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Insight into the future of genetic testing

In this interview, we speak to Sheetal Parmar, vice president of medical affairs and head of clinical services at Natera, about their cell-free DNA (cfDNA) testing services.

From Natera 15 Apr 2022

Effects of COVID-19 treatment best with combination therapy

There is a steadily growing arsenal of drugs for COVID-19. Researchers from Charité – Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität (FU) Berlin have studied the mechanisms of action of antiviral and anti-inflammatory drugs.

15 Apr 2022

Cell’s production of lipids can be a key factor in determining cell fate

How does a cell "decide" what type of cell to become? The question of "cell fate" has been explored for decades now, especially in the context of stem cell biology, but there are still gaps in our understanding.

15 Apr 2022

Inhibiting key signaling pathway in immune cells may slow down Alzheimer's disease

Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer's and some other neurodegenerative diseases, suggests a study by Weill Cornell Medicine investigators.

14 Apr 2022

Yale research demonstrates the cancer relevance of known human genes

Following an analysis of over 12,000 human genes, research from Yale Cancer Center indicates there is cancer-relevant importance in a much larger proportion of human genes than current cancer research models suggest.

14 Apr 2022

Scientists discover differences in interaction of T-cells within tumor microenvironments

A team led by Northwestern Medicine investigators has discovered differences in the distribution and interaction of T-cells within the microenvironment of different regions of both brain tumors and brain metastases, according to findings published in the journal JCI Insight.

14 Apr 2022

New data-driven mechanistic approach can help reduce drug costs and treat diseases

A new data-driven mechanistic approach that predicts cell types within tissue will help to reduce drug costs and treat diseases that were difficult to develop drugs for, according to a West Virginia University scientist.

14 Apr 2022

Exploring strategies for successful delivery of messenger RNA therapeutics

Researchers reviewed the material properties and administration routes that could successfully deliver a messenger ribonucleic acid therapeutic agent to its targeted site.

14 Apr 2022

Recent advances in non-viral nano-vector delivery of CRISPR/Cas9 genome editing payloads

Researchers reviewed non-viral nano-vectors used for delivering the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-mediated genome editing system.

14 Apr 2022

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

In a recent study, researchers assessed the anti-COVID-19 efficacy of Salvia miltiorrhiza Bunge.

14 Apr 2022

Study reveals natural infection of pangolins with human RSV

A new study aimed to determine whether humans were able to transmit RSV to Malayan pangolins.

13 Apr 2022

COVID-19 may affect a group of biochemical reactions called one-carbon metabolism

A new study addresses the relationship between SARS-CoV-2 to the metabolism of one-carbon molecules in the host, suggesting new therapeutic pathways.

13 Apr 2022

Dietary influences on long COVID in children

A new study discusses possible mechanisms of long COVID in children and how they might relate to their dietary intake of important vitamins and elements.

13 Apr 2022

Structural differences between SARS-CoV-1 and SARS-CoV-2 RBDs

A new study compares the SARS-CoV-2 RBD to the SARS-CoV RBD using computational methods to understand their binding affinities to ACE2.

13 Apr 2022

Novel transdermal vaccine delivery for COVID-19 and cancer

Researchers assess the efficacy of a fluorocarbon modified chitosan system for the development of SARS-CoV-2 vaccines and tumor immunotherapy.

13 Apr 2022

People with COVID-19 can shed viral RNA in their feces months after initial infection

The extended presence of viral RNA in feces, but not respiratory samples, along with the association of fecal viral RNA shedding with GI symptoms suggest that SARS-CoV-2 infects the GI tract, and that this infection can be prolonged in a subset of individuals with COVID-19.

13 Apr 2022

Social connections predict the brain structure of primates

What's the link between social life and brain structure? Researchers from the University of Pennsylvania, the Stem Cell and Brain Research Institute at Inserm, and elsewhere are now one step closer to understanding this connection for rhesus macaques.

13 Apr 2022

Mayo Clinic researchers devise a combination approach to more effectively target solid tumors

Researchers at Mayo Clinic's Center for Individualized Medicine have devised an immunotherapy technique that combines chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, with a cancer-killing virus to more effectively target and treat solid cancer tumors.

13 Apr 2022

UCL researchers boost the effectiveness of therapeutic vaccine for chronic HBV

Scientists at UCL have significantly boosted the effectiveness of a therapeutic vaccine designed to control chronic hepatitis B (HBV) infection, after uncovering and thwarting 'the enemy within'.

13 Apr 2022

A kind of kiss between cells plays key role in the fight between immune system and blood cancer cells

Researchers at The Ottawa Hospital and the University of Ottawa have discovered that a kind of kiss between cells, called trogocytosis, plays a key role in the battle between the immune system and blood cancer cells.

13 Apr 2022

Cell News and Research

Insight into the future of genetic testing

Effects of COVID-19 treatment best with combination therapy

Cell’s production of lipids can be a key factor in determining cell fate

Inhibiting key signaling pathway in immune cells may slow down Alzheimer's disease

Yale research demonstrates the cancer relevance of known human genes

Scientists discover differences in interaction of T-cells within tumor microenvironments

New data-driven mechanistic approach can help reduce drug costs and treat diseases

Exploring strategies for successful delivery of messenger RNA therapeutics

Recent advances in non-viral nano-vector delivery of CRISPR/Cas9 genome editing payloads

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

Study reveals natural infection of pangolins with human RSV

COVID-19 may affect a group of biochemical reactions called one-carbon metabolism

Dietary influences on long COVID in children

Structural differences between SARS-CoV-1 and SARS-CoV-2 RBDs

Novel transdermal vaccine delivery for COVID-19 and cancer

People with COVID-19 can shed viral RNA in their feces months after initial infection

Social connections predict the brain structure of primates

Mayo Clinic researchers devise a combination approach to more effectively target solid tumors

UCL researchers boost the effectiveness of therapeutic vaccine for chronic HBV

A kind of kiss between cells plays key role in the fight between immune system and blood cancer cells

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