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Protein produced by soft-tissue sarcomas makes immune cells ‘go bad’

Investigators from Cedars-Sinai Cancer have discovered that cancerous tumors called soft-tissue sarcomas produce a protein that switches immune cells from tumor-attacking to tumor-promoting.

21 Jun 2022

New screening tool could increase the number of tests on solid tumor sample by up to 50 times

A screening tool developed at the University of Strathclyde, UK, could increase the number of tests on a solid tumor sample by up to 50 times.

21 Jun 2022

Wistar scientists discover a new way to boost a person's immune response to tumors

Due to the development of resistance to chemotherapy and recurring tumors, patients with ovarian cancer often have low survival rates.

21 Jun 2022

TB-causing bacteria can evolve rapidly in response to new environments, study says

Researchers have identified how the bacterium that causes tuberculosis (TB) can evolve rapidly in response to new environments, says a study published today in eLife.

21 Jun 2022

A class of protein-cleaving enzymes suspected to play a role in hereditary brain disease

Similar to Alzheimer's disease, the hereditary disease spinocerebellar ataxia type 17 (SCA17) leads to the destruction of brain nerve cells and the premature death of patients.

21 Jun 2022

Researchers compare the development and persistence of antibody and T-cell responses elicited by the mRNA BNT162b2 vaccine or SARS-CoV-2 infection

Researchers comparatively assessed the generation of B lymphocyte-mediated antibody responses and T lymphocyte-mediated cellular responses between mRNA BNT162b vaccinees and mild COVID-19 patients.

21 Jun 2022

SARS-CoV-2 infection may be a trigger of myelin oligodendrocyte glycoprotein-associated disorder

A new study reported four cases of Myelin Oligodendrocyte Glycoprotein-Associated Disorder that commenced after SARS-CoV-2 infection.

21 Jun 2022

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

Researchers evaluated the efficacy of PHELA, a traditional African drug, against SARS-CoV-2 in vitro.

21 Jun 2022

Researchers identify the role of TREM2-positive macrophages in non-alcoholic fatty liver disease

A MedUni Vienna study team has identified the role of a specific subtype of macrophages (white blood cells) in progressive non-alcoholic fatty liver disease.

21 Jun 2022

Clonal diversity impacts longevity of T cell reaction specific to SARS-CoV-2 epitope

A recent article under review at the Nature Portfolio journal and currently available on the Research Square* preprint server analyzed the factors influencing the durability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epitope-specific T cell reaction.

21 Jun 2022

Increased docosahexaenoic acid intake may lower risk for Alzheimer’s and dementia

An increase in the concentration of DHA in RBCs is associated with a reduced risk of Alzheimer's disease and all-cause dementia

21 Jun 2022

How specific comorbidities impact severity of COVID-19

Researchers identify the association between severe COVID-19 and specific comorbidities.

20 Jun 2022

Study uncovers novel treatment for chromophobe renal cell carcinoma

Chromophobe renal cell carcinoma (ChRCC) is a rare form of kidney cancer for which there are currently no proven treatments for metastatic or unresectable disease.

20 Jun 2022

UTSW study provides a potential avenue for the development of new antivirals against influenza

A collaborative study from UT Southwestern scientists has identified a new function for a protein called TAO2 that appears to be key to inhibiting replication of the influenza virus, which sickens millions of individuals worldwide each year and kills hundreds of thousands.

20 Jun 2022

Study offers new insight into the growth of blood vessels

Blood vessels must adapt their growth to the nutrients available in their surroundings so that they can keep organs adequately supplied. A team led by Michael Potente has identified two proteins that are important for this process and published their findings in Nature Metabolism.

20 Jun 2022

New model rapidly scans the genome of cancer cells and identifies mutations that drive tumor growth

Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.

20 Jun 2022

Proteins in liquor could provide information about inflammatory processes in the brain

Alzheimer's, Parkinson's and other neurodegenerative diseases are associated with inflammatory processes in the brain.

20 Jun 2022

Area-level education and income linked with patients' lung cancer stage at the time of diagnosis

Lung cancer is the leading cause of cancer-related deaths in the United States, and early detection and treatment are key to prolonging survival in patients.

20 Jun 2022

Researchers highlight the impact of macrophage subtypes on acute kidney injury to CKD transition

Acute kidney injury (AKI) is a condition in which kidneys are unable to filter waste from the blood effectively, leading to various health complications.

20 Jun 2022

New combination of drugs effective against T-cell acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most common cancer affecting children. The T-ALL form of leukemia that emerges from early T lineage cells has a poorer prognosis than B-lineage ALL. The prognosis for relapsed T-ALL is very poor and new therapies are sorely needed.

20 Jun 2022

Cell News and Research

Protein produced by soft-tissue sarcomas makes immune cells ‘go bad’

New screening tool could increase the number of tests on solid tumor sample by up to 50 times

Wistar scientists discover a new way to boost a person's immune response to tumors

TB-causing bacteria can evolve rapidly in response to new environments, study says

A class of protein-cleaving enzymes suspected to play a role in hereditary brain disease

Researchers compare the development and persistence of antibody and T-cell responses elicited by the mRNA BNT162b2 vaccine or SARS-CoV-2 infection

SARS-CoV-2 infection may be a trigger of myelin oligodendrocyte glycoprotein-associated disorder

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

Researchers identify the role of TREM2-positive macrophages in non-alcoholic fatty liver disease

Clonal diversity impacts longevity of T cell reaction specific to SARS-CoV-2 epitope

Increased docosahexaenoic acid intake may lower risk for Alzheimer’s and dementia

How specific comorbidities impact severity of COVID-19

Study uncovers novel treatment for chromophobe renal cell carcinoma

UTSW study provides a potential avenue for the development of new antivirals against influenza

Study offers new insight into the growth of blood vessels

New model rapidly scans the genome of cancer cells and identifies mutations that drive tumor growth

Proteins in liquor could provide information about inflammatory processes in the brain

Area-level education and income linked with patients' lung cancer stage at the time of diagnosis

Researchers highlight the impact of macrophage subtypes on acute kidney injury to CKD transition

New combination of drugs effective against T-cell acute lymphoblastic leukemia

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