Chronic News and Research

RSS

$EpilepsyGTx raises $33 million Series A to develop single dose gene therapy for focal refractory epilepsy$

EpilepsyGTx raises $33 million Series A to develop single dose gene therapy for focal refractory epilepsy

EpilepsyGTx, a biotechnology company focused on research and development of cutting-edge gene therapies to treat refractory epilepsy, today announced it has raised $33 million in a Series A financing to advance its lead program EPY201 through Phase 1/2a clinical trials.

10 Dec 2025

Pirtobrutinib shows superior outcomes compared to common first-line combination treatment for CLL/SLL

In a new trial, the Bruton tyrosine kinase (BTK) inhibitor pirtobrutinib increased the rate of survival without disease progression and was well tolerated with a more favorable safety profile when compared with bendamustine plus rituximab (BR) in patients with previously untreated chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL).

10 Dec 2025

National study maps where food additives come from in children’s and adults’ diets

By analysing nationally representative diet data, researchers show that food additives rarely occur alone, with children and teenagers experiencing the highest exposure to complex additive mixtures largely driven by ultra-processed foods.

9 Dec 2025

SIRT3 deficiency worsens eustachian tube dysfunction during middle-ear infection

Middle-ear infections caused by Gram-negative bacteria remain among the most common pediatric illnesses worldwide.

9 Dec 2025

Deaf women remain invisible in Scotland’s domestic abuse system, report warns

A new report warns Deaf women experiencing domestic abuse in Scotland remain "effectively invisible" due to the chronic absence of specialist services and a lack of coordinated national support.

9 Dec 2025

AI-driven method uncovers genetic interactions that fuel cancer progression

University of South Australia scientists have developed a powerful new way to uncover the genetic interactions that fuel cancer progression, paving the way for earlier and more precise treatments.

9 Dec 2025

Landmark RSI trial reshapes sedative selection for emergency airway management

Doctors treating seriously ill patients in an emergency setting may want to give the sedative etomidate, rather than ketamine, while placing a breathing tube, according to a randomized trial published in the New England Journal of Medicine.

9 Dec 2025

Gut microbe metabolite TMA improves blood sugar by shutting down a key inflammatory switch

Researchers identified trimethylamine (TMA) as a gut microbe–derived metabolite that directly inhibits IRAK4 to reduce metabolic inflammation and improve glycaemic control in high-fat-diet-fed mice. Choline-driven increases in TMA production replicated these benefits, revealing a host–microbe signaling axis with therapeutic potential for obesity-associated insulin resistance.

9 Dec 2025

Research ushers in a new era of hope for patients with primary immune thrombocytopenia

More than half of patients in a Phase III clinical trial who received a limited course of the experimental monoclonal antibody ianalumab for primary immune thrombocytopenia (ITP), an autoimmune disorder that can cause life-threatening bleeding, were able to maintain safe platelet counts without serious bleeding episodes for at least one year.

9 Dec 2025

Disinfectant used in water treatment may impact the incidence of Legionnaire's disease

Preliminary results of a nationwide study suggest that the disinfectant used to treat water before it is distributed through pipes may impact the incidence of Legionnaire's disease in certain parts of the country.

9 Dec 2025

New study could lead to quicker and more targeted support for vulvodyniaia

A first-of-its-kind University of Stirling-led study could lead to quicker and more targeted support for vulvodynia - a painful chronic condition estimated to affect more than one in 10 women with no known cause.

9 Dec 2025

Trump’s idea for health accounts has been tried. Millions of patients have ended up in debt.

Sarah Monroe once had a relatively comfortable middle-class life. She and her family lived in a neatly landscaped neighborhood near Cleveland. They had a six-figure income and health insurance. Then, four years ago, when Monroe was pregnant with twin girls, something started to feel off.

9 Dec 2025

Hotter days and nights are already stealing sleep across the U.S.

Rising nighttime and daytime temperatures are associated with reduced sleep duration, poorer sleep continuity, delayed sleep onset, and altered sleep stages in a large U.S. cohort tracked with wearable devices. Vulnerability is greatest among adults aged 40–50 years, females, people with lower socioeconomic status, chronic conditions, and those living in marine climate zones, with climate change projected to further magnify sleep loss.

8 Dec 2025

A 36-week screening strategy safely reduces pre-eclampsia at term

Screening pregnant women at 36 weeks using a validated risk model and offering risk-stratified planned early-term birth reduced the incidence of term pre-eclampsia by about 30 percent without increasing maternal or neonatal complications. The randomised PREVENT-PE trial demonstrates that a personalised timing-of-birth strategy can prevent term pre-eclampsia where no effective medical prevention currently exists.

8 Dec 2025

Lubiprostone shows signs of slowing kidney function decline in chronic kidney disease

In adults with stage IIIb–IV chronic kidney disease, the constipation drug lubiprostone did not reduce gut-derived uremic toxins but preserved creatinine-based kidney function over 24 weeks. The benefit was linked to microbiome remodeling, increased polyamine production, and improved mitochondrial function rather than toxin lowering.

8 Dec 2025

NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Adults with chronic pain who participated in New York State's (NYS) Medical Cannabis Program were significantly less likely to require prescription opioids, according to a new study published today in JAMA Internal Medicine and led by researchers at Albert Einstein College of Medicine and Montefiore Health System.

8 Dec 2025

Understanding the health hazards of ultrafine particles emitted by small electric home appliances

Small home appliances equipped with electric heating coils and brushed DC motors, like hair dryers, air fryers and toasters—can emit harmful tiny ultrafine particles that deteriorate indoor air quality.

8 Dec 2025

Sleep may hold the key to staying active

Getting enough sleep and staying active are two of the most important things we can do for our health, but new research shows that most people struggle to achieve both, and that sleep may hold the key to moving more.

8 Dec 2025

Lower dose of immunotherapy for malignant melanoma improves results

According to a new study, lower doses of approved immunotherapy for malignant melanoma can give better results against tumors, while reducing side effects.

8 Dec 2025

Noninvasive Raman device tracks blood glucose accurately in under a minute

MIT researchers developed a compact band-pass Raman spectroscopy device that noninvasively tracks glucose through the skin in under a minute using physically interpretable optical signals. In a pilot study and tissue phantom validation, the system showed glucose measurements comparable to commercial continuous glucose monitors, supporting further clinical evaluation.

7 Dec 2025

Previous
1
...
88
89
90
91
92
93
94
...
2072
Next

Chronic News and Research

EpilepsyGTx raises $33 million Series A to develop single dose gene therapy for focal refractory epilepsy

Pirtobrutinib shows superior outcomes compared to common first-line combination treatment for CLL/SLL

National study maps where food additives come from in children’s and adults’ diets

SIRT3 deficiency worsens eustachian tube dysfunction during middle-ear infection

Deaf women remain invisible in Scotland’s domestic abuse system, report warns

AI-driven method uncovers genetic interactions that fuel cancer progression

Landmark RSI trial reshapes sedative selection for emergency airway management

Gut microbe metabolite TMA improves blood sugar by shutting down a key inflammatory switch

Research ushers in a new era of hope for patients with primary immune thrombocytopenia

Disinfectant used in water treatment may impact the incidence of Legionnaire's disease

New study could lead to quicker and more targeted support for vulvodyniaia

Trump’s idea for health accounts has been tried. Millions of patients have ended up in debt.

Hotter days and nights are already stealing sleep across the U.S.

A 36-week screening strategy safely reduces pre-eclampsia at term

Lubiprostone shows signs of slowing kidney function decline in chronic kidney disease

NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Understanding the health hazards of ultrafine particles emitted by small electric home appliances

Sleep may hold the key to staying active

Lower dose of immunotherapy for malignant melanoma improves results

Noninvasive Raman device tracks blood glucose accurately in under a minute

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News