Cytokine News and Research

RSS

Newly identified pathway controls dangerous overreactions in the body's immune system

Scientists at Sinai Health say they have discovered a new pathway that controls dangerous overreactions in a body's immune system, including deadly forms of hyper-inflammation.

26 Mar 2021

New study may shed light on inflammatory bowel disease

Researchers have found an unexpected synergy between a T-cell stimulatory protein -- the ICOS ligand -- and interleukin-10, an immunoregulatory cytokine, to prevent inflammatory bowel disease in mice.

26 Mar 2021

Study observes correlation between COVID-19 mortality and autoantibodies in corticosteroid treated patients

Corticosteroid anti-inflammatory drugs have been applied to COVID-19 patients over the course of the pandemic, though the results are mixed. In a recent study, the outcomes for such patients are collated, demonstrating a striking correlation between the development of autoantibodies and mortality.

25 Mar 2021

Dual-antigen COVID-19 vaccine elicits humoral and cellular immune responses in mice

The scientific consensus is that safe and highly effective vaccines are required to end the ongoing pandemic of coronavirus disease 2019 COVID-19, caused by SARS-CoV-2. A new study describes a new vaccine that presents two viral antigens to the human immune system, in order to elicit a more efficacious response.

25 Mar 2021

New therapeutic vaccine uses patient's own tumor cells to aid in cancer destruction

Immunotherapy, which recruits the body's own immune system to attack cancer, has given many cancer patients a new avenue to treat the disease.

24 Mar 2021

SARS-CoV-2 can cause persistent dendritic cell deficiencies

In a new study, the persistent influence of SARS-CoV-2 on dendritic cell deficiency seven months post-infection is asserted, and the mechanism of action investigated.

24 Mar 2021

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

A new study suggests that Sargramostim, a medication often used to boost white blood cells after cancer treatments, is also effective in treating and improving memory in people with mild-to-moderate Alzheimer's disease.

24 Mar 2021

Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function

A new study reports the essential nature of Fc-mediated functionalities in determining the efficacy of such antibodies.

24 Mar 2021

Changes in OASI gene expression increases risk of Alzheimer's and severe COVID-19 infection

Previous research identified the interferon-responsive OAS1 gene as a risk gene for Alzheimer's disease. OAS1 is an enzyme that binds to double-stranded RNA and induces the conformation to create oligoadenylates. They also activate RNase L to break down RNA.

23 Mar 2021

Dandelion extract inhibits SARS-CoV-2 in vitro

An exciting new study describes a specific inhibitor of the SARS-CoV-2 found in an extract of the common dandelion that could provide a new and fruitful avenue of drug research.

23 Mar 2021

Clofazimine inhibits coronaviruses including SARS-CoV-2, study finds

Researchers at the University of Hong Kong found that Clofazimine, a lipophilic antimicrobial riminophenazine dye used in combination with agents like rifampicin and dapsone to treat leprosy, inhibits coronaviruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19 disease.

21 Mar 2021

Circular RNA vaccine shows neutralizing activity against B.1.351 variant

New preclinical research led by Wensheng Wei from Peking University in China has proposed the development of a circular RNA vaccine. Their findings showed the circular RNA vaccine creates neutralizing antibodies and strong T-cell responses against the receptor-binding domain of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

21 Mar 2021

Acute exposure of lung tissue to vape aerosol has lesser impact on gene expression than cigarette smoke

A new peer-reviewed study published in the journal Toxicological Research & Application shows acute exposure of a 3D human bronchial tissue model to e-cigarette aerosol has minimal impact on gene expression compared to smoke from combustible cigarettes.

21 Mar 2021

Cytokine News and Research

Newly identified pathway controls dangerous overreactions in the body's immune system

New study may shed light on inflammatory bowel disease

Study observes correlation between COVID-19 mortality and autoantibodies in corticosteroid treated patients

Dual-antigen COVID-19 vaccine elicits humoral and cellular immune responses in mice

New therapeutic vaccine uses patient's own tumor cells to aid in cancer destruction

SARS-CoV-2 can cause persistent dendritic cell deficiencies

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function

Changes in OASI gene expression increases risk of Alzheimer's and severe COVID-19 infection

Dandelion extract inhibits SARS-CoV-2 in vitro

Clofazimine inhibits coronaviruses including SARS-CoV-2, study finds

Circular RNA vaccine shows neutralizing activity against B.1.351 variant

Acute exposure of lung tissue to vape aerosol has lesser impact on gene expression than cigarette smoke

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

Study reveals biomarkers for the prognosis of gastric adenocarcinoma

A modified protein mediates development of lung fibrosis after cadmium/carbon black exposure

Progesterone therapy may improve clinical outcomes for male COVID-19 patients

New study maps SARS-CoV-2 and host protein interactions in detail

Study reveals unknown immune defense system that protects the lungs from viral infections

Could cinnamon modulate the immune response in severe COVID-19?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News