Laboratory News and Research

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Scientists identify gene variants causing unrecognized developmental disorder

An international team of scientists has identified variants of the gene EBF3 causing a developmental disorder with features in common with autism.

22 Dec 2016

OIST researchers create novel sensor that detects biomolecules

OIST researchers create a novel sensor capable of measuring both charge and mass of biomolecules with potential applications in healthcare diagnostics.

22 Dec 2016

Tau biomarker could lead to early identification of Alzheimer's disease pathology

A discovery of high relevance in medical research will be published in Volume 55, number 4 of December 2016 of the prestigious "Journal of Alzheimer's Disease (JAD)", entitled "Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer's Disease".

22 Dec 2016

Canadian-Israeli researchers develop new biological pacemaker

Using human embryonic stem cells to create a type of cardiac cells known as sinotrial (SA) node pacemaker cells, a team of scientists from Israel and Canada have developed a biological pacemaker that overcomes many of the limitations of electrical pacemakers.

22 Dec 2016

UConn researchers develop new test to identify 'hidden' hearing deficits

Two researchers at UConn School of Medicine have developed a new hearing test that can identify hearing loss or deficits in some individuals considered to have normal or near-normal hearing in traditional tests.

22 Dec 2016

New study explores circadian timekeeping to create genetic knock-out rescue mice

A new study from the laboratory of Hiroki Ueda at the RIKEN Quantitative Biology Center investigates circadian timekeeping with a novel approach to creating genetic knock-out rescue mice.

22 Dec 2016

Researchers use mathematical models to explain how bacteria, cancer cells exploit bet-hedging

Modern medicine and treatments for bacterial infections and cancer have significantly increased life spans and improved quality-of-life. However, many drugs eventually fail because of the outgrowth and survival of treatment-resistant populations.

22 Dec 2016

Groundbreaking research finds concussion biomarker in auditory system

The secret to reliably diagnosing concussions lies in the brain's ability to process sound, according to a new study by researchers from Northwestern University's Auditory Neuroscience Laboratory.

22 Dec 2016

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment.

22 Dec 2016

Scientists find explanation for vulnerability of children to collateral damage from cancer treatment

Despite many successes in treating pediatric cancer, young children remain at high risk for developing severe, long-lasting impairments in their brain, heart, and other vital organs from chemotherapy and radiation treatments. In adults, however, these tissues are relatively spared.

22 Dec 2016

Simple listening tactic could benefit cochlear implant users in noisy social settings

Listeners in a noisy situation benefit from facing slightly away from the person they are listening to, turning one ear towards the speech, concludes a study by Cardiff University, funded by UK charity Action on Hearing Loss (RNID).

22 Dec 2016

Clinical Genomics introduces new blood-based test for CRC recurrence monitoring

Clinical Genomics, a private company developing evidence-based diagnostic tools for colorectal cancer, today announced the launch of Colvera, a blood-based test for colorectal cancer (CRC) recurrence monitoring. Colvera is the result of a decade of research, development and clinical validation in more than 4,000 patients.

22 Dec 2016

New research offers valuable insight for developing more effective drugs to treat IBD

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis.

22 Dec 2016

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Diet-related diseases like non-alcoholic fatty liver disease (NAFLD) are known to have a major inflammatory component.

21 Dec 2016

Dual treatment strategies lengthen lives of mice with skin cancer

By combining two treatment strategies, both aimed at boosting the immune system's killer T cells, Johns Hopkins researchers report they lengthened the lives of mice with skin cancer more than by using either strategy on its own.

21 Dec 2016

FDA expands approved use of G5 Mobile Continuous Glucose Monitoring System

The U.S. Food and Drug Administration today expanded the approved use of Dexcom's G5 Mobile Continuous Glucose Monitoring System to allow for replacement of fingerstick blood glucose (sugar) testing for diabetes treatment decisions in people 2 years of age and older with diabetes.

21 Dec 2016

Wellcome Trust Sanger Institute establishes spin-out company, Microbiotica

Cambridge Innovation Capital plc, a Cambridge-based investor in technology and healthcare companies, and IP Group plc, the developer of intellectual property-based businesses, announce the creation of Microbiotica Ltd, a newly formed spin-out company from the UK’s Wellcome Trust Sanger Institute based at the Wellcome Genome Campus in Hinxton, Cambridge.

21 Dec 2016

UT Southwestern researchers find new way to combat multidrug-resistant bacteria in burn injuries

A new way to fight multidrug-resistant bacteria by blinding them rather than killing them proved highly effective in a model of burn injuries, UT Southwestern Medical Center research shows.

21 Dec 2016

Scientists detail structure of molecule implicated in Alzheimer's disease

Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer's disease.

21 Dec 2016

Clinical study tests adult stem cell therapy for infants with congenital HLHS

In a first-in-children randomized clinical study, medical researchers at the University of Maryland School of Medicine and the Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine have begun testing to see whether adult stem cells derived from bone marrow benefit children with the congenital heart defect hypoplastic left heart syndrome (HLHS).

21 Dec 2016

Laboratory News and Research

Scientists identify gene variants causing unrecognized developmental disorder

OIST researchers create novel sensor that detects biomolecules

Tau biomarker could lead to early identification of Alzheimer's disease pathology

Canadian-Israeli researchers develop new biological pacemaker

UConn researchers develop new test to identify 'hidden' hearing deficits

New study explores circadian timekeeping to create genetic knock-out rescue mice

Researchers use mathematical models to explain how bacteria, cancer cells exploit bet-hedging

Groundbreaking research finds concussion biomarker in auditory system

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

Scientists find explanation for vulnerability of children to collateral damage from cancer treatment

Simple listening tactic could benefit cochlear implant users in noisy social settings

Clinical Genomics introduces new blood-based test for CRC recurrence monitoring

New research offers valuable insight for developing more effective drugs to treat IBD

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Dual treatment strategies lengthen lives of mice with skin cancer

FDA expands approved use of G5 Mobile Continuous Glucose Monitoring System

Wellcome Trust Sanger Institute establishes spin-out company, Microbiotica

UT Southwestern researchers find new way to combat multidrug-resistant bacteria in burn injuries

Scientists detail structure of molecule implicated in Alzheimer's disease

Clinical study tests adult stem cell therapy for infants with congenital HLHS

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