Laboratory News and Research

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Higher susceptibility of some babies to Zika virus has a genetic origin, study shows

Microcephaly, brain calcification, skeletal alterations, auditory and visual deficits - these are examples of the damage that can be caused by Zika virus in babies born to mothers infected during pregnancy.

2 Feb 2018

Geneva researchers highlight new way to control tumor progression

For a tumor to grow, it must develop blood vessels that supply nutrients and oxygen. Preventing tumor vascularization is therefore an interesting anti-tumor therapy that has been explored over the last ten years.

2 Feb 2018

$Researchers develop novel method to aid fracture recovery$

Researchers develop novel method to aid fracture recovery

Researchers from Michigan Medicine have developed a novel method to aid the repair of difficult-to-heal fractures.

2 Feb 2018

New modular platform offers robust biological approach that targets endless number of diseases

The biological complexity of cancer and other diseases demands a more formidable arsenal of therapies than currently available. Most therapeutic approaches ignore the dynamic molecular network of genes, targeting instead only very few selected disease-related genes.

1 Feb 2018

Two bacterial species collaborate to drive development of colon cancers

Patients with an inherited form of colon cancer harbor two bacterial species that collaborate to encourage development of the disease, and the same species have been found in people who develop a sporadic form of colon cancer, a study led by a Johns Hopkins Bloomberg~Kimmel Institute for Cancer Immunotherapy research team finds.

1 Feb 2018

Historic study involving Simmons Cancer Center shows effectiveness of CAR-T therapy

A historic study involving researchers from UT Southwestern's Harold C. Simmons Comprehensive Cancer Center demonstrates the effectiveness of CAR-T therapy, which uses genetically modified immune cells to treat acute lymphoblastic leukemia (ALL) in children and young adults. The research appears in the New England Journal of Medicine.

1 Feb 2018

Harvard scientists identify molecular machinery responsible for dopamine release in the brain

Studied for decades for its critical role in movement control and reward-seeking behaviors, the neurotransmitter dopamine has been the focus of numerous efforts to understand its activity, particularly when it goes awry in disorders such as Parkinson's and addiction.

1 Feb 2018

Scientists decipher molecular structure of antipsychotic docked in its key receptor

Antipsychotic drugs - which transformed mental health care following their chance discovery in the mid-20th Century - may finally be poised for a long-overdue makeover incorporating structure-based design.

1 Feb 2018

Scientists discover the genetic cause of immune disorders

Scientists from the Cincinnati Children’s have successfully identified a gene mutation that affects T cell function and promotes immune disorders.

1 Feb 2018

Viruses closely related to Zika may cause fetal brain damage and death, study finds

Two viruses closely related to Zika – West Nile and Powassan – can spread from an infected pregnant mouse to her fetuses, causing brain damage and fetal death, according to a new study from Washington University School of Medicine in St. Louis.

31 Jan 2018

Scientists discover role of two specific HOX genes in colon cancer development

In breakthrough colon cancer research, scientists at Christiana Care Health System's Center for Translational Cancer Research of the Helen F. Graham Cancer Center & Research Institute have discovered that over-expression of HOXA4 and HOXA9 genes in colon cancer stem cells promotes cell replication and contributes to the overpopulation of stem cells that drives colon cancer development.

31 Jan 2018

Fentanyl may put users at risk of amnesia, WVU report reveals

A case report by a West Virginia University neuropsychologist suggests a new reason fentanyl- alone, or in combination with stimulants- may put substance users at risk, whether they take it knowingly or not. It may cause amnesia.

31 Jan 2018

Study finds close connection between eye and cardiovascular damage in type 1 diabetes

In people with type 1 diabetes, high levels of blood glucose eventually can harm blood vessels in the eye, kidney, heart and other organs--but the damage may be inflicted by different biological mechanisms in different organs.

31 Jan 2018

Researchers explore new biomarkers for early detection of Parkinson’s from speech

The study of new non-invasive biomarkers able to identify the Parkinson's disease from the speech of patients is the joint work carried out by researchers from Universidad Politécnica de Madrid, Massachusetts Institute of Technology and Johns Hopkins University.

31 Jan 2018

Researchers advance understanding of abnormal mineral accumulation in arteries

A team of researchers from McGill University has advanced the scientific understanding of abnormal mineral accumulation in arteries, a complication often seen in patients with chronic kidney disease and diabetes. Mineralized arteries may affect heart functions, leading to death in some instances.

31 Jan 2018

Laboratory News and Research

Higher susceptibility of some babies to Zika virus has a genetic origin, study shows

Geneva researchers highlight new way to control tumor progression

Researchers develop novel method to aid fracture recovery

New modular platform offers robust biological approach that targets endless number of diseases

Two bacterial species collaborate to drive development of colon cancers

Historic study involving Simmons Cancer Center shows effectiveness of CAR-T therapy

Harvard scientists identify molecular machinery responsible for dopamine release in the brain

Scientists decipher molecular structure of antipsychotic docked in its key receptor

Scientists discover the genetic cause of immune disorders

Viruses closely related to Zika may cause fetal brain damage and death, study finds

Scientists discover role of two specific HOX genes in colon cancer development

Fentanyl may put users at risk of amnesia, WVU report reveals

Study finds close connection between eye and cardiovascular damage in type 1 diabetes

Researchers explore new biomarkers for early detection of Parkinson’s from speech

Researchers advance understanding of abnormal mineral accumulation in arteries

New organ-on-a-chip technology provides simple setting to study blood vessel formation

Stealth gene shuttles open up new avenues to treat aggressive cancers

New guide helps researchers to choose the right micropipette

Inhaled carbon dioxide triggers group of neurons responsible for arousal

Study paves new way for development of vaccines against epidemics

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Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics