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Newly discovered drug-like compound may revolutionize treatment of autoimmune diseases

University of Colorado Boulder researchers have discovered a potent, drug-like compound that could someday revolutionize treatment of rheumatoid arthritis and other autoimmune diseases by inhibiting a protein instrumental in prompting the body to start attacking its own tissue.

21 Nov 2017

Simple test could help predict best treatment for cystic fibrosis patients

Several cutting-edge treatments have become available in recent years to correct the debilitating chronic lung congestion associated with cystic fibrosis. While the new drugs are life-changing for some patients, they do not work for everyone.

21 Nov 2017

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

Serious liver and heart problems can affect children with Alagille Syndrome early in life. While there is as yet no cure, researchers at Karolinska Institutet in Sweden have discovered that the liver disease part of the syndrome is caused by specific malformations of the bile ducts.

21 Nov 2017

Heart disease risk factors linked to walking difficulties in people under age of 78

Problems with balance, walking speed, and muscle strength become more common as we age, and can lead to disability. In fact, studies show that for older adults, having a slower walking speed can help predict chronic illness, hospitalization, and even death.

21 Nov 2017

Uncontrolled lung diseases could lead to costly A&E visits and hospital stays

People with potentially fatal chronic lung diseases are not in control of their condition,new research by Chiesi reveals today. This could be leading to costly A&E visits and hospital stays which may be dramatically reduced if they were being treated adequately.

21 Nov 2017

Most older Americans prefer to actively participate in medical decision making

Although most older Americans prefer to actively participate in making health care decisions, those with four or more chronic conditions are less likely to prefer active decision making.

21 Nov 2017

Scientists develop new method to study Creutzfeldt-Jakob disease in the lab

Scientists have developed a new system to study Creutzfeldt-Jakob disease in the laboratory, paving the way for research to find treatments for the fatal brain disorder.

20 Nov 2017

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

D. Brent Polk, MD, AGAF, an investigator at Children's Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for the study of tumor necrosis factor (TNF) and its role in inflammatory bowel disease (IBD).

20 Nov 2017

Preclinical study shows clear path toward effective treatment for rare bone disease

Researchers at Sanford Burnham Prebys Medical Discovery Institute have led a preclinical study demonstrating that the drug palovarotene suppresses the formation of bony tumors (osteochondromas) in models of multiple hereditary exostoses (MHE).

20 Nov 2017

Patient-centered medical home model effective at improving chronic disease outcomes

Data from more than 800 Veterans Health Administration (VHA) primary care clinics revealed that national implementation of a patient-centered medical home model was effective at improving several chronic disease outcomes over time.

20 Nov 2017

Enterovirus vaccine protects against virus-induced diabetes in mouse model

Scientists at the University of Tampere and the Karolinska Institutet have demonstrated that an enterovirus vaccine can protect against virus-induced diabetes in a mouse model for Type 1 diabetes.

20 Nov 2017

Cystic fibrosis patients have more good and bad bacteria in their lungs, study finds

A large multicenter study found that patients with cystic fibrosis (CF) – who tend to develop chronic lung infections – had more good and bad bacteria in their lungs compared to controls.

20 Nov 2017

Experts endorse recommendations for restrictive blood transfusions

By analyzing data from randomized clinical trials comparing blood transfusion approaches, Johns Hopkins experts, along with colleagues at Cleveland Clinic and NYU Langone Medical Center, endorse recommendations for blood transfusions that reduce blood use to improve patient safety and outcomes.

20 Nov 2017

UZH leads Europe's largest research on aging

What began in 2012 is now entering its final stages: Europe's largest study on aging. The international research network behind the DO-HEALTH study is led by Heike Bischoff-Ferrari, Professor of Geriatric Medicine and Aging Research at the University of Zurich, and Head of the Department of Geriatrics at the UniversityHospital Zurich and the Waid City Hospital in Zurich, Switzerland.

20 Nov 2017

AAP and The Obesity Society jointly address weight stigma in childhood obesity

For youth with obesity and their families, weight stigma causes as much harm as obesity itself. It leads to bullying and raises the risk that a child with obesity will become an adult with obesity, along with a host of other chronic diseases. It makes the problem worse, not better.

20 Nov 2017

New studies highlight importance of cardiorespiratory fitness to reduce CVD risk

Coronary heart disease (CHD) is a leading cause of death for men in the U.S. Both cardiorespiratory fitness (CRF) and the blood triglyceride/high-density lipoprotein ratio (TG:HDL ratio) are strong predictors of death from CHD. In the current issue of Mayo Clinic Proceedings, two new studies highlight the importance of CRF on subsequent CVD and mortality risk.

17 Nov 2017