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New study on mutation origination fundamentally challenges neo-Darwinism

A new study by a team of researchers from Israel and Ghana has brought the first evidence of nonrandom mutation in human genes, challenging a core assumption at the heart of evolutionary theory by showing a long-term directional mutational response to environmental pressure.

31 Jan 2022

New approach to make RNA vaccines easier to swallow

Like most vaccines, RNA vaccines have to be injected, which can be an obstacle for people who fear needles. Now, a team of MIT researchers has developed a way to deliver RNA in a capsule that can be swallowed, which they hope could help make people more receptive to them.

31 Jan 2022

Combined strategy suppresses the growth of deadly brain tumor

Short bursts of radiation therapy dramatically enhanced the efficiency of targeting glioblastomas with natural nanoparticle-based immunotherapy, thus suppressing growth of the deadly tumor, inducing anti-tumor immunity and prolonging survival in animal models, a research team at Massachusetts General Hospital has discovered.

31 Jan 2022

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

A University of South Florida Health preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

31 Jan 2022

Researchers identify genetic cause of rare interstitial lung disease in a young child

New research from Washington University School of Medicine in St. Louis has solved the medical mystery of why a 2-year-old child — seemingly healthy at birth — succumbed to an undiagnosed, rare illness.

31 Jan 2022

Yellow fever vaccine-vectored YF-S0 as a potent COVID-19 vaccine candidate

In a new study, a team of researchers developed YF-S0, an exceptionally potent COVID-19 vaccine candidate using live-attenuated yellow fever vaccine YF17D as a vector.

31 Jan 2022

Study reveals potential mechanism for iron accumulation in the aging brain

Breakdowns in regulatory mechanisms cause iron to build up in the brain as organisms grow older, increasing oxidative stress and causing cellular damage, according to a Northwestern Medicine study published in the journal eLife.

31 Jan 2022

Researchers create model to predict COVID-19 mortality

In a new study, researchers have created a model that can help determine the outcome of COVID-19 infection in patients in the ICU.

31 Jan 2022

Nucleocapsid antigen found to be a sensitive biomarker for acute COVID-19 infection

In a new study, researchers found that nucleocapsid antigen in the blood (antigenemia) is a sensitive and specific biomarker for acute coronavirus disease 2019 infection.

31 Jan 2022

Patients undergoing neurosurgical operations with concomitant COVID-19 infection have higher rates of perioperative complications

This unique paper compares neurosurgical patients with COVID-19 for perioperative complications to those without COVID-19.

31 Jan 2022

Vaccine-induced immunological memory is similar for Omicron and Delta SARS-CoV-2 variants

A new study by Norwegian researchers suggests that vaccine-induced immunological memory and the activation of recall responses in the body yields similar coverage for Omicron and Delta variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The paper is currently available on the medRxiv* preprint server while it undergoes peer review.

31 Jan 2022

Research shows minks mimic severe COVID-19 symptoms, including ARDS

Minks may be a suitable animal model for testing severe COVID-19 infections, finds a recent bioRxiv* preprint study. While mice and ferrets are used in preclinical severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is currently no model specific to severe disease.

30 Jan 2022

Immunity based upon “mild" Omicron infection is weak for Omicron reinfection

Researchers evaluate antibody responses in vaccinated individuals who subsequently developed Delta and Omicron SARS-CoV-2 breakthrough infections.

30 Jan 2022

COVID-19 vaccines elicit cross-reactive antibodies against endemic coronaviruses

Researchers study the interaction between immunity to endemic coronaviruses and SARS-CoV-2.

30 Jan 2022

Adults and children have similar neutralizing antibody responses to SARS-CoV-2 infection

Researchers describe the kinetics of SARS-CoV-2-specific serum antibodies in convalescent children over six months following infection.

30 Jan 2022

New app and lab kit transform a smartphone into COVID-19 / flu detection system

In a potential game changer for COVID-19 pandemic control efforts, a new cell phone app and lab kit have transformed a smartphone into a COVID-19 / flu detection system.

29 Jan 2022

Weekly alcohol intake of less than 14 units still increases the risk of cardiovascular events

Drinking less than the UK's recommended limit of 14 units of alcohol per week still increases the risk of cardiovascular issues such as heart and cerebrovascular disease, according to new research published in the journal Clinical Nutrition.

29 Jan 2022

Study reveals role of a protein in healthy functioning of blood stem cells

A protein that masterminds the way DNA is wrapped within chromosomes has a major role in the healthy functioning of blood stem cells, which produce all blood cells in the body, according to a new study from researchers at Weill Cornell Medicine.

28 Jan 2022

Hospitalized COVID-19 patients more likely to experience heavy bleeding when prescribed full-dose blood thinners

Patients with COVID-19 in the intensive care unit (ICU) prescribed full-dose blood thinners are significantly more likely to experience heavy bleeding than patients prescribed a smaller yet equally effective dose, according to a recent University at Buffalo-led study.

28 Jan 2022

Blood tests may enable simpler, more accurate early diagnosis of ALS

Blood tests may enable more accurate diagnosis of ALS at an earlier stage of the disease. As described in a study by researchers at University of Gothenburg and Umeå University, it involves measuring the blood level of a substance that, as they have also shown, varies in concentration depending on which variant of ALS the patient has.

28 Jan 2022

Blood News and Research

New study on mutation origination fundamentally challenges neo-Darwinism

New approach to make RNA vaccines easier to swallow

Combined strategy suppresses the growth of deadly brain tumor

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

Researchers identify genetic cause of rare interstitial lung disease in a young child

Yellow fever vaccine-vectored YF-S0 as a potent COVID-19 vaccine candidate

Study reveals potential mechanism for iron accumulation in the aging brain

Researchers create model to predict COVID-19 mortality

Nucleocapsid antigen found to be a sensitive biomarker for acute COVID-19 infection

Patients undergoing neurosurgical operations with concomitant COVID-19 infection have higher rates of perioperative complications

Vaccine-induced immunological memory is similar for Omicron and Delta SARS-CoV-2 variants

Research shows minks mimic severe COVID-19 symptoms, including ARDS

Immunity based upon “mild" Omicron infection is weak for Omicron reinfection

COVID-19 vaccines elicit cross-reactive antibodies against endemic coronaviruses

Adults and children have similar neutralizing antibody responses to SARS-CoV-2 infection

New app and lab kit transform a smartphone into COVID-19 / flu detection system

Weekly alcohol intake of less than 14 units still increases the risk of cardiovascular events

Study reveals role of a protein in healthy functioning of blood stem cells

Hospitalized COVID-19 patients more likely to experience heavy bleeding when prescribed full-dose blood thinners

Blood tests may enable simpler, more accurate early diagnosis of ALS

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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