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Older melanoma patients fare better on immune checkpoint blockade therapy

Patient age correlates with response to immunotherapy in melanoma and depleting regulatory T cells in young patients may have a therapeutic potential to enhance response in younger patients, according to research from The Wistar Institute. Study results were published online in Clinical Cancer Research.

13 Jun 2018

Medicare takes aim at boomerang hospitalizations of nursing home patients

"Oh my God, we dropped her!" Sandra Snipes said she heard the nursing home aides yell as she fell to the floor. She landed on her right side where her hip had recently been replaced.

13 Jun 2018

Researchers shed light on how stem cells move

Researchers have made important discoveries about how stem cells move, interact with each other and respond to their environment.

13 Jun 2018

Special issue focuses on how endocrine-disrupting chemicals influence behavior

Rutgers School of Public Health Professor Dr. Emily Barrett, PhD, and North Carolina State University Professor Dr. Heather Patisaul, PhD, have guest edited a special issue of the journal Hormones and Behavior.

13 Jun 2018

Novel approach induces cell death via dual targeting of DNA repair mechanism

Proteins commonly known as BRCA - short for BReast CAncer susceptibility gene- serve a critical role in cellular DNA repair, but when mutated they allow genetic errors to replicate, facilitating cancer development.

13 Jun 2018

Researchers discover unique process of brain cell death in MS

Researchers at the University of Alberta have discovered a unique process of brain cell death that affects the cells that are most vulnerable in multiple sclerosis.

13 Jun 2018

Scientists develop artificial intelligence platform to diagnose many diseases

A platform that can diagnose several diseases with a high degree of precision using metabolic markers found in patients' blood has been developed by scientists at the University of Campinas in Brazil

13 Jun 2018

Scientists explain 'Hangry'

There have been many instances when we have been irritable, annoyed, negative, and grumpy only because underneath we are feeling hungry. A new term “hangry” has been coined to explain this condition. Researchers have delved into why this occurs in a latest study.

13 Jun 2018

UNC study provides insight into mechanism of CHD4-related heart defects

Heart defects are the most common type of birth defect, and can be caused by mutations in the gene CHD4. Researchers at the UNC School of Medicine have now revealed key molecular details of how CHD4 mutations lead to heart defects.

12 Jun 2018

Scientists discover protective mechanism against atherosclerosis

Atherosclerosis, the pathological narrowing of blood vessels, is the underlying cause for the majority of strokes and heart attacks, the major causes of mortality worldwide according to the WHO.

12 Jun 2018

AbCellera and Denali collaborate to discover new antibodies to fight neurodegenerative diseases

AbCellera Biologics Inc. today announced the successful completion of the first phase of its collaboration with Denali Therapeutics Inc.

12 Jun 2018

Tiny optical sensors open door to developing wearable device for medical diagnosis

Scientists from The Australian National University have designed tiny optical sensors that open the door to developing a wearable device that allows doctors to medically diagnose people’s health in real time.

12 Jun 2018

Hydrogel releases nerve-protecting agent to restore breathing in animal models

One of the most severe outcomes of spinal cord injury from car accidents, sports impacts, or other neck trauma, is losing the ability to control breathing, with patients often requiring artificial ventilation for the rest of their lives.

12 Jun 2018

Scientists pinpoint potential treatment target for pediatric liver cancer

A protein in the cell nucleus already targeted therapeutically for several types of cancer has now been linked to an aggressive form of pediatric liver cancer called hepatoblastoma (HBL), according to a study published in the Nature journal Communications Biology.

11 Jun 2018

Research aims to better understand psychological mechanisms of hunger-induced emotional states

What makes someone go from simply being hungry to full-on "hangry"? More than just a simple drop in blood sugar, this combination of hunger and anger may be a complicated emotional response involving an interplay of biology, personality and environmental cues, according to research published by the American Psychological Association.

11 Jun 2018

CRISPR-Cas9 technique may raise cancer risk

Therapeutic use of gene editing with the so-called CRISPR-Cas9 technique may inadvertently increase the risk of cancer, according to a new study from Karolinska Institutet, Sweden, and the University of Helsinki, Finland, published in Nature Medicine.

11 Jun 2018

Deep-frozen juices defrosted to room temperature can increase carotenoids level in body

Researchers from the Laboratory of Food Color and Quality at the University of Seville have published a study in which it is shown how certain types of cold treatment that are used by the citrus fruits industry in the preparation of juices have a great impact on the color of orange juice and on the concentration and bioaccessibility of the carotenoids present in the juice.

11 Jun 2018

Eating honey can reduce serious injuries in children who swallowed button battery, shows study

A team of ear, nose, and throat specialists has demonstrated that eating honey after swallowing a button battery has the potential to reduce serious injuries in small children.

11 Jun 2018

Researchers isolate bacteria that pose triple threat from a patient in the U.S.

Researchers from the Emory Antibiotic Resistance Center describe the first strain of carbapenem-resistant, hypermucoviscous Klebsiella pneumoniae exhibiting colistin heteroresistance and enhanced virulence isolated from a patient in the United States.

11 Jun 2018

Novel computer models for individualization of HIV therapy in countries with limited healthcare resources

New predictive computer models designed to optimize HIV therapy in countries with limited healthcare resources are published online this week in the Journal of Antimicrobial Chemotherapy.

11 Jun 2018