Syndrome News and Research

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CHOP research offers insights into epilepsy, schizophrenia, other neuropsych disorders

Medical researchers have manipulated human stem cells into producing types of brain cells known to play important roles in neurodevelopmental disorders such as epilepsy, schizophrenia and autism.

3 May 2013

Viewpoints: Outrage at mistaken report on Hill health coverage; Two views of Florida's option on Medicaid

Because members of Congress are accustomed to high-quality medical care provided to them through federal employee benefit programs, one might expect that they would push for top quality care to be delivered through the exchanges too.

2 May 2013

Hypothalamus controls aging throughout the body, scientists report

While the search continues for the Fountain of Youth, researchers may have found the body's "fountain of aging": the brain region known as the hypothalamus.

2 May 2013

Schizophrenia cardiovascular risk under-recognized in primary care

UK researchers have found that despite being a major contributor to premature deaths among patients with schizophrenia, cardiovascular disease is less likely to be recorded on their primary care records than those of people without schizophrenia.

30 Apr 2013

Naturopathic lifestyle counselling helps reduce risk of cardiovascular disease

Counselling and treatment with naturopathic care as well as enhanced usual care reduced the prevalence of metabolic syndrome, a risk factor for heart disease, by 17% over a year for participants in a randomized controlled trial published in CMAJ.

30 Apr 2013

Targeted therapy prevents rare neurodevelopmental disorder seizures

Rapamycin treatment reduces seizure frequency and improves receptive language in patients with polyhydramnios, megalencephaly, and symptomatic epilepsy syndrome, or Pretzel syndrome, a study finds.

29 Apr 2013

Continuous monitoring flags acute compartment syndrome

Continuous intracompartmental pressure monitoring is highly accurate for the detection of acute compartment syndrome after tibial diaphyseal fracture, say UK researchers who believe it may allow diagnosis before signs and symptoms occur.

29 Apr 2013

Evidence shows progerin induced by ultraviolet light is responsible for premature skin aging

A study conducted by researchers at Boston University School of Medicine (BUSM) provides new evidence that longwave ultraviolet light (UVA) induces a protein that could result in premature skin aging.

26 Apr 2013

Researchers call H7N9 bird flu strain 'one of the most lethal'; first case outside China reported by Taiwan

Chinese scientists have confirmed for the first time that a new strain of bird flu that has killed 23 people in China has been transmitted to humans from chickens.

26 Apr 2013

GI nematode infections combat obesity and improve related metabolic disorders

Researchers at the University of Maryland School of Medicine, Baltimore, have shown in a mouse model that infection with nematodes (also known as roundworms) can not only combat obesity but ameliorate related metabolic disorders.

26 Apr 2013

Nature editorial, opinion piece address H7N9 virus

The journal Nature published an editorial and opinion piece on the emergence of the H7N9 avian influenza strain.

26 Apr 2013

Mayo Clinic implements electronic warning system to identify patients at risk of QT-related deaths

Using a one-of-a-kind computer-aided program, Mayo Clinic has developed and implemented a Mayo-wide electronic warning system to identify patients at risk of QT-related deaths from an abnormality in the heart's electrical system.

26 Apr 2013

Combinations of sEH inhibition and PPARγ activation have beneficial effects on cardiometabolic syndrome

Scientists at the Medical College of Wisconsin and the University of California at Davis, led by Dr. John Imig and Dr. Bruce Hammock have determined the synergistic actions of inhibiting soluble epoxide hydrolase (sEH) with tAUCB (trans-4-(4-[3-adamantan-1-yl-ureid]-cyclohexyloxy)-benzoic acid) and activating peroxisome proliferator-activator receptorγ (PPARγ) with the thiazolidinedione rosiglitazone on the pathological progression of cardiometabolic syndrome.

25 Apr 2013

Schizophrenia cardiovascular risk under-recognized in primary care

25 Apr 2013

Diagnostic hallmarks of POTS identified

US researchers have identified a constellation of symptoms that are associated with a diagnosis of postural tachycardia syndrome in adolescent patients with headache.

25 Apr 2013

Dietary substitution of saturated fats enriched in MCT prevents liver disease

Scientists at the Arkansas Children's Nutrition Center, a U.S. Department of Agriculture Agricultural Research Service Human Nutrition Research Center at the University of Arkansas for Medical Sciences, led by Dr. Martin Ronis have determined that dietary substitution of saturated fats enriched in medium chain triglycerides (MCT) for polyunsaturated fat prevents the development of nonalcoholic fatty liver disease (NAFLD).

25 Apr 2013

Sirolimus effective in treating children with Pretzel syndrome, new study reports

With a better understanding of underlying mechanisms that cause a rare neurodevelopmental disorder in the Old Order Mennonite population, referred to as Pretzel syndrome, a new study reports that five children were successfully treated with a drug that modifies the disease process, minimizing seizures and improving receptive language.

25 Apr 2013

Individuals with MEN1 are at increased risk of developing neuroendocrine tumors

A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1).

25 Apr 2013

Viewpoints: Time to confirm Tavenner; 'Self-defeating' GOP plan for prevention fund; Parents need insurance too

The Senate Finance Committee is scheduled to hold a long-overdue vote on Tuesday on President Obama's nominee to lead the embattled agency responsible for overseeing Medicare, Medicaid and the implementation of health care reforms.

24 Apr 2013

Sucampo's supplemental new drug application for AMITIZA gets FDA approval

Sucampo Pharmaceuticals, Inc. and Takeda Pharmaceuticals U.S.A., Inc. announced today that the United States Food and Drug Administration has approved Sucampo's supplemental new drug application for AMITIZA (lubiprostone) (24 mcg twice daily) as the first and only oral medication for the treatment of opioid-induced constipation in adult patients with chronic, non-cancer pain.

24 Apr 2013

Syndrome News and Research

CHOP research offers insights into epilepsy, schizophrenia, other neuropsych disorders

Viewpoints: Outrage at mistaken report on Hill health coverage; Two views of Florida's option on Medicaid

Hypothalamus controls aging throughout the body, scientists report

Schizophrenia cardiovascular risk under-recognized in primary care

Naturopathic lifestyle counselling helps reduce risk of cardiovascular disease

Targeted therapy prevents rare neurodevelopmental disorder seizures

Continuous monitoring flags acute compartment syndrome

Evidence shows progerin induced by ultraviolet light is responsible for premature skin aging

Researchers call H7N9 bird flu strain 'one of the most lethal'; first case outside China reported by Taiwan

GI nematode infections combat obesity and improve related metabolic disorders

Nature editorial, opinion piece address H7N9 virus

Mayo Clinic implements electronic warning system to identify patients at risk of QT-related deaths

Combinations of sEH inhibition and PPARγ activation have beneficial effects on cardiometabolic syndrome

Schizophrenia cardiovascular risk under-recognized in primary care

Diagnostic hallmarks of POTS identified

Dietary substitution of saturated fats enriched in MCT prevents liver disease

Sirolimus effective in treating children with Pretzel syndrome, new study reports

Individuals with MEN1 are at increased risk of developing neuroendocrine tumors

Viewpoints: Time to confirm Tavenner; 'Self-defeating' GOP plan for prevention fund; Parents need insurance too

Sucampo's supplemental new drug application for AMITIZA gets FDA approval

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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