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Study investigates what causes blood malignancies linked to gene therapy for sickle cell disease

Gene therapy trials for sickle cell disease have been showing great promise, even offering hope of a cure. But in early 2021, the trials ground to a halt after reports of blood malignancies in two people in a trial sponsored by bluebird bio.

16 Feb 2022

Twin study identifies the influence of environment and genetics in multiple sclerosis

Researchers at the University of Zurich and Munich's LMU Klinikum hospital have studied the immune system of pairs of monozygotic twins to identify the influence of the environment and of genetics in cases of multiple sclerosis.

16 Feb 2022

Omicron breakthrough boosts neutralization titers a little more than a 3rd COVID vaccine dose

Researchers compare the neutralizing antibody titers in individuals who received two or three mRNA vaccine doses and experienced breakthrough infections.

16 Feb 2022

Gut enzymes open a gateway to create universal blood-type donor organs

A study published in Science Translational Medicine performed at the Latner Thoracic Surgery Research Laboratories and UHN's Ajmera Transplant Centre has proved that it is possible to convert blood type safely in donor organs intended for transplantation.

16 Feb 2022

Heart attack survivors may have a lower risk of Parkinson's disease

People who have had a heart attack may be slightly less likely than people in the general population to develop Parkinson's disease later in life, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

16 Feb 2022

Study shows the true prevalence of statin intolerance worldwide is between 6 to 10%

As many as one in two patients stop taking statins, reduce the dose or take them irregularly because they believe the cholesterol-lowering drugs cause muscle pain and other side-effects.

16 Feb 2022

Antibodies become more powerful for at least six months after COVID-19 vaccination

For at least six months after COVID-19 vaccination, antibodies produced by immune cells become steadily more formidable and more precisely targeted against the virus that causes COVID-19, according to a study of the antibody response to the Pfizer-BioNTech vaccine by researchers at Washington University School of Medicine in St. Louis.

16 Feb 2022

Pioneering treatment for stroke due to intracerebral hemorrhage

For decades, University of Cincinnati researchers have been pioneers in the field of stroke research.

16 Feb 2022

New cholera vaccine generates long-lasting antibody responses in mice

Cholera, a diarrheal disease caused by the highly transmissible bacteria Vibrio cholerae, kills tens of thousands of people each year worldwide.

16 Feb 2022

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

A new study discusses the state of current knowledge about the potential use of tea polyphenols in the prevention and treatment of COVID-19.

16 Feb 2022

Pregnancy outcomes of pregnant women infected by SARS-CoV-2

A new study evaluated the pregnancy outcomes of pregnant women in the third trimester who were infected by SARS-CoV-2 for the detection of the virus in the placenta and different samples of the newborn as well as detection of antibodies in the cord blood.

16 Feb 2022

Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

Researchers investigated the role of platelets in the adverse immune response against a COVID-19 vaccine.

16 Feb 2022

Human nose organoids provide better understanding of the first steps toward SARS-CoV-2 infection

Preclinical models that recapitulate aspects of human airway disease are essential for the advancement of novel therapeutics and vaccines.

16 Feb 2022

The long-term consequences of SARS-CoV-2 infection in people with HIV

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from the United States (US) analyzed a cohort of patients with human immunodeficiency virus (HIV) (PWH) recovering from coronavirus disease 2019 (COVID-19) and characterized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific immune responses in these patients.

15 Feb 2022

Stem cell infusion improves the survival of mice with sepsis

A one-time infusion of stem cells from bone marrow improves the survival of mice with sepsis, shows a study published today in eLife.

15 Feb 2022

Study uncovers most critical genes that cause coronary heart disease

The most critical genes that cause coronary heart disease and trigger heart attacks have been identified in a major new study.

15 Feb 2022

New tool appears to accurately identify patients at risk of death from alcohol-associated hepatitis

Mayo Clinic researchers have developed a new scoring system to help health care professionals predict the 30-day mortality risk for patients with alcohol-associated hepatitis, and the tool appears to more accurately identify patients at highest risk of death and those likely to survive.

15 Feb 2022

Blood News and Research

Study investigates what causes blood malignancies linked to gene therapy for sickle cell disease

Twin study identifies the influence of environment and genetics in multiple sclerosis

Omicron breakthrough boosts neutralization titers a little more than a 3rd COVID vaccine dose

Gut enzymes open a gateway to create universal blood-type donor organs

Heart attack survivors may have a lower risk of Parkinson's disease

Study shows the true prevalence of statin intolerance worldwide is between 6 to 10%

Antibodies become more powerful for at least six months after COVID-19 vaccination

Pioneering treatment for stroke due to intracerebral hemorrhage

New cholera vaccine generates long-lasting antibody responses in mice

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

Pregnancy outcomes of pregnant women infected by SARS-CoV-2

Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

Human nose organoids provide better understanding of the first steps toward SARS-CoV-2 infection

The long-term consequences of SARS-CoV-2 infection in people with HIV

Stem cell infusion improves the survival of mice with sepsis

Study uncovers most critical genes that cause coronary heart disease

New tool appears to accurately identify patients at risk of death from alcohol-associated hepatitis

Neutralizing antibody levels to different SARS-CoV-2 epitopes fluctuate over time

Cardiac MRI shows a similar injury pattern for vaccine-associated myocarditis

Researchers create a comprehensive atlas of cerebrovascular cell types

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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