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Levels of anti-Mullerian hormone may help predict bone loss during menopause transition

Physicians may be able to determine if menopause-related bone loss is already in progress or about to begin by measuring the level of a hormone that declines as women approach their final menstrual period, new UCLA research finds.

4 Apr 2022

ECG can pinpoint hospitalized COVID-19 patients at high risk of mortality

A simple electrocardiogram (ECG) can pinpoint hospitalized COVID-19 patients at high risk of death who might need intensive management. That's the finding of a study presented at EHRA 2022, a scientific congress of the European Society of Cardiology.

4 Apr 2022

Researchers use breast milk to identify new set of protein biomarkers for cancer

A simple blood test for women of all ages and risk levels could one day be possible thanks to a new set of protein biomarkers that researchers identified using breast milk.

4 Apr 2022

Genetic risk score predicts the likelihood of cardiovascular events in people with Type 2 diabetes

A risk score based on a gene map predicted the likelihood of high blood pressure leading to heart problems or stroke in people with Type 2 diabetes, according to a study published today in the American Heart Association's peer-reviewed journal Hypertension.

4 Apr 2022

Magnitude and durability of SARS-CoV-2 S-binding antibody titers in the pre-variant era among healthcare workers in NYC

Researchers analyzed sera samples of 400 participants of the PARIS study to evaluate the risk of SARS-CoV-2 infection and seroreversion for an average of 84 days.

4 Apr 2022

New type of anti-clotting drug reduces bleeding incidents among patients with atrial fibrillation

A new type of anti-clotting drug caused fewer bleeding incidents among patients with atrial fibrillation than the commonly prescribed apixaban, according to results from a head-to-head comparison of the two.

4 Apr 2022

Study suggests severe neuroinvasion by SARS-CoV-2 in individuals with alcohol use disorder

Researchers investigated the effect of repeated alcohol exposure and withdrawal on angiotensin-converting enzyme 2 and transmembrane serine protease 2 expression, putative regulators of SARS-CoV-2 entry, in discrete brain regions.

4 Apr 2022

Patients’ perilous months-long waiting for Medicaid coverage is a sign of what’s to come

Korra Elliott has tried to avoid seeing a doctor while waiting to get on Medicaid. She worries she can't afford more bills without any insurance coverage. But in early March — five months, she said, after applying and with still no decision about her application — a suspected case of the flu sent her blood pressure soaring and landed her in the emergency room.

4 Apr 2022

Case study of multi-system inflammatory syndrome in children in a fully vaccinated teenager

A new preprint describes the importance of recognizing this complication, reporting a case of MIS-C without a prior history of this infection.

4 Apr 2022

Study identifies new risk factors for recovery after reconstructive breast surgery

Factors such as anemia and anticoagulants have more impact on hospitalization time after breast reconstruction than "common" risk factors.

4 Apr 2022

Addition of alirocumab to high-intensity statin treatment reduces key measures of plaque vulnerability

Compared with a placebo, the addition of the injectable cholesterol-lowering drug alirocumab to high-intensity statin treatment in patients who have had a heart attack resulted in twofold greater reductions in three key measures of plaque vulnerability that signal risk for future cardiac events, according to research presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Experimental siRNA therapeutic shows promise to reduce an important driver of heart disease risk

While there are effective therapies to reduce the risk of heart disease by lowering low-density lipoprotein (LDL), or "bad" cholesterol, and other lipids, to date there are no approved treatments to lower lipoprotein(a), a lesser-known driver of heart disease risk.

3 Apr 2022

Customized digital alert improves guideline-directed medical therapy for heart failure

Physicians prescribed significantly more guideline-directed medications for heart failure if they received a customized digital alert via an electronic health record (EHR) system when inputting medical orders shortly after seeing a patient, according to a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Patiromer lowers hyperkalemia risk in heart failure patients taking RAASi therapy

Patients taking renin-angiotensin-aldosterone system inhibitor (RAASi) medications for heart failure had significantly lower blood potassium levels when taking patiromer—a drug that helps to prevent the body from absorbing too much potassium—compared with a placebo, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Extension study shows mavacamten’s efficacy and safety in treating hypertrophic cardiomyopathy

Use of mavacamten, a novel cardiac myosin inhibitor, to treat people with symptomatic obstructive hypertrophic cardiomyopathy (HCM), a condition that results in excess thickening of the heart muscle, resulted in continued benefits in patient quality of life and outcomes over an extended period of time, according to interim data from the EXPLORER-HCM extension study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Leakage after left atrial appendage occlusion associated with higher risk of adverse events

Patients who had leakage to the left atrial appendage due to incomplete device sealing after left atrial appendage occlusion (LAAO) experienced more clotting and bleeding events within a year following their procedure compared with patients who had no leaking, according to a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Smartwatch application can be used for atrial fibrillation screening

Atrial fibrillation (AFib) was confirmed in nearly 94% of people who were initially identified to have signs of the heart rhythm disorder by a smartwatch application and who followed up with a clinician, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

New drug shows promise in relieving symptoms associated with hypertrophic cardiomyopathy

A new drug shows promise in providing relief to cardiomyopathy patients experiencing shortness of breath, according to late-breaking research presented today at the American College of Cardiology (ACC) Scientific Session in Washington, D.C.

3 Apr 2022

TLR7 and MARK1 genomic variants impact COVID-19 prognosis

Researchers conduct a massive exome-wide genome study to explore the connections between gene variants/deleterious mutations and COVID-19 outcomes.

3 Apr 2022

Global study demonstrates some benefits of flu vaccine in people with heart failure

People with heart failure who received an annual flu shot had lower rates of pneumonia and hospitalization on a year-round basis and a reduction in major cardiovascular events during peak flu season, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Blood News and Research

Levels of anti-Mullerian hormone may help predict bone loss during menopause transition

ECG can pinpoint hospitalized COVID-19 patients at high risk of mortality

Researchers use breast milk to identify new set of protein biomarkers for cancer

Genetic risk score predicts the likelihood of cardiovascular events in people with Type 2 diabetes

Magnitude and durability of SARS-CoV-2 S-binding antibody titers in the pre-variant era among healthcare workers in NYC

New type of anti-clotting drug reduces bleeding incidents among patients with atrial fibrillation

Study suggests severe neuroinvasion by SARS-CoV-2 in individuals with alcohol use disorder

Patients’ perilous months-long waiting for Medicaid coverage is a sign of what’s to come

Case study of multi-system inflammatory syndrome in children in a fully vaccinated teenager

Study identifies new risk factors for recovery after reconstructive breast surgery

Addition of alirocumab to high-intensity statin treatment reduces key measures of plaque vulnerability

Experimental siRNA therapeutic shows promise to reduce an important driver of heart disease risk

Customized digital alert improves guideline-directed medical therapy for heart failure

Patiromer lowers hyperkalemia risk in heart failure patients taking RAASi therapy

Extension study shows mavacamten’s efficacy and safety in treating hypertrophic cardiomyopathy

Leakage after left atrial appendage occlusion associated with higher risk of adverse events

Smartwatch application can be used for atrial fibrillation screening

New drug shows promise in relieving symptoms associated with hypertrophic cardiomyopathy

TLR7 and MARK1 genomic variants impact COVID-19 prognosis

Global study demonstrates some benefits of flu vaccine in people with heart failure

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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