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How SARS-CoV-2 immune responses vary by population due to environmental and genetic factors

Researchers investigate the genetic, immunological, and evolutionary factors that determine the vast variability observed in clinical manifestations of COVID-19.

28 Nov 2022

New microfluidic Organ Chip platform replicates the human vaginal tissue microenvironment

The human microbiome has been a hot topic over the last decade, with research pointing to disrupted bacterial communities as culprits for a host of maladies including irritable bowel syndrome, eczema, and autoimmune diseases.

28 Nov 2022

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

In a new study, researchers developed two monkeypox (MPX) virus (MPXV) quadrivalent messenger ribonucleic acid (mRNA) vaccines, mRNA-A-lipid nanoparticle (LNP) and mRNA-B-LNP.

28 Nov 2022

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Researchers used cellular cryo-electron tomography (cryo-ET) to demonstrate the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in coronavirus disease 2019 (COVID-19)-triggered severe coagulopathies.

28 Nov 2022

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

In this interview, we speak to Axol Bioscience about their human iPSC-derived cells and how they have the potential to revolutionize the field of neurodegenerative disease.

From Axol Bioscience Ltd 28 Nov 2022

Feline coronavirus-infected domesticated cats found to possess cross-reactive anti-SARS-CoV-2 antibodies

In a recent study, researchers confirmed that feline coronavirus infection induced the production of cross-reactive antibodies against the SARS-CoV-2 receptor-binding domain in domestic cats.

28 Nov 2022

Flavonoids with potential to fight allergies and inflammation

In a recent study published in the Biomedicine & Pharmacotherapy journal, researchers explored the anti-allergic and anti-inflammatory properties of flavonoids.

28 Nov 2022

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

In a recent study published in The Journal of Immunology, a team of researchers from Japan examined the memory B and T cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein after the booster dose of the coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccine BNT162b2.

27 Nov 2022

How Can CPNs Revolutionize Medical Diagnostics?

At MEDICA 2022, NewsMedical spoke with Andy Chaloner about Stream Bio's conjugated polymer nanoparticle technologies that have the potential to revolutionize the medical and life sciences sectors, from diagnostics to clinical imaging.

From Stream Bio 25 Nov 2022

The relationship between neutralization levels and observed efficacies against asymptomatic and symptomatic infection of ten COVID-19 vaccines

Researchers determined whether neutralizing antibody levels were predictive of the efficacy of fractional vaccine doses against SARS-CoV-2 infection.

24 Nov 2022

Exploring synthetic engineering of bacteriophages

In a new study, researchers demonstrated biological bacteriophage containment and synthetic engineering.

24 Nov 2022

Can SARS-CoV-2 be inactivated by resonance caused by sound waves at the ultrasound frequency?

Researchers performed in vitro experiments to test the ability of different frequencies of ultrasound to inactivate SARS-CoV-2.

23 Nov 2022

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

BGI has currently published over 440 SCI (Science Citation Index) papers in the field of cancer research, with a cumulative impact factor of over 4,000 points.

From BGI Genomics 23 Nov 2022

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

In a recent study posted to the bioRxiv* preprint server, researchers in China demonstrated the efficacy of three messenger ribonucleic acid (mRNA) technology-based Monkeypox virus (MPXV) vaccines in combating a lethal Vaccinia virus (VACV) challenge in mice models.

22 Nov 2022

Ultrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as an immunotherapy

Zika virus (ZIKV) infection is a potentially teratogenic illness, causing up to one in seven infants born to infected mothers to suffer neurodevelopmental deficits. A new study published in the journal Cell shows that some mothers escape injury to their babies because they develop a highly potent neutralizing antibody.

22 Nov 2022

Study shows how HIV protein permanently alters immune cells

Though antiretroviral therapy has made HIV a manageable disease, people living with HIV often suffer from chronic inflammation.

22 Nov 2022

Microniches of intratumoral microbiota impact spatial and cellular heterogeneity in cancer

Researchers mapped spatial, cellular, and molecular interactions of host and tumor-associated bacteria within the tumor microenvironment.

22 Nov 2022

Creating New Targeted Antibacterial Products to Help Tackle Antimicrobial Resistance

We speak to Matthew Dunne, Director for Drug Discovery at Micreos Pharmaceuticals, about the importance of creating new targeted antibacterial products.

22 Nov 2022

The vaginal microbiome through the lens of systems biology

A new paper recently published online in Trends in Microbiology journal reviews the systems biology approach to explore the vaginal microbiome (VMB), helping to understand its composition and function and the mechanisms by which it interacts with the host.

22 Nov 2022

Using induced pluripotent stem cells to recreate the adrenal gland in a petri dish

Sitting atop the kidneys, the adrenal gland plays a pivotal role in maintaining a healthy body. Responding to signals from the brain, the gland secretes hormones that support critical functions like blood pressure, metabolism, and fertility.

21 Nov 2022

in vitro News and Research

How SARS-CoV-2 immune responses vary by population due to environmental and genetic factors

New microfluidic Organ Chip platform replicates the human vaginal tissue microenvironment

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

Feline coronavirus-infected domesticated cats found to possess cross-reactive anti-SARS-CoV-2 antibodies

Flavonoids with potential to fight allergies and inflammation

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

How Can CPNs Revolutionize Medical Diagnostics?

The relationship between neutralization levels and observed efficacies against asymptomatic and symptomatic infection of ten COVID-19 vaccines

Exploring synthetic engineering of bacteriophages

Can SARS-CoV-2 be inactivated by resonance caused by sound waves at the ultrasound frequency?

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

Ultrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as an immunotherapy

Study shows how HIV protein permanently alters immune cells

Microniches of intratumoral microbiota impact spatial and cellular heterogeneity in cancer

Creating New Targeted Antibacterial Products to Help Tackle Antimicrobial Resistance

The vaginal microbiome through the lens of systems biology

Using induced pluripotent stem cells to recreate the adrenal gland in a petri dish

Driving innovation in drug discovery with in vitro biology solutions eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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