Severe Acute Respiratory News and Research

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Researchers explore neurological manifestations among long COVID patients

In a new study, researchers assessed the long-term neurological sequelae in the post-acute phase of coronavirus disease 2019 (COVID-19) or long COVD.

26 Sep 2022

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

In a new study, researchers demonstrated how sarbecovirus family down-regulates major histocompatibility complex-I (MHC-I) surface expression to evade cellular immunity.

26 Sep 2022

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

In a new study, a team of researchers demonstrated that testicular injury in humans is not due to direct SARS-CoV-2 infection but more likely is an indirect effect of exposure to systemic inflammation or SARS-CoV-2 antigens.

26 Sep 2022

Study investigates long-range RNA-RNA interactions of SARS-CoV-2

Researchers explored RRIs [long-range ribonucleic acid (RNA)-RNA interactions] in SARS-CoV-2 variants of concern genomes to assess evolutionary changes in SARS-CoV-2.

26 Sep 2022

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

In a new study, researchers followed up with individuals vaccinated with a COVID-19 vaccine based on the mRNA platform up to six months following Omicron BA.1 breakthrough infection to trace the evolution of their antibody immunity.

26 Sep 2022

Resistance of Russian Rhinolophus bats containing ACE2-dependent sarbecoviruses to COVID-19 vaccines

In a new study, researchers investigated the receptor tropism and serological cross-reactivity for spike (S) protein receptor-binding domains from two clade 3 sarbecoviruses found in Russian Rhinolophus (horseshoe) bats.

26 Sep 2022

What is the association between body fat and COVID-19?

Researchers recently assessed the association between adipose tissues and COVID-19 by evaluating autopsy cases and profiling adipose tissue responses to SARS-CoV-2 infections.

26 Sep 2022

Long-term follow-up of young people with COVID-19 vaccine myocarditis

In a recent study, researchers surveyed a comprehensive range of outcomes in patients diagnosed with myocarditis after COVID-19 vaccination in the United States.

26 Sep 2022

How effective are live-attenuated SARS-CoV-2 vaccines?

Researchers opined on the use of live-attenuated whole virus vaccines as COVID-19 vaccines.

26 Sep 2022

Common germline variants of APOE contribute to differential COVID-19 outcomes

Researchers investigated the relationship between APOE4 genotype and COVID-19 outcomes using genetic models of mice.

26 Sep 2022

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Researchers presented the direct plasmid transfection method for SARS-CoV-2 virus-like particle production in insect cells and applied the VLPs to evaluate the efficacy of monoclonal antibodies and vaccinated donor sera.

26 Sep 2022

Study of 9 million Swedes shows rapidly declining effectiveness of COVID vaccines against Omicron

The findings of a new Swedish study posted to the Preprints with The Lancet* server found that two COVID-19 vaccine doses provided effective long-term protection against infection before Omicron, but less protection against Omicron infection (dropping to 43% by week four and no protection by week 14).

25 Sep 2022

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

In a recent study posted to the medRxiv* preprint server, researchers in the United States described the safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), tested in PREVENT-19 — a phase 3, randomized, placebo-controlled, observer-blinded trial among 12- to 17-year-old adolescents in the United States (U.S).

25 Sep 2022

How smallpox and monkeypox viruses affect the nervous system

A recent study provides an overview of existing literature on the complications of infection with both smallpox and monkeypox virus.

25 Sep 2022

Study describes the dynamics of immune responses to triple COVID-19 vaccination

The effectiveness of the three-dose COVID-19 vaccination against SARS-CoV-2 and its variants has been described in detail in a recent study.

23 Sep 2022

Study using circulating spike protein and macrophage dysregulation liquid biomarkers reveals heterogeneity in PASC

In a new study, researchers designed a liquid biomarker panel consisting of macrophage and monocyte-related soluble factors and circulating spike proteins to understand profiles of immune dysregulation in patients with post-acute sequelae of COVID-19.

22 Sep 2022

What role does cross-reactive immunity play in the spread of a novel SARS-CoV-2 variant?

In a new study, researchers used mathematical modeling to examine the effect of cross-reactive immunity from previous infections on an emerging SARS-CoV-2 variant, and explored the probability of the novel variant causing widespread infection or fading out.

22 Sep 2022

Severe Acute Respiratory News and Research

Researchers explore neurological manifestations among long COVID patients

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

Study investigates long-range RNA-RNA interactions of SARS-CoV-2

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

Resistance of Russian Rhinolophus bats containing ACE2-dependent sarbecoviruses to COVID-19 vaccines

What is the association between body fat and COVID-19?

Long-term follow-up of young people with COVID-19 vaccine myocarditis

How effective are live-attenuated SARS-CoV-2 vaccines?

Common germline variants of APOE contribute to differential COVID-19 outcomes

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Study of 9 million Swedes shows rapidly declining effectiveness of COVID vaccines against Omicron

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

How smallpox and monkeypox viruses affect the nervous system

Study describes the dynamics of immune responses to triple COVID-19 vaccination

Study using circulating spike protein and macrophage dysregulation liquid biomarkers reveals heterogeneity in PASC

What role does cross-reactive immunity play in the spread of a novel SARS-CoV-2 variant?

Does BA.2 breakthrough infection shift cross-neutralization activity towards the BA.4 and BA.5 Omicron sublineages?

Can a commercial breath analysis test detect SARS-CoV-2?

What is the efficacy of the BCG vaccine against SARS-CoV-2 infection?

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Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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