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Researchers create a comprehensive atlas of cerebrovascular cell types

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

15 Feb 2022

New approach to alter the skin microbiome and reduce acne lesions using bacteria

Acne on the face is often treated with topical antibiotics, which tend to be used for an extended period of time and contribute to the serious problem of antibiotic resistance.

15 Feb 2022

Researchers find potential new strategy to treat metastatic form of intra-abdominal cancer

Researchers from the National Cancer Centre Singapore (NCCS) have found a potential new strategy to treat peritoneal carcinomatosis, a metastatic form of intra-abdominal cancer, where patients are presented with limited treatment options and poor overall survival.

15 Feb 2022

Incomplete repair of the damaged lung may contribute to death from COVID-19 and non-COVID ARDS

Investigators studying lung cells have discovered that the normal repair process that occurs after lung disease or injury appears to be incomplete but still ongoing in patients who died of COVID-19 and non-COVID acute respiratory distress syndrome (ARDS).

15 Feb 2022

Study lays the groundwork for developing novel ways to promote tissue regeneration

A study conducted at the University of Helsinki lays the groundwork for the development of future ways to promote tissue regeneration in, for example, degenerative diseases or accelerate recovery from tissue damage.

15 Feb 2022

Study reports higher years of life lost during the pandemic in deprived areas

The impact of the COVID-19 pandemic hit hardest in deprived areas of England and Wales, with excess years of life lost more than three times as high in the North West than the South West of England.

15 Feb 2022

Novel combination therapeutic approach could increase survival of pancreatic cancer patients

A novel combination treatment approach extended survival in mice with pancreatic cancer, demonstrating a potential second-line therapy for patients, according to findings published in Proceedings of the National Academy of Sciences.

15 Feb 2022

A third known case of HIV remission involving stem cell transplant documented

A woman with HIV who received a cord blood stem cell transplant to treat acute myeloid leukemia has had no detectable levels of HIV for 14 months despite cessation of antiretroviral therapy (ART), according to a presentation at today's Conference on Retroviruses and Opportunistic Infections (CROI).

15 Feb 2022

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

A new study published demonstrated the in vitro potencies of RDV and GS-441524 through PRA, and nucleoprotein ELISA against SARS-CoV-2 and other VOC/VOIs isolates with specific substitutions in Nsp12.

15 Feb 2022

Study investigates whether SARS-CoV-2 infection is associated with increased risk of incident type 1 diabetes

A recent study has demonstrated that although the incidence of type 1 diabetes increases among children during the COVID-19 pandemic, previous infection by SARS-CoV-2 does not directly act as a causal factor.

15 Feb 2022

Study describes sequelae presenting more than six months after COVID-19 in non-hospitalized young adults

A recent study described COVID-19 sequelae developed in non-hospitalized young adults more than six months after COVID-19 infection.

15 Feb 2022

Novel glycation patterns help understand Omicron immune escape

A new study explores changes in the sugar structure of the SARS-CoV-2 Omicron variant, which may shed light on its immunologic escape and transmissibility characteristics.

15 Feb 2022

Study suggests that epigenetic memory in innate immune cells could be the key to explaining long COVID

A new study may provide a partial explanation for the long-term immunologic phenomena associated with COVID-19.

15 Feb 2022

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

Single-cell RNA sequencing, or "scRNA-seq" for short, is a technique that allows scientists to study the expression of genes in an individual cell within a mixed population – which is virtually how all cells exist in the body's tissues.

15 Feb 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from Toronto, Canada, characterized the markers of endothelial function and developed micro ribonucleic acid (miRNA) expression atlas in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive and -negative patients admitted to the intensive care unit (ICU).

15 Feb 2022

Researchers generate stable cell lines capable of producing various hepatitis B virus genotypes

A new study created stable cell lines capable of producing different genotypes of the hepatitis B virus (HBV), advancing understanding of each type's distinct virological features, treatment responses, and infectivity that could lead to new therapies against a virus infecting humans as far back as 4,500 years ago.

15 Feb 2022

Cell News and Research

Researchers create a comprehensive atlas of cerebrovascular cell types

New approach to alter the skin microbiome and reduce acne lesions using bacteria

Researchers find potential new strategy to treat metastatic form of intra-abdominal cancer

Incomplete repair of the damaged lung may contribute to death from COVID-19 and non-COVID ARDS

Study lays the groundwork for developing novel ways to promote tissue regeneration

Study reports higher years of life lost during the pandemic in deprived areas

Novel combination therapeutic approach could increase survival of pancreatic cancer patients

A third known case of HIV remission involving stem cell transplant documented

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

Study investigates whether SARS-CoV-2 infection is associated with increased risk of incident type 1 diabetes

Study describes sequelae presenting more than six months after COVID-19 in non-hospitalized young adults

Novel glycation patterns help understand Omicron immune escape

Study suggests that epigenetic memory in innate immune cells could be the key to explaining long COVID

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

Researchers generate stable cell lines capable of producing various hepatitis B virus genotypes

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

Group cell movement could be harnessed to stop cancer spread, study suggests

First survey on Omicron BA.2 in France

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