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SARS-CoV-2 ORF8 interferes with antibody-dependent cellular cytotoxicity

Researchers describe the effect of ORF8 and the immune-evasion activity used by SARS-CoV-2 to escape humoral responses.

5 Apr 2022

Gut bacterium may be an important factor in resistance to antihypertensive medications

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

5 Apr 2022

Combining two biomarkers could help identify patients with subcortical small-vessel disease

In recent years, subcortical small-vessel disease has become an increasingly common cognitive diagnosis.

5 Apr 2022

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

Critical Path Institute's Type 1 Diabetes Consortium (T1DC) today announced that the European Medicines Agency has issued a positive qualification opinion for pancreatic islet autoantibodies as enrichment biomarkers for type 1 diabetes (T1D) prevention trials.

5 Apr 2022

Patients treated with edoxaban after TAVR do not find reduction in mini strokes, blood clots in the brain

Patients treated with the blood thinner edoxaban for six months after a heart valve replacement procedure experienced fewer symptomless blood clots inside the heart valve replacement than patients who were treated with two antiplatelet drugs, according to data presented at the American College of Cardiology's 71st Annual Scientific Session.

5 Apr 2022

Study shows superiority of Chocolate Touch device for opening blocked arteries in the leg

Patients treated for a blocked artery in the leg were significantly more likely to have an open artery without further interventions at 12 months if they received the second-generation paclitaxel-coated balloon catheter known as the Chocolate Touch device compared with those receiving the commercially-available Lutonix drug-coated balloon catheter, according to a study presented at the American College of Cardiology's 71st Annual Scientific Session.

5 Apr 2022

Novel transcatheter repair system for tricuspid regurgitation shows promising results at one year

Patients with tricuspid regurgitation, a common and debilitating form of valvular heart disease, who received a novel investigational device intended to repair the defective valve experienced significant improvements in blood flow through the heart and in quality of life at one year, according to research presented at the American College of Cardiology's 71st Annual Scientific Session.

5 Apr 2022

Sodium thiosulfate shows no benefits for reducing heart damage following a heart attack

Sodium thiosulfate showed no benefits for reducing injury to damaged areas of heart muscle following a heart attack, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

5 Apr 2022

Implantable heart rhythm monitor does not benefit NSTEMI patients

Patients who received an implantable heart rhythm monitor after suffering a heart attack did not have fewer subsequent cardiovascular events overall, but a subset of patients whose heart attack was classified as non-ST segment elevation myocardial infarction (NSTEMI) did see strong benefits, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

5 Apr 2022

SARS-CoV-2 Omicron breakthrough infections induce antibodies with cross-variant neutralization potential and recall memory B cells

Researchers reported breakthrough infections by SARS-CoV-2’s new variant of concern, Omicron, that elicited broadly cross-reactive neutralizing antibodies in the BNT162b2-vaccinated individuals.

5 Apr 2022

Pre-existing memory B cell dynamics during SARS-CoV-2 Omicron breakthrough infection

A new study analyzed the recall of pre-existent cross-reactive memory B cells upon the SARS-CoV-2 Omicron breakthrough infections.

5 Apr 2022

Investigating extensive SARS-CoV-2 neutralizing immunoglobulins from COVID-19 recovered subjects

A new study discovered immunoglobulins with powerful broad-acting neutralizing capacity against SARS-CoV-2 from SARS-CoV-2 convalescents.

5 Apr 2022

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Blood News and Research

SARS-CoV-2 ORF8 interferes with antibody-dependent cellular cytotoxicity

Gut bacterium may be an important factor in resistance to antihypertensive medications

Combining two biomarkers could help identify patients with subcortical small-vessel disease

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

Patients treated with edoxaban after TAVR do not find reduction in mini strokes, blood clots in the brain

Study shows superiority of Chocolate Touch device for opening blocked arteries in the leg

Novel transcatheter repair system for tricuspid regurgitation shows promising results at one year

Sodium thiosulfate shows no benefits for reducing heart damage following a heart attack

Implantable heart rhythm monitor does not benefit NSTEMI patients

SARS-CoV-2 Omicron breakthrough infections induce antibodies with cross-variant neutralization potential and recall memory B cells

Pre-existing memory B cell dynamics during SARS-CoV-2 Omicron breakthrough infection

Investigating extensive SARS-CoV-2 neutralizing immunoglobulins from COVID-19 recovered subjects

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Explanatory AI system enables more accurate diagnosis of fetal congenital heart disease

Losing sleep over the pandemic? Work flexibility may be a boon for night owls’ health

Prior COVID vaccination induces a more robust antibody response to Omicron

Aggressively warming patients during surgery offers no benefit, study says

Study provides new insights into cause of metastasis in prostate cancer

Powerhouse-pruning protein may also help make energy rapidly available for growing new blood vessels

Higher cereal fiber intake associated with lower inflammation

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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