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The potential role of the gut microbiome in modifying patient responses to statin therapy

Researchers discovered strong links between human gut microbiome makeup and statin on- and off-target effects, probably beneficial in medication tailoring.

13 May 2022

Study shows how co-transplanting islet cells with SA-FasL-microgels reverses diabetic symptoms

Islet cell transplants are a promising treatment that can cure difficult-to-treat type 1 diabetes. The cells, taken from a donor pancreas, provide patients with a sustainable and tightly controlled source of insulin.

13 May 2022

New mouse model shows the connection between stress, depression and cardiovascular disease risk

Results from a new mouse model may aid in understanding how depression and prolonged and severe stress increase the risk of cardiovascular disease, according to preliminary research presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2022.

13 May 2022

Researchers use bacteriophages to treat antibiotic-resistant mycobacterial lung infection

For the first time, researchers have successfully used bacteriophages – viruses that kill bacteria – to treat an antibiotic-resistant mycobacterial lung infection, clearing the way for a young National Jewish Health patient with cystic fibrosis to receive a life-saving lung transplant.

13 May 2022

Surprising discovery opens new avenues for in vitro organ culture

How do our cells organize themselves to give their final shape to our organs? The answer lies in morphogenesis, the set of mechanisms that regulate their distribution in space during embryonic development.

13 May 2022

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Researchers generated a recombinant influenza virus expressing micro ribonucleic acid (miRNAs) expressed in cardiomyocytes to infect mice, which served as a model to study the etiology of influenza-associated cardiac pathology.

13 May 2022

Microbes can influence which of the gut's genes are being called into action

The microbes that help break down food actually tell the gut how to do its job better, according to a new study in mice at Duke.

13 May 2022

Antibiotics disrupt the immune system in the gut leading to fungal infection

Patients prescribed antibiotics in hospital are more likely to get fungal infections because of disruption to the immune system in the gut, according to a new study from the University of Birmingham and National Institutes of Health.

13 May 2022

Chronic obstructive pulmonary disease leads to premature senescence of the immune system

A study conducted at the University of São Paulo's Medical School (FM-USP) in Brazil, with results reported in an article published in the journal Immunity & Ageing, shows that chronic obstructive pulmonary disease (COPD) leads to premature senescence (age-related impairment) of the immune system.

13 May 2022

Collectively moving malaria parasites form vortices that are largely determined by physical principles

The disease of malaria is triggered by single-celled parasites that accumulate in large groups in the salivary glands of mosquitoes before transmission to human beings.

13 May 2022

Adolescent and young adult leukemia survivors have reduced long-term survival compared to peers without cancer

Researchers at The University of Texas MD Anderson Cancer Center have discovered that adolescent and young adult (AYA) cancer survivors of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) have reduced long-term survival rates compared to their peers without cancer.

13 May 2022

Study explores macromolecular viral entry inhibitors as broad-spectrum first-line antivirals with anti-SARS-CoV-2 activities

Researchers created polystyrene sulfonate with significantly different molar masses, constructed these polymers as an exterior around spherical gold nanoparticles of various sizes to improve multivalency effects, measured antiviral effects of the antivirals on numerous viruses in vitro, and investigated the method of interaction of the leads with SARS-CoV-2 and lentiviral particles.

13 May 2022

Analysis reveals increasing prevalence of esophageal cancer and Barrett’s esophagus in middle-aged adults

Adults aged 45 to 64 experienced a nearly doubled rate of esophageal cancer and a 50 percent increase in the precancerous condition Barrett's esophagus between 2012 and 2019, according to a database analysis of roughly five million patients to be presented at Digestive Disease Week 2022.

13 May 2022

Researchers reveal mechanism for spread of antibiotic resistance among bacteria

A bacteria calledStaphylococcusaureusis widespread and generally harmless, but can cause infections known as "opportunistic infections".

13 May 2022

Researchers discover new gene that confers resistance to prostate cancer treatment

Northwestern Medicine investigators have identified a gene that confers resistance to a common prostate cancer treatment, according to a study published in Cancer Research.

13 May 2022

Exploring short-term effectiveness of COVID-19 booster vaccine and stable CD8+ T cell memory after three doses

A new study has longitudinally traced and profiled the CD8+ T cell responses after COVID-19 mRNA booster vaccination.

13 May 2022

Saving lives with living cells: Beckman Coulter Life Sciences launches AQUIOS STEM System to provide a new solution for stem cell analysis

Creating the industry’s first stem cell analysis update in nearly 25 years, Beckman Coulter Life Sciences – a global leader in laboratory automation and innovation – launches an evolution of the gold standard in hematopoietic stem cell enumeration, the AQUIOS STEM System.

13 May 2022

Development of a novel surface plasmon resonance-based assay to determine kinetics of SARS-CoV-2 spike – human ACE2 interaction

A team of scientists has recently studied the kinetic and thermodynamic characteristics of interaction between human ACE2 and spike receptor-binding domains of different variants of SARS-CoV-2.

13 May 2022

SARS-CoV-2 N-terminal domain modulates S1/S2 cleavage and spike-mediated functions

In a recent study posted to the bioRxiv* preprint server, researchers explored the role of the N-terminal domain (NTD) of the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) spike (S) protein in SARS-CoV-2 fusion with the host membranes and coronavirus disease 2019 (COVID-19).

12 May 2022

Topical drugs may regress congenital giant nevi and prevent skin cancer

About one in 20,000 infants is born with what's called a congenital giant nevus - a huge, pigmented mole that may cover much of the face and body.

12 May 2022

Cell News and Research

The potential role of the gut microbiome in modifying patient responses to statin therapy

Study shows how co-transplanting islet cells with SA-FasL-microgels reverses diabetic symptoms

New mouse model shows the connection between stress, depression and cardiovascular disease risk

Researchers use bacteriophages to treat antibiotic-resistant mycobacterial lung infection

Surprising discovery opens new avenues for in vitro organ culture

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Microbes can influence which of the gut's genes are being called into action

Antibiotics disrupt the immune system in the gut leading to fungal infection

Chronic obstructive pulmonary disease leads to premature senescence of the immune system

Collectively moving malaria parasites form vortices that are largely determined by physical principles

Adolescent and young adult leukemia survivors have reduced long-term survival compared to peers without cancer

Study explores macromolecular viral entry inhibitors as broad-spectrum first-line antivirals with anti-SARS-CoV-2 activities

Analysis reveals increasing prevalence of esophageal cancer and Barrett’s esophagus in middle-aged adults

Researchers reveal mechanism for spread of antibiotic resistance among bacteria

Researchers discover new gene that confers resistance to prostate cancer treatment

Exploring short-term effectiveness of COVID-19 booster vaccine and stable CD8+ T cell memory after three doses

Saving lives with living cells: Beckman Coulter Life Sciences launches AQUIOS STEM System to provide a new solution for stem cell analysis

Development of a novel surface plasmon resonance-based assay to determine kinetics of SARS-CoV-2 spike – human ACE2 interaction

SARS-CoV-2 N-terminal domain modulates S1/S2 cleavage and spike-mediated functions

Topical drugs may regress congenital giant nevi and prevent skin cancer

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