Immunohistochemistry News and Research

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Immunohistochemistry (IHC) is an imaging technique to visualize antigens in cells. Labeled antibodies bind to target antigens in the cell to image the distribution and localization of specific proteins of interest

Study reports persistent SARS-CoV-2 lingering within tissues of patients with long COVID

Researchers investigated whether residual SARS-CoV-2 antigens and RNA are present in tissues samples of long COVID-19 patients beyond the convalescent phase of COVID-19.

24 Feb 2022

Mouse-adapted virus model to study persistent COVID induced lung disease

Researchers develop a mouse model to identify early biomarkers and test countermeasures needed to detect and prevent PASC.

21 Feb 2022

Testes found to be a viral reservoir for SARS-CoV-2 replication

In a recent study posted to the medRxiv* pre-print server, researchers used a suite of methods to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the testis of patients who died from coronavirus disease 2019 (COVID-19) to gain insights into SARS-CoV-2 tropism inside testis and its impact on male fertility.

13 Feb 2022

Protective efficacy of BNT162b2 and Ad26.COV2.S against SARS-CoV-2 Omicron challenge in nonhuman primates

The study highlights the significance of mix-and-match vaccine regimens to diversify the immune responses against highly mutated variants of SARS-CoV-2 such as Omicron.

10 Feb 2022

Antibody drug improves survival rates in canine prostate cancer model

Dogs are proving to be a far better scientific model for study of prostate cancer than mice, the typical animal used in the lab for this type of research.

8 Feb 2022

Efficacy of MVA-CoV2-S vaccination to prevent SARS-CoV-2 cerebral infection and associated damage

Researchers demonstrated that an MVA vector expressing the SARS-CoV-2 spike protein was 100% effective in preventing neuroinvasion and brain damage by SARS-CoV-2 in transgenic mice.

8 Feb 2022

Better diagnostic tests needed to guide HER2 breast cancer treatment, study suggests

A new study by researchers at Yale Cancer Center shows using current standard human epidermal growth factor receptor 2 (HER2) assays as a diagnostic test may result in a mis-assignment of patients for treatment for breast cancer with a promising new drug.

3 Feb 2022

Relationship between SARS-CoV-2 neurotropism and Alzheimer's disease

In a new study, researchers evaluated the neurotropism of SARS-CoV-2 and its impact on COVID-19 patients with and without neurological disorders like Alzheimer's disease.

3 Feb 2022

Nanoparticle vaccine effective against eight SARS-CoV-2 variants in non-human primates

Researchers demonstrate that SARS-CoV-2 RBD-based nanoparticle vaccine induces neutralizing antibodies against SARS-CoV-2 variants.

2 Feb 2022

The Role of Glycans in the Cell and Glycans Imaging Method

In this interview, News-Medical talks to a pioneer of glycan imaging, Richard Drake about glycans, their role in maintaining cellular homeostasis, glycopeptide analysis, and method development for glycan imaging.

From Bruker Life Sciences Mass Spectrometry 26 Jan 2022

Human endogenous retrovirus type W envelope protein found to be a biomarker of COVID-19 severity

A new study revealed that the expression of HERV-W envelope protein (ENV) in lymphoid cells from COVID-19 patients correlated with disease outcome making them biomarkers of lymphocyte exhaustion.

24 Jan 2022

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

A new study focused on the pathomorphological and virological characterization of SARS-CoV-2 in naturally infected, wild Indian Leopard.

17 Jan 2022

Long-term use of blood pressure medication could be contributing to kidney damage

New kidney research from the University of Virginia School of Medicine is raising concerns that long-term use of drugs commonly prescribed to treat high-blood pressure and heart failure could be contributing to kidney damage.

12 Jan 2022

Researchers set the framework for improved colorectal cancer surveillance using precision medicine

A team of Vanderbilt researchers has revealed some of the mechanisms by which polyps develop into colorectal cancer, setting the framework for improved surveillance for the cancer utilizing precision medicine.

7 Jan 2022

SARS-CoV-2 appears to persist in organs throughout the body for months

The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leads to asymptomatic or mild symptoms in most cases. However, in a significant minority, it causes moderate or severe disease, with lung damage and sometimes multi-organ dysfunction, the origin of which is currently a matter of intense debate.

6 Jan 2022

Immunohistochemistry News and Research

Further Reading

Study reports persistent SARS-CoV-2 lingering within tissues of patients with long COVID

Mouse-adapted virus model to study persistent COVID induced lung disease

Testes found to be a viral reservoir for SARS-CoV-2 replication

Protective efficacy of BNT162b2 and Ad26.COV2.S against SARS-CoV-2 Omicron challenge in nonhuman primates

Antibody drug improves survival rates in canine prostate cancer model

Efficacy of MVA-CoV2-S vaccination to prevent SARS-CoV-2 cerebral infection and associated damage

Better diagnostic tests needed to guide HER2 breast cancer treatment, study suggests

Relationship between SARS-CoV-2 neurotropism and Alzheimer's disease

Nanoparticle vaccine effective against eight SARS-CoV-2 variants in non-human primates

The Role of Glycans in the Cell and Glycans Imaging Method

Human endogenous retrovirus type W envelope protein found to be a biomarker of COVID-19 severity

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

Long-term use of blood pressure medication could be contributing to kidney damage

Researchers set the framework for improved colorectal cancer surveillance using precision medicine

SARS-CoV-2 appears to persist in organs throughout the body for months

Scientists identify a panel of nanobodies with good neutralizing efficacy against SARS-CoV-2 variants of concern

Severe COVID-19 found to be associated with disrupted intestinal Peyer’s patches

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

Lunaphore highlights novel spatial biology research at SITC 2021

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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