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BWH bioengineers develop flare-responsive hydrogel to treat arthritis

Arthritis flares - the unpredictable and often sudden worsening of arthritis symptoms -- can be debilitating. These episodes can make the management of inflammatory arthritis, which includes rheumatoid arthritis and psoriatic arthritis, challenging for patients and physicians.

3 Apr 2018

Researchers discover how muscles regulate oxygen consumption

A new study by researchers from Karolinska Institutet shows that an enzyme called FIH determines how muscles consume oxygen. Without the enzyme, the need for oxygen increases during physical exercise. The finding is of potential significance to elite athletes, who have been found to have higher levels of FIH in their muscles than others.

3 Apr 2018

Study highlights disconnection between patient satisfaction scores and online physician reviews

Physicians who receive negative reviews online do not receive similar responses in rigorous patient satisfaction surveys, according to new Mayo Clinic research in Mayo Clinic Proceedings. Yet, compared with colleagues without negative reviews, they score lower on factors that go beyond patient interactions and are beyond their immediate control.

3 Apr 2018

Genetic testing could help guide blood-thinner treatment after stent placement

Using genetic testing to inform which blood thinner to use following a procedure to open narrowed blood vessels resulted in significantly fewer complications among patients, according to new research in Circulation: Genomic and Precision Medicine, an American Heart Association journal.

3 Apr 2018

Stable proteins in the brain offer clues to long-term memory and learning in mice

In the tiny brain space where two nerve cells meet, chemical and electric signals shuttle back and forth, a messaging system that ebbs and flows in those synaptic spaces, sometimes in ways that scientists believe aid and abet learning and memory.

3 Apr 2018

Gut bacteria may hold clues to predict effectiveness of cancer immunotherapies

The composition of bacteria in the gastrointestinal tract may hold clues to help predict which cancer patients are most apt to benefit from the personalized cellular therapies that have shown unprecedented promise in the fight against hard-to-treat cancers, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

3 Apr 2018

Researchers fabricate injectable bandage to promote wound healing

A penetrating injury from shrapnel is a serious obstacle in overcoming battlefield wounds that can ultimately lead to death.Given the high mortality rates due to hemorrhaging, there is an unmet need to quickly self-administer materials that prevent fatality due to excessive blood loss.

3 Apr 2018

Researchers identify 200 mutations in non-coding DNA that play role in cancer

Most of the human genome - 98 percent - is made up of DNA but doesn't actually encode genes, the recipes cells use to build proteins.

2 Apr 2018

Scientists identify new function for colon cancer gene

Colon cancer is the second most common cause of cancer-related deaths. The APC protein has long been known for its critical role in preventing colorectal cancer. When APC is inactivated, the development of colorectal cancer is triggered.

2 Apr 2018

Researchers develop new non-invasive test for early detection of urothelial cancer

Urothelial cancers of the bladder and upper urinary tract are among the most common cancers encountered worldwide. In the United States, urothelial cancers are among the most costly cancers to treat.

31 Mar 2018

Porex to display innovations in laboratory liquid handling, diagnostics and chromatography at Analytica 2018

At next month’s Analytica event, Porex Corporation will display new solutions for laboratory and medical professionals that improve accuracy and purity in liquid handling, speed fluid transfer of diagnostics and optimize chromatography operations.

From Porex Corporation 31 Mar 2018

New research on gait assessment using Shimmer3 IMUs

The way that people walk is generally a good indicator of their musculoskeletal health, and poor or uncoordinated mobility can result in falls and even injury. Gait research is frequently used as an indication of changes in a person’s mobility which could potentially lead to falls.

From Shimmer 31 Mar 2018

Adult-onset degenerative disease mechanism begins much earlier than previously thought

The disease mechanism for adult-onset progressive degenerative diseases begins much earlier than previously thought, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

30 Mar 2018

Alfred Blalock’s medical breakthroughs have been saving many lives

The year was 1925, and Alfred Blalock was already a failure at age 26. The born-and-raised Georgian earned a bachelor's degree from the University of Georgia in 1918, then a medical doctorate from Johns Hopkins University four years later. But he didn't get the surgical residency he coveted at Hopkins; he ended up interning in urology instead.

29 Mar 2018

Researchers create synthesized nanosheets to inactivate or detect pathogens

Researchers have developed a process for creating ultrathin, self-assembling sheets of synthetic materials that can function like designer flypaper in selectively binding with viruses, bacteria, and other pathogens.

29 Mar 2018

Tiny biochip holds promise for rapid and accurate disease detection

A novel invention by a team of researchers from the National University of Singapore (NUS) holds promise for a faster and cheaper way to diagnose diseases with high accuracy.

29 Mar 2018

New $3.2 million grant funds research to advance promising malaria vaccine

The Global Health Innovative Technology Fund has awarded the University of Florida and partners in the United States and Japan $3.2 million to advance a promising vaccine to prevent transmission of malaria.

29 Mar 2018

Researchers find expression of lymphatic markers in proliferative diabetic retinopathy tissues

Proliferative diabetic retinopathy is a major sight-threatening diabetic complication. Nearly all patients with type I diabetes and over 60% of patients with type II diabetes develop retinopathy after 20 years of diabetes, despite metabolic control.

29 Mar 2018

New tracing methods reveal breadth of neural communication in visual cortex

An international collaboration of neuroscientists have today published a paper in Nature demonstrating the breadth of neural communication in visual cortex using a combination of methods for tracing the projections of individual neurons across the brain.

29 Mar 2018