Necrosis News and Research

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Overexpression of PEA-15 protein shrinks breast cancer tumors

Overexpression of PEA-15, which binds and drags an oncoprotein out of the cell nucleus where it fuels cancer growth, steeply reduced breast cancer tumors in a preclinical experiment, researchers at The University of Texas M. D. Anderson Cancer Center reported at the 100th annual meeting of the American Association for Cancer Research.

20 Apr 2009

Study looks at effect of transcatheter arterial chemoembolization on liver function

Recently, it has been demonstrated that Transcatheter arterial chemoembolization (TACE) improves survival compared with best supportive care in meta-analyses of randomized trials and in two individual clinical trials.

20 Apr 2009

Vitamin D deficiency is associated with inflammation in healthy women

According to a recent study in the Archives of Internal Medicine, 75 percent of Americans do not get enough Vitamin D.

9 Apr 2009

Trial of new biologic agent to treat psoriatic arthritis

Psoriatic arthritis affects about 11 percent of patients with psoriasis.

8 Apr 2009

Research looks at the elimination of hepatitis B and C

Two new studies in the April issue of Hepatology explore the ways that hepatitis B virus (HBV) and hepatitis C virus (HCV) can be cleared from patients' bodies.

1 Apr 2009

Cathepsin B increases apoptosis in fulminant hepatic failure

The traditional view is that hepatocyte necrosis is the main feature of fulminant hepatic failure, but increasing evidence implicates a dominant role for hepatocyte apoptosis in this pathogenesis.

22 Mar 2009

Trends in heart attack explained

Explaining trends in heart attack: prevention has improved, mortality rates are down, hospitalisation remains the same

11 Mar 2009

Immune system found to be more versatile than previously thought

By studying how mice fight off infection by intestinal worms - a condition that affects more than 1 billion people worldwide - scientists have discovered that the immune system is more versatile than has long been thought.

26 Feb 2009

Mice with "superhealing" powers provide clues to treating arthritis caused by traumatic injury

A strain of laboratory mice that has "superhealing" powers has been found to resist inflammation after a knee injury, and also to avoid developing arthritis at the injury site in the long term, according to researchers at Duke University Medical Center.

22 Feb 2009

First immune danger receptor' found

Cancer Research UK scientists have found the first biological receptor that alerts the immune system to 'dangerous' or abnormal cell death, according to research published in Nature.

16 Feb 2009

Inflammation may be the link between extreme sleep durations and poor health

A study in the Feb. 1 issue of the journal SLEEP shows that sleep duration is associated with changes in the levels of specific cytokines that are important in regulating inflammation.

2 Feb 2009

Cell transplantation and diabetes: New sites, new devices

Early attempts at islet cell transplantation to treat diabetes date to the nineteenth century, decades before the discovery of insulin in the 1930s.

21 Jan 2009

Active Hexose Correlated Compound shown to enhances immune system by increasing production of key dendritic cells

A recently published study in Nutrition and Cancer (60(5), 643-651) by researchers at Kansai Medical University in Osaka, Japan has shown that AHCC (Active Hexose Correlated Compound) enhances immune function by increasing the number of dendritic cells (DCs).

6 Jan 2009

Oral bisphosphonates linked to increased jaw necrosis

Researchers at the University Of Southern California, School Of Dentistry release results of clinical data that links oral bisphosphonates to increased jaw necrosis

1 Jan 2009

Magnetic nanotags allow sensitive detection of cancer biomarkers

The detection of cancer-associated proteins, or biomarkers, in blood samples is a potentially powerful tool for early diagnosis of cancer and monitoring of cancer treatment.

29 Dec 2008

Gene therapy used to treat periodontal disease

Scientists at the University of Michigan have shown that gene therapy can be used to successfully stop the development of periodontal disease, the leading cause of tooth loss in adults.

12 Dec 2008

Researchers create tiny, implantable device that captures and kills cancer cells in the bloodstream

In a new tactic in the fight against cancer, Cornell University researcher Michael King has developed what he calls a lethal "lint brush" for the blood -- a tiny, implantable device that captures and kills cancer cells in the bloodstream before they spread through the body.

12 Dec 2008

Studies examine quality of care for hospitalized sickle cell disease patients

A study assessing the quality of care for patients with sickle cell disease in a variety of hospital settings was presented Saturday, December 6 during the 50th Annual Meeting of the American Society of Hematology in San Francisco, CA.

8 Dec 2008

Rituxan in combination with chemo improves survival in chronic lymphocytic leukemia

Genentech, Inc. and Biogen Idec have announced that two global Phase III studies in chronic lymphocytic leukemia (CLL), CLL8 and REACH, showed Rituxan (rituximab) plus chemotherapy significantly increased the time patients lived without their disease advancing, as defined by the primary endpoint of progression-free survival (PFS), when compared to chemotherapy alone.

8 Dec 2008

Vitamin E supplementation may reduce inflammation in the brain

With up to half of a person's body mass consisting of skeletal muscle, chronic inflammation of those muscles - which include those found in the limbs - can result in significant physical impairment.

5 Dec 2008