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Partially matched blood cells could help cure people with both cancer and HIV

Following the news that a third person has been cured of HIV, a Northwestern Medicine expert says partially matched blood cells could be used to cure many people living with both cancer and HIV.

21 Feb 2022

The logic that controls gene regulation in human cells discovered

A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge can be applied to, for example, investigating cancers and other genetic diseases.

21 Feb 2022

Researchers unravel essential final steps in the production of mRNA

Proteins need to interact in a complex manner for a so-called "messenger RNA" (mRNA) to be created in human cells from a precursor molecule. mRNA provides a blueprint for proteins; the first vaccines against the coronavirus are also based on mRNAs.

21 Feb 2022

TTUHSC expert wins NIH renewal grant to continue research on neurological disorders

According to the Global Burden of Disease study, neurological disorders are the leading cause of disability and the second leading cause of death after heart disease.

21 Feb 2022

Study offers new understanding of how the immune system reacts to COVID-19

Little has been known to date about how the immune system's natural killer (NK) cells detect which cells have been infected with SARS-CoV-2.

21 Feb 2022

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

A new review paper published in PLoS Pathogens discusses the new variants and the structural mechanism underlying antibody-mediated neutralization as well as mutational antibody escape.

21 Feb 2022

Mathematical model of host immune response to SARS-CoV-2 demonstrates that age-related risk factors increased viral load

Researchers evaluated the host immune responses to SARS-CoV-2 and its prolonged symptoms.

21 Feb 2022

Surfactant-containing oral mouthwashes target the lipid envelope of SARS-CoV-2

Researchers demonstrated the composition and importance of SARS-CoV-2 lipid envelope and assessed the antiviral potential of oral mouthwashes targeting these lipid envelopes.

21 Feb 2022

Biochemical changes in lung physiology not responsible for severe clinical outcomes in the older population

Researchers investigated whether age-dependent changes in lung physiology make the elderly disproportionately susceptible to SARS-CoV-2 infection.

21 Feb 2022

Mechanisms of IL-6 expression in peripheral monocyte-derived macrophages infected with SARS-CoV-2

Researchers examined the detailed mechanisms of ‘cytokine storm’ that induces ARDS, often resulting in the death of severely ill COVID-19 patients.

21 Feb 2022

HIV patient treated with blood stem cell transplant for leukemia achieves long-term remission

A patient living with HIV who received a blood stem cell transplant for high-risk acute myeloid leukemia has been free of the virus for 14 months after stopping HIV antiretroviral drug treatment, suggesting a cure, according to the Weill Cornell Medicine physician-scientists who performed the transplant and managed her care

21 Feb 2022

Insight into cellular waste disposal could lead to new treatments for neurodegenerative diseases

A 'waste collection' tidies up our cells. If something does not go according to plan, serious diseases such as Alzheimer's or Parkinson's may develop.

20 Feb 2022

Emergence of new HIV variant underscores importance of monitoring virus mutations

A new study published in the journal Science reported the presence of a subtype-B variant of HIV-1 with remarkably high virulence, circulating in the Netherlands during the past two decades.

20 Feb 2022

N-glycosylation blockers reduce SARS-CoV-2 infection

A new Virology study shows that the N-glycosylation pattern of SARS-CoV-2 is crucial to normal spike activity.

20 Feb 2022

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

A new study describes a potential new approach to treating COVID-19 in the form of single-chain fragment variable (scFv) antibodies.

20 Feb 2022

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

A new study explains how SARS-CoV-2 adapts its immunogenicity to the immune response of the host.

20 Feb 2022

The impact of SARS-CoV-2 on lipids

SARS-CoV-2 appears to alter host lipid biosynthesis by relying on certain human metabolic pathways to survive and multiply effectively.

20 Feb 2022

Structure of protein that can pump toxic molecules out of bacterial cells revealed

MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria become resistant to multiple antibiotics.

18 Feb 2022

T-cell responses linked with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer

T-cell responses directed against the receptor-binding domain of the SARS-CoV-2 spike protein were associated with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer, with lower T-cell responses observed in patients with blood cancers.

18 Feb 2022

Music therapy is beneficial for patients with sickle cell disease

A new study from University Hospitals (UH) Connor Whole Health found patients with Sickle Cell Disease (SCD) who participated in music therapy learned new self-management skills and improved their ability to cope with pain.

18 Feb 2022

Cell News and Research

Partially matched blood cells could help cure people with both cancer and HIV

The logic that controls gene regulation in human cells discovered

Researchers unravel essential final steps in the production of mRNA

TTUHSC expert wins NIH renewal grant to continue research on neurological disorders

Study offers new understanding of how the immune system reacts to COVID-19

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

Mathematical model of host immune response to SARS-CoV-2 demonstrates that age-related risk factors increased viral load

Surfactant-containing oral mouthwashes target the lipid envelope of SARS-CoV-2

Biochemical changes in lung physiology not responsible for severe clinical outcomes in the older population

Mechanisms of IL-6 expression in peripheral monocyte-derived macrophages infected with SARS-CoV-2

HIV patient treated with blood stem cell transplant for leukemia achieves long-term remission

Insight into cellular waste disposal could lead to new treatments for neurodegenerative diseases

Emergence of new HIV variant underscores importance of monitoring virus mutations

N-glycosylation blockers reduce SARS-CoV-2 infection

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

The impact of SARS-CoV-2 on lipids

Structure of protein that can pump toxic molecules out of bacterial cells revealed

T-cell responses linked with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer

Music therapy is beneficial for patients with sickle cell disease

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