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New biomarkers can predict HIV remission after antiretroviral therapy interruption

New biomarkers that predict HIV remission after antiretroviral therapy (ART) interruption are critical for the development of new therapeutic strategies that can achieve infection control without ART, a condition defined as functional cure.

29 Jun 2021

Researchers show how Covid-19 changes the size and stiffness of red and white blood cells

Using real-time deformability cytometry, researchers at the Max-Planck-Zentrum für Physik und Medizin in Erlangen were able to show for the first time: Covid-19 significantly changes the size and stiffness of red and white blood cells - sometimes over months.

29 Jun 2021

Covid-19 patients experience a longer lasting reduced sense of taste and smell

Patients with mild Covid-19 infections experience a significantly increased longer lasting reduced sense of taste and smell.

29 Jun 2021

Six antibody features could be used to identify women at risk of placental malaria

Six antibody characteristics could help scientists identify which pregnant women are at risk of placental malaria infections, finds a study published today in eLife.

29 Jun 2021

Heart attacks during COVID-19 pandemic more likely to result in worse outcomes

Heart attacks during the COVID-19 pandemic were more likely to result in heart failure compared with heart attacks one year earlier, according to research presented today at Heart Failure 2021, an online scientific congress of the European Society of Cardiology.

29 Jun 2021

BUSM receives $2.7 million grant to reduce disparities in cardio-oncology

With a growing need to better understand the many links between heart disease and cancer, the two leading causes of death worldwide, the American Heart Association, the world's leading voluntary organization dedicated to a world of longer, healthier lives, announced grants focused on this area of scientific research.

29 Jun 2021

New study investigates alternative ways to prevent, treat kidney infections

Ten IU School of Medicine researchers out of a team of 11 scientists, are responsible for the findings of a new study they conducted to investigate alternative ways to treat kidney infections.

29 Jun 2021

IU School of Medicine wins $30 million NIA funding to study Alzheimer’s disease and related dementias

National Centralized Repository for Alzheimer's Disease and Related Dementias grant has been renewed for another five years with funding expected to total $30 million from the National Institute on Aging (NIA), within the National Institutes of the Health.

29 Jun 2021

Researchers examine whether community administration of ivermectin influences malaria transmission

Researchers from the LSTM based Cochrane Infectious Disease Group explored whether community administration of ivermectin influences malaria transmission.

29 Jun 2021

More evidence that mixing COVID-19 vaccines may help elicit a robust immune response

Eight volunteers who received a complete dose or a single dose of an mRNA vaccine or the ChAdOx1 vaccine after a dose of a trial gorilla adenovirus vaccine showed a significantly high level of antibodies and T cell response against SARS-CoV-2.

29 Jun 2021

Early testing can help mitigate blood clots related to AstraZeneca/Oxford vaccine

New research has shown that early testing for blood clots in patients who had received the AstraZeneca/Oxford vaccine led to them being treated successfully, highlighting the need for heightened awareness of the risk among doctors.

29 Jun 2021

Without enough boots on the ground, California’s vaccination efforts falter

Gov. Gavin Newsom routinely boasts that California has "one of the highest vaccination rates in the United States of America."

29 Jun 2021

Analysis: Why we’ll likely never know whether a covid lab leak happened in China

Early in this century, post-SARS, and in a period when China started allowing more students and scientists to study abroad, collaboration and exchange between American and Chinese scientists blossomed.

29 Jun 2021

Findings suggest that the cross-linking of fibrin proteins is key to reducing blood clot formation

Researchers have found that the y cross-chain structure of fibrin proteins is essential to stabilizing blood clots that can lead to harmful embolism formation.

29 Jun 2021

Scientists mimic the natural development of mammal using stem cells

The tiny mouse embryo has a heart that beats. Its muscles, blood vessels, gut and nervous system are beginning to develop. But this embryo is unusual: It was made in a lab, out of mouse embryonic stem cells, and represents the most sophisticated in vitro (in a dish) model of a mammal ever so created.

29 Jun 2021

New spider web mechanism kills pathogens and virus responsible for COVID-19

Immunologists at McMaster University have discovered a previously unknown mechanism which acts like a spider web, trapping and killing pathogens such as influenza or SARS-CoV-2, the virus responsible for COVID-19.

29 Jun 2021

H69/V70 deletion in Alpha variant enables SARS-CoV-2 to overcome chinks in its armor

One of the key mutations seen in the 'Alpha variant' of SARS-CoV-2 - the deletion of two amino acids, H69/V70 - enables the virus to overcome chinks in its armor as it evolves, say an international team of scientists.

29 Jun 2021

UPMC expert finds successful treatment for rare diseases diagnosed by newborn screenings

1It was a nagging mystery: A rare-disease expert at UPMC Children's Hospital of Pittsburgh had found a successful treatment for two of the deadliest symptoms of one of the more common classes of rare diseases diagnosed by newborn screenings, but one symptom--painful episodes of muscle breakdown that land victims in intensive care--persisted.

29 Jun 2021

Acidic environment enhances production of butyric acid from apple pectin by fecal microbiota

Researchers from Tallinn University of Technology, Grete Raba, Signe Adamberg, and Kaarel Adamberg showed that an acidic environment enhances the production of butyric acid from apple pectin by fecal bacterial consortia - microbiota.

29 Jun 2021

New study reveals how heparan sulfate promotes amyloid deposition in various organs

Amyloid diseases, including Alzheimer's, Parkinson's, type-2 diabetes and other life-threatening diseases, involve pathologic deposits of normally soluble proteins or peptides as insoluble amyloid fibrils. When this happens in vital organs, such as the brain, kidney, liver and heart, it causes organ damage and, if left untreated, death. Unfortunately, the available treatment options are very limited.

29 Jun 2021

Blood News and Research

New biomarkers can predict HIV remission after antiretroviral therapy interruption

Researchers show how Covid-19 changes the size and stiffness of red and white blood cells

Covid-19 patients experience a longer lasting reduced sense of taste and smell

Six antibody features could be used to identify women at risk of placental malaria

Heart attacks during COVID-19 pandemic more likely to result in worse outcomes

BUSM receives $2.7 million grant to reduce disparities in cardio-oncology

New study investigates alternative ways to prevent, treat kidney infections

IU School of Medicine wins $30 million NIA funding to study Alzheimer’s disease and related dementias

Researchers examine whether community administration of ivermectin influences malaria transmission

More evidence that mixing COVID-19 vaccines may help elicit a robust immune response

Early testing can help mitigate blood clots related to AstraZeneca/Oxford vaccine

Without enough boots on the ground, California’s vaccination efforts falter

Analysis: Why we’ll likely never know whether a covid lab leak happened in China

Findings suggest that the cross-linking of fibrin proteins is key to reducing blood clot formation

Scientists mimic the natural development of mammal using stem cells

New spider web mechanism kills pathogens and virus responsible for COVID-19

H69/V70 deletion in Alpha variant enables SARS-CoV-2 to overcome chinks in its armor

UPMC expert finds successful treatment for rare diseases diagnosed by newborn screenings

Acidic environment enhances production of butyric acid from apple pectin by fecal microbiota

New study reveals how heparan sulfate promotes amyloid deposition in various organs

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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