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Mutations may underlie how the most aggressive lymphomas arise and resist therapies

The key to understanding how the most aggressive lymphomas arise and resist current therapies may lie in mutations that disrupt a critical natural selection process among antibody-producing B cells, according to a multi-institutional preclinical study led by Weill Cornell Medicine investigators.

19 Jan 2023

Mpox has been silently circulating in non-mpox-endemic nations for 20 years, according to new study

Researchers described the evolution of the mpox virus (MPXV) before the 2022 outbreak.

19 Jan 2023

Comprehensive analysis of genome sequences unravels the elusive origins of bubonic plague

Seeking to better understand more about the origins and movement of bubonic plague, in ancient and contemporary times, researchers at McMaster University, University of Sydney and the University of Melbourne, have completed a painstaking granular examination of hundreds of modern and ancient genome sequences, creating the largest analysis of its kind.

19 Jan 2023

Researchers create large-scale 2D and 3D spatial maps of colorectal cancer

In the United States, turning 45 brings with it a rather unpleasant rite of passage: the beginning of regular colonoscopies, in which an endoscope equipped with a light and a camera is used to visually check the colon for signs of cancer.

19 Jan 2023

New research reveals that childhood omicron infections have been under-reported in Canadian schools

A recent study from the east coast of Canada evaluated the extent of under-reporting among school children from elementary to high schools.

19 Jan 2023

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Researchers explored how mutations in emergent SARS-CoV-2 variants affect viral function, human immunity, and recognition by therapeutic antibodies.

19 Jan 2023

Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

A new study describes that tight transmission bottlenecks restrict the evolution of SARS-CoV-2 in the transmission chain. SARS-CoV-2 is the causative pathogen of the COVID-19 pandemic.

18 Jan 2023

Poor hygiene practices in hospitals may lead to antibiotic resistance

A new paper in Evolution, Medicine, and Public Health, published by Oxford University Press, indicates that antibiotic resistance may result from poor hygiene practices in hospitals or other medical facilities.

17 Jan 2023

New research finds community interactions drive antibiotic tolerance in bacteria

In a new study, researchers examined the evolutionary trajectory of a lab-grown community of bacterium, Escherichia coli, having two interacting strains.

17 Jan 2023

Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2

Researchers evaluated the use of receptor decoys for SARS-CoV-2 based on soluble forms of ACE2 for immunological prophylaxis and management of COVID-19 through the use of AAV vectors.

16 Jan 2023

Researchers develop innovative STAb therapy for a type of leukemia

Researchers of the Hospital Universitario 12 de Octubre in Madrid and the Josep Carreras Leukaemia Research Institute have developed a cell therapy for a type of leukemia which currently has very few treatment options.

16 Jan 2023

Artemisia argyi plant extracts and phytochemicals shown to inhibit SARS-CoV-2 in new research

Researchers reported that Artemisia argyi extracts and phytochemicals could inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Jan 2023

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

Scientists from the Institut Pasteur, Université Paris Cité, the CNRS and the Collège de France have used paleogenomics to trace 10,000 years of human immune system evolution.

13 Jan 2023

Machine learning tools help unravel why human accelerated regions evolved so quickly

Humans and chimpanzees differ in only one percent of their DNA. Human accelerated regions (HARs) are parts of the genome with an unexpected amount of these differences.

13 Jan 2023

Researchers analyze the ancestry components in modern and historic VARV genomes

A recent study published in Microbial Genomics analyzed the molecular evolution of the variola virus (VARV)

13 Jan 2023

Recent findings on original antigenic sin and SARS-CoV-2

Researchers collated the findings of studies relating original antigenic sin with SARS-CoV-2 evolution.

13 Jan 2023

The 2022 U.S. RSV surge consisted of a variety of pre-existing viruses

In a recent study posted to the medRxiv* preprint server, researchers investigated whether the upsurge in respiratory syncytial virus (RSV) infections during the autumn season of 2022 occurred due to the emergence of a novel, highly transmissible RSV strain or whether multiple pre-existing RSV strains were responsible for the increase in RSV case counts during the period.

12 Jan 2023

Evolution News and Research

Mutations may underlie how the most aggressive lymphomas arise and resist therapies

Mpox has been silently circulating in non-mpox-endemic nations for 20 years, according to new study

Comprehensive analysis of genome sequences unravels the elusive origins of bubonic plague

Researchers create large-scale 2D and 3D spatial maps of colorectal cancer

New research reveals that childhood omicron infections have been under-reported in Canadian schools

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

Poor hygiene practices in hospitals may lead to antibiotic resistance

New research finds community interactions drive antibiotic tolerance in bacteria

Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2

Researchers develop innovative STAb therapy for a type of leukemia

Artemisia argyi plant extracts and phytochemicals shown to inhibit SARS-CoV-2 in new research

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

Machine learning tools help unravel why human accelerated regions evolved so quickly

Researchers analyze the ancestry components in modern and historic VARV genomes

Recent findings on original antigenic sin and SARS-CoV-2

The 2022 U.S. RSV surge consisted of a variety of pre-existing viruses

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

Unique mass spectrometry-based approach to study specific changes in DNA after replication

How might healthcare transform in the next 50 years?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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