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Low-cost test could open new avenues for earlier diagnosis, treatment of rare genetic disorders

A newly developed test to screen for three rare genetic disorders simultaneously in newborns was feasible, reliable and scalable, according to a new study.

24 Jan 2022

Neurological complications of the SARS-CoV-2 vaccine

In a study published in the latest issue of the journal Neurological Sciences, a team of researchers described a three-patient case series presenting with neurological manifestations after the coronavirus disease 2019 (COVID-19) vaccination, followed by a literature review, to propose hypotheses on how neurological symptoms might develop after vaccination.

24 Jan 2022

Review highlights sex differences in ischemic stroke occurrence among young adults

Women ages 35 years and younger were 44% more likely to have an ischemic stroke (caused by blocked blood vessels in the brain) than their male counterparts, according to a new review of more than a dozen international studies on sex differences in stroke occurrence, published today in a Go Red for Women 2022 spotlight issue of Stroke, a peer-reviewed journal of the American Stroke Association, a division of the American Heart Association.

24 Jan 2022

WashU part of major study aimed at identifying causes, effects of schizophrenia in young people

Washington University School of Medicine in St. Louis is part of a major international study aimed at identifying causes and effects of the early stages of schizophrenia in young people, with the goal of improving early diagnosis and treatment.

24 Jan 2022

Blood proteins could be potential targets for future drugs to slow aging process

Two blood proteins have been shown by scientists to influence how long and healthy a life we live, research suggests.

24 Jan 2022

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)."

24 Jan 2022

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

In a new study, researchers evaluated the single-cell transcriptomes from bronchiolar lavage in three adult cohorts comprising of obese and non-obese SARS-CoV-2 patients.

24 Jan 2022

Novel gene therapy for diseased muscle fiber repair

In this interview, News-Medical speaks to Dr. Jyoti K. Jaiswal about his latest research into gene therapies for limb-girdle muscular dystrophy 2B.

24 Jan 2022

Exploring loss of Y chromosome in white blood cells as a risk-factor of life-threatening COVID-19 in men

Researchers published a study exploring the possibilities of predisposing men for a life-threatening disease course of COVID-19.

24 Jan 2022

Antibody response 18 months after SARS-CoV-2 infection in vaccinated and unvaccinated individuals

A new study assessed the dynamics of IgG titers over 18 months in patients who had recovered from COVID-19 infections during March 2020.

24 Jan 2022

Computer simulations help better understand the impact of pregnancy on kidneys

Researchers are using computer simulations to better understand the impacts pregnancy can have on kidneys.

24 Jan 2022

Highly anxious men may be at greater risk for developing heart disease and type 2 diabetes

Middle-aged men who are anxious and worry more may be at greater biological risk for developing heart disease, stroke and type 2 diabetes, also called cardiometabolic disease, as they get older, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.

24 Jan 2022

Human endogenous retrovirus type W envelope protein found to be a biomarker of COVID-19 severity

A new study revealed that the expression of HERV-W envelope protein (ENV) in lymphoid cells from COVID-19 patients correlated with disease outcome making them biomarkers of lymphocyte exhaustion.

24 Jan 2022

Alpaca-derived antibody fragment disrupts interaction between SARS-CoV-2 spike protein and human ACE2

Researchers have been investigating the potential for using nanobodies – special immune particles from llamas and alpacas – against the disease.

24 Jan 2022

Vaccine wars ignite in California as lawmakers seek stronger laws

California is poised to become the front line of America's vaccination wars. State lawmakers are drafting the toughest covid-19 vaccine legislation in the country, backed by a new pro-vaccine lobbying force promising to counter anti-vaccine activists who have threatened government officials and shut down public meetings across the state.

24 Jan 2022

The doctor didn’t show up, but the hospital ER still charged $1,012

Dhaval Bhatt had been warned about hospital emergency rooms. "People always told me to avoid the ER in America unless you are really dying," said Bhatt, an immigrant from India who got a Ph.D. in pharmacology in the U.S. and is now a research scientist at Washington University in St. Louis.

24 Jan 2022

Study finds stable T-Cell response against Omicron after mRNA booster vaccination

A new study measured T cell activity in vaccinated individuals and found a third vaccine provided substantial T-cell immunity against the Omicron variant of SARS-CoV-2.

24 Jan 2022

Patients and providers have different expectations about access to medical records, study finds

While both patients and clinicians prioritize information transparency, a 21st Century Cures Act requirement for the immediate release of test and lab results is proving more controversial, according to recently published survey results of clinicians and patients.

24 Jan 2022

Gene replacement therapy could help mend a broken heart, study suggests

How can you mend a broken heart? According to researchers from Japan, in some cases gene replacement therapy just might do the trick.

24 Jan 2022

Researchers find ELF5 gene a leading candidate behind severe COVID-19

Are there any risk factors that predispose patients to severe COVID-19 outcomes? A recent study published in the medRxiv* preprint server sheds light on this popular question. Using a combination of population genetics to single-cell RNA sequencing, European researchers identified the respiratory epithelial cell-specific ELF5 gene as a potential mediator for severe COVID-19 cases.

24 Jan 2022

Blood News and Research

Low-cost test could open new avenues for earlier diagnosis, treatment of rare genetic disorders

Neurological complications of the SARS-CoV-2 vaccine

Review highlights sex differences in ischemic stroke occurrence among young adults

WashU part of major study aimed at identifying causes, effects of schizophrenia in young people

Blood proteins could be potential targets for future drugs to slow aging process

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

Novel gene therapy for diseased muscle fiber repair

Exploring loss of Y chromosome in white blood cells as a risk-factor of life-threatening COVID-19 in men

Antibody response 18 months after SARS-CoV-2 infection in vaccinated and unvaccinated individuals

Computer simulations help better understand the impact of pregnancy on kidneys

Highly anxious men may be at greater risk for developing heart disease and type 2 diabetes

Human endogenous retrovirus type W envelope protein found to be a biomarker of COVID-19 severity

Alpaca-derived antibody fragment disrupts interaction between SARS-CoV-2 spike protein and human ACE2

Vaccine wars ignite in California as lawmakers seek stronger laws

The doctor didn’t show up, but the hospital ER still charged $1,012

Study finds stable T-Cell response against Omicron after mRNA booster vaccination

Patients and providers have different expectations about access to medical records, study finds

Gene replacement therapy could help mend a broken heart, study suggests

Researchers find ELF5 gene a leading candidate behind severe COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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