Neurosurgery News and Research

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Study provides more insights into abusive head injury in small children

Abusive head injury, sometimes referred to as shaken baby syndrome or non-accidental trauma, is the third leading cause of head injuries in small children in the US. For children under the age of 1 year, it is the cause of the majority of serious head injuries.

12 Jul 2016

UCLA researchers develop new combination therapy to activate immune response against glioblastoma

UCLA researchers have developed a new breakthrough combination treatment that utilizes a vaccine to activate an immune response against advanced brain tumors.

8 Jul 2016

Clinical trial to test low-dose heparin treatment for patients with ruptured brain aneurysm

A Louisville patient is the first to be enrolled in a national clinical trial to test a new treatment for patients who have suffered a ruptured brain aneurysm.

7 Jul 2016

Rapid number naming test can detect cognitively impaired people with AD

For the first time, researchers have determined that a brief, simple number naming test can differentiate between cognitively healthy elderly individuals and cognitively impaired people with Alzheimer's disease (AD), including those with mild cognitive impairment (MCI), as well as those with AD dementia.

6 Jul 2016

ADAPT technique offers promising outcomes for stroke patients with large-vessel clots

In an article published online April 16, 2016 by the Journal of Neurointerventional Surgery, investigators at the Medical University of South Carolina report promising 90-day outcomes for stroke patients with large-vessel clots who underwent thrombectomy or clot removal using the direct-aspiration, first pass technique.

30 Jun 2016

Researcher receives federal grant to advance study of tumor nanoimmunology

The five-year grant was awarded by the National Cancer Institute of the National Institutes of Health. The funds come on top of four previous grants to support Ljubimova's work. In all, the institute has awarded Ljubimova $16.5 million over the last five years.

29 Jun 2016

High levels of zinc may lead to kidney stone formation

David Killilea, PhD, a staff scientist at Children's Hospital Oakland Research Institute- the research arm of UCSF Benioff Children's Hospital Oakland - co-authored a study into the causes of kidney stones.

28 Jun 2016

Researchers seek to develop novel antibody to treat glioblastoma

Scientists of Helmholtz Zentrum München and the Munich University Hospital are developing a novel antibody to treat brain tumors.

22 Jun 2016

Pipeline Embolization Device safe, effective for treatment of complex brain aneurysms

A recently introduced technology called the Pipeline Embolization Device (PED) can provide a less-invasive approach for difficult-to-treat aneurysms of the arteries supplying blood to the front of the brain, reports a study in the July issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

22 Jun 2016

Simple model can help predict complication risks after surgery for CSM

A simple model consisting of four risk factors can help surgeons to predict the risk of complications after surgery for cervical spondylotic myelopathy (CSM)—a common condition causing compression of the spinal cord in the neck, reports a study in the July issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

22 Jun 2016

Caribbean, African-born women more likely to be admitted at ICU during delivery

Women born in the Caribbean or Africa are two times more likely to be admitted to an intensive care unit at the time of their delivery than Canadian-born women, a new study has found.

17 Jun 2016

Stroke can cause long-term damage to blood-spinal cord barrier, study finds

A team of researchers at the University of South Florida investigating the short and long-term effects of ischemic stroke in a rodent model has found that stroke can cause long-term damage to the blood-spinal cord barrier (BSCB), creating a "toxic environment" in the spinal cord that might leave stroke survivors susceptible to motor dysfunction and disease pathology.

14 Jun 2016

Johns Hopkins researchers develop lab test that accurately predicts glioblastoma aggression and spread

Johns Hopkins Medicine researchers report they have developed an experimental laboratory test that accurately clocks the “speed” of human brain tumor cell movement along a small glass “track.”

13 Jun 2016

Standard and intensive blood pressure treatments equally effective in controlling acute intracerebral hemorrhage

An international stroke study found that standard and intensive blood pressure treatments were equally effective in the emergency treatment of acute intracerebral hemorrhage, a type of stroke caused by bleeding into the brain.

9 Jun 2016

Barley products lower levels of two types of bad cholesterol linked to cardiovascular risk

Eating barley or foods containing barley significantly reduced levels of two types of "bad cholesterol" associated with cardiovascular risk, a St. Michael's Hospital research paper has found.

8 Jun 2016

Human stem cells restore motor function in chronic stroke patients

Injecting modified, human, adult stem cells directly into the brains of chronic stroke patients proved not only safe but effective in restoring motor function, according to the findings of a small clinical trial led by Stanford University School of Medicine investigators.

7 Jun 2016

Advances in precision diagnostics aid accurate detection of CNS tumors

Thanks to new methods of precision diagnostics, such as DNA sequencing and epigenetic analyses, it is becoming increasingly possible to identify specific central nervous system (CNS) tumors accurately and to provide targeted treatment. The Comprehensive Cancer Center of MedUni Vienna and Vienna General Hospital is one of the top centers in the world for diagnosing and treating this type of tumor.

6 Jun 2016

Retroviral replicating vector can extend lives of brain cancer patients

Doctors at UCLA, Cleveland Clinic, University of California San Diego School of Medicine and additional institutions have achieved a milestone in the development of a treatment for people with recurrent glioblastoma, the most common and aggressive form of brain cancer, by successfully demonstrating a modified virus that can extend the lives of patients with the disease.

2 Jun 2016

Multiple cell and gene therapies can enhance cardiac function in mice modeled with MI

Researchers at the University of Utah compared the therapeutic potential of umbilical cord-derived sub-epithelial cells (UC-SECs), bone marrow-derived mesenchymal stem cells (BM-MSCs) and induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) -- all derived from human tissue -- along with genes (S100a1 and SDF-1a) and growth factor (VEGF165) to evaluate how injected biologics might enhance cardiac function in mice modeled with myocardial infarction (MI; commonly referred to as heart attack).

2 Jun 2016

$CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory$

CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory

A two-year, multi-center clinical study with 167 patients with class III-IV refractory angina randomized to low and high dose CD34+ cells or placebo has revealed that patients who received either a high or low dose of CD34 -- a member of a family of proteins that have an impact on vascular-associated tissue -- cells had a significant reduction in angina frequency over patients who received placebo.

2 Jun 2016

Neurosurgery News and Research

Study provides more insights into abusive head injury in small children

UCLA researchers develop new combination therapy to activate immune response against glioblastoma

Clinical trial to test low-dose heparin treatment for patients with ruptured brain aneurysm

Rapid number naming test can detect cognitively impaired people with AD

ADAPT technique offers promising outcomes for stroke patients with large-vessel clots

Researcher receives federal grant to advance study of tumor nanoimmunology

High levels of zinc may lead to kidney stone formation

Researchers seek to develop novel antibody to treat glioblastoma

Pipeline Embolization Device safe, effective for treatment of complex brain aneurysms

Simple model can help predict complication risks after surgery for CSM

Caribbean, African-born women more likely to be admitted at ICU during delivery

Stroke can cause long-term damage to blood-spinal cord barrier, study finds

Johns Hopkins researchers develop lab test that accurately predicts glioblastoma aggression and spread

Standard and intensive blood pressure treatments equally effective in controlling acute intracerebral hemorrhage

Barley products lower levels of two types of bad cholesterol linked to cardiovascular risk

Human stem cells restore motor function in chronic stroke patients

Advances in precision diagnostics aid accurate detection of CNS tumors

Retroviral replicating vector can extend lives of brain cancer patients

Multiple cell and gene therapies can enhance cardiac function in mice modeled with MI

CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory

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