfs the government's initial tally of 64, according to a report commissioned by Puerto Rican officials and released Tuesday.

29 Aug 2018

Researchers discover mechanism that steers growth of cancer cells in melanoma and liver cancer

Melanoma and liver cancer are becoming more widespread in Europe and the US. Whilst both diseases progress very differently, they are among the types of cancer which are most likely to be fatal in the Western world.

29 Aug 2018

Study shows that clinical diagnosis is not best predictor of avoidable hospitalization

The care of long-term nursing home patients can be fragmented by hospitalizations and re-hospitalizations, which are especially burdensome for frail older adults.

29 Aug 2018

Researchers identify neutrophil progenitor in the bone marrow of mice and humans

Neutrophils - short-lived, highly mobile and versatile - outnumber all other immune cells circulating through the blood stream.

29 Aug 2018

Scientists develop three-pronged model to predict ARDS in burn patients

For the first time, researchers have devised a model to predict burn patients who are most likely to develop life-threatening acute respiratory distress syndrome.

28 Aug 2018

Delivering miRNAs to treat patients with inflammatory bowel disease

Inflammatory bowel disease, such as Crohn disease and ulcerative colitis, are chronic inflammatory diseases of unknown cause, and the number of IBD patients is on the rise.

28 Aug 2018

Major bleeding associated with subsequent cancer diagnoses

Bleeding in patients treated with anticoagulants should stimulate a search for cancer, according to late breaking results from the COMPASS trial presented today at ESC Congress 2018.

28 Aug 2018

Stress gene increases vulnerability to developing chronic pain, study reveals

A study of more than 1,000 motor vehicle accident survivors published in JNeurosci reveals a common variant in a gene involved in the stress response that increases vulnerability to developing chronic pain. Addressing the interaction between this genetic variant and post-traumatic stress may represent a supplemental or alternative to treatment with addictive opioids.

28 Aug 2018

Low carbohydrate diet can increase risk of premature death, finds study

Low carbohydrate diets are unsafe and should be avoided, according to a large study presented today at ESC Congress 2018.

28 Aug 2018

Immune-related enzymes cause aggressive skin cancer in patients with Butterfly Syndrome

Patients with a rare skin disease, commonly called Butterfly Syndrome, that causes chronic blistering and extensive scarring also develop an aggressive and fatal form of cancer early in life.

28 Aug 2018

Researchers launch clinical trial to assess new drug combination against metastatic breast cancers

Researchers at University of California San Diego School of Medicine have launched a phase Ib clinical trial to assess the safety and tolerability of cirmtuzumab, in combination with standard chemotherapy, to treat metastatic or locally advanced breast cancer that cannot be surgically removed.

28 Aug 2018

Study reveals how gene variant affects chronic pain outcomes after trauma

The gene FKBP5 is a critical regulator of the stress response and affects how we respond to environmental stimuli. Previous studies have shown that certain variants of this gene play a role in the development of neuropsychiatric disorders such as posttraumatic stress disorder, depression, suicide risk, and aggressive behavior.

28 Aug 2018

Use of HIV RNA expression inhibitors restores immune function in HIV patients on cART

Immune activation and inflammation persist in the majority of treated HIV-infected individuals and is associated with excess risk of mortality and morbidity.

28 Aug 2018

New treatment can offer relief to people with chronic runny nose, postnasal drip and cough

A new treatment that delivers a freezing or near-freezing temperature to the back of the nose of patients can offer relief to people suffering from chronic stuffy or runny nose, postnasal drip and cough. These symptoms result from persistently inflamed nose and sinuses, a condition known as chronic rhinitis.

28 Aug 2018

Cedars-Sinai researchers develop simpler, more accurate method to estimate body fat

Cedars-Sinai investigators have developed a simpler and more accurate method of estimating body fat than the widely used body mass index, or BMI, with the goal of better understanding obesity.

27 Aug 2018

Antithrombin drug does not reduce risk of myocardial infarction, stroke in heart failure patients

The antithrombin drug rivaroxaban does not reduce the risk of a composite endpoint of survival, myocardial infarction and stroke after an episode of worsening heart failure in patients with heart failure, sinus rhythm, and coronary artery disease, according to late breaking results from the COMMANDER HF trial presented today in a Hot Line Session at ESC Congress 2018 and with simultaneous publication in NEJM.

27 Aug 2018

Care coordination has huge impact on better health of older adults with multiple chronic diseases

For older adults with multiple chronic diseases, such as diabetes, depression, heart disease and others, care coordination appears to have the biggest impact on better health, according to a study published in CMAJ.

27 Aug 2018

Chronic News and Research

Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes

New study supports motor cortex 'excitability' as cause of restless legs syndrome

Researchers receive $6 million NIH grant to improve treatment for Chagas disease

Hurricane Maria’s official death toll in Puerto Rico now stands at nearly 3,000

Researchers discover mechanism that steers growth of cancer cells in melanoma and liver cancer

Study shows that clinical diagnosis is not best predictor of avoidable hospitalization

Researchers identify neutrophil progenitor in the bone marrow of mice and humans

Scientists develop three-pronged model to predict ARDS in burn patients

Delivering miRNAs to treat patients with inflammatory bowel disease

Major bleeding associated with subsequent cancer diagnoses

Stress gene increases vulnerability to developing chronic pain, study reveals

Low carbohydrate diet can increase risk of premature death, finds study

Immune-related enzymes cause aggressive skin cancer in patients with Butterfly Syndrome

Researchers launch clinical trial to assess new drug combination against metastatic breast cancers

Study reveals how gene variant affects chronic pain outcomes after trauma

Use of HIV RNA expression inhibitors restores immune function in HIV patients on cART

New treatment can offer relief to people with chronic runny nose, postnasal drip and cough

Cedars-Sinai researchers develop simpler, more accurate method to estimate body fat

Antithrombin drug does not reduce risk of myocardial infarction, stroke in heart failure patients

Care coordination has huge impact on better health of older adults with multiple chronic diseases

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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