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Middle ear infection can lead to deadly neurological complications

While antibiotics have greatly reduced the dangers of ear infections, serious neurological complications, including hearing loss, facial paralysis, meningitis and brain abscess still occur, according to an article in the journal Current Neurology and Neuroscience Reports.

16 Apr 2018

Researchers generate stable cartilage tissue from adult mesenchymal stem cells

Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.

16 Apr 2018

Anti-PD-1 treatment reduces tumor size and post-surgical relapse of lung cancer

A drug given to early stage lung cancer patients before they undergo surgery showed major tumor responses in the removed tumor and an increase in anti-tumor T-cells that remained after the tumor was removed, which resulted in fewer relapse cases in the patients.

16 Apr 2018

CNIO researchers determine structure of protein complex related to cell survival

A team from the Spanish National Cancer Research Centre has determined for the first time the high-resolution structure of a complex (R2TP) involved in key processes for cell survival and in diseases such as cancer.

16 Apr 2018

Finding ways to reverse obesity’s lingering, pro-cancer effects

Like exposure to too much sun and drinking alcohol, obesity is a risk factor for cancer. Researchers at the University of North Carolina Lineberger Comprehensive Cancer Center are working to be a part of the solution -- they want to find ways to reverse obesity-linked biological changes in the body that are associated with cancer growth.

16 Apr 2018

Expedeon relocates to Cambridge as part of integration into SYGNIS Group

SYGNIS AG today announced the completion of the relocation of its subsidiary company, Expedeon, into the Company’s existing facilities in Cambridge, UK.

16 Apr 2018

Sleep deprivation increases brain protein linked to Alzheimer's disease

Losing just one night of sleep led to an immediate increase in beta-amyloid, a protein in the brain associated with Alzheimer's disease, according to a small, new study by researchers at the National Institutes of Health. In Alzheimer's disease, beta-amyloid proteins clump together to form amyloid plaques, a hallmark of the disease.

13 Apr 2018

Temperature has marked effect on toxicity of insecticides used for malaria control

Ambient temperature has a marked effect on the toxicity of the most commonly used insecticides for malaria control, according to a study led by ISGlobal, an institution supported by the "la Caixa" Foundation.

13 Apr 2018

Study reveals prevalence of substance use and suicide among U.S. adolescents

Examining more than 20 years of national data for U.S. adolescents, a research team led by Andrew Subica at the University of California, Riverside reports that adolescents have high prevalence of alcohol, cigarette, and marijuana use, and concerning rates of suicide-related thoughts and behaviors.

13 Apr 2018

Glucose metabolism is key to neural network development, finds study

A new study has found that glucose metabolism is critical for the development of neural networks in the brain.

13 Apr 2018

Medical device coated with new bacteria resistant materials approved for use by hospitals

A medical device coated with new bacteria resistant materials, discovered by a team at the University of Nottingham, has been approved for use by hospitals in the UK and Europe.

13 Apr 2018

Deep learning enhances smartphone microscopes into laboratory-grade equipments

Researchers at the UCLA Samueli School of Engineering have demonstrated that deep learning, a powerful form of artificial intelligence, can discern and enhance microscopic details in photos taken by smartphones. The technique improves the resolution and color details of smartphone images so much that they approach the quality of images from laboratory-grade microscopes.

13 Apr 2018

Research reveals immune suppressive role of soluble antibodies in tumor progression

Wistar researchers have found that soluble antibodies promote tumor progression by inducing accumulation of myeloid-derived suppressor cells (MDSCs) in pre-clinical cancer models. Results were published online in Cancer Immunology Research.

13 Apr 2018

KU Cancer Center to present evidence supporting anti-cancer drug at AACR 2018

The University of Kansas Cancer Center will present preclinical evidence supporting Ciclopirox Prodrug (CPX-POM), an anti-cancer agent currently in Phase I clinical trials, at the American Association for Cancer Research 2018 Annual Meeting in Chicago. Ciclopirox Prodrug was discovered by researchers at The University of Kansas Cancer Center and KU's Institute for Advancing Medical Innovation.

12 Apr 2018

New, sensitive HBV assay may allow earlier detection of hepatocellular carcinoma

Chronic hepatitis B virus (HBV) can progress to cirrhosis and hepatocellular carcinoma (HCC). A study published in The Journal of Molecular Diagnostics describes a new HBV assay that offers advantages over currently used methods because it has the capability to detect closed circular DNA (cccDNA) in serum, single cells, and preserved tissue samples.

12 Apr 2018

CU Anschutz scientists receive $3.8 million DoD grant to boost EB research

Scientists from the Gates Center for Regenerative Medicine at the University of Colorado School of Medicine are part of a consortium awarded $3.8 million from the U.S. Department of Defense to move discoveries in stem cell-created skin grafts into the manufacturing stage, bringing further hope to victims of debilitating inherited skin diseases.

12 Apr 2018