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Researchers identify multiple genetic variants associated with body fat distribution

A new breakthrough from the Genetic Investigation of Anthropometric Traits consortium, which includes many public health researchers from the University of North Carolina at Chapel Hill, identifies multiple genetic variants associated with how the body regulates and distributes body-fat tissue.

18 Feb 2019

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally "invisible" to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants.

18 Feb 2019

Researchers report progress in the treatment of aggressive brain tumors

Cancer researchers at the University of Bonn have reported significant progress in the treatment of glioblastoma. About one third of all patients suffer from a particular variant of this most common and aggressive brain tumor.

18 Feb 2019

Drug combinations could become first-line treatment for metastatic kidney cancer

A combination of two drugs - one of them an immunotherapy agent - could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial.

18 Feb 2019

Columbia researchers unravel why some glioblastomas respond to immunotherapy

Columbia researchers have learned why some glioblastomas--the most common type of brain cancer--respond to immunotherapy. The findings could help identify patients who are most likely to benefit from treatment with immunotherapy drugs and lead to the development of more broadly effective treatments.

17 Feb 2019

Chilean food regulations are changing food perceptions and purchasing habits, study suggests

Food regulations targeted at reducing obesity make a positive impact on those most likely to purchase the family's food - mothers.

17 Feb 2019

Children with ASD more likely to face maltreatment, study finds

A recent study by Vanderbilt researchers of 11 counties in Middle Tennessee revealed that children with autism spectrum disorder were nearly 2.5 times more likely than children without ASD to be reported to the Child Abuse Hotline by the age of 8.

15 Feb 2019

MUSC researchers discover new mechanism for a class of anti-cancer drugs

Researchers at the Medical University of South Carolina reveal a novel binding site for a class of anti-cancer drugs known as E1 inhibitors. This finding could lead to the design of more efficient E1 inhibitors.

15 Feb 2019

New technique using patients' own modified cells could help treat Crohn's disease

A new technique using patients' own modified cells to treat Crohn's disease has been proven to be effective in experiments using human cells, with a clinical trial of the treatment expected to start in the next six months.

15 Feb 2019

Excessive daytime sleepiness in OSA patients linked to greater risk for cardiovascular diseases

Adults with obstructive sleep apnea (OSA) who experience excessive sleepiness while awake appear to be at far greater risk for cardiovascular diseases than those without excessive daytime sleepiness, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

15 Feb 2019

Therapeutic endoscopy has an expanding role in the treatment of IBD

According to a new statement from a panel of national and international experts in gastroenterology, inflammatory bowel disease (IBD) and other areas, interventional (or therapeutic) IBD endoscopy has an expanding role in the treatment of disease and of adverse events from surgery.

15 Feb 2019

New injury documentation tool may provide better evidence for elder abuse cases

An estimated 10 percent of older adults experience some form of abuse each year. However, the link between injuries and possible elder abuse may take months or years to establish and is often difficult to investigate due to poor documentation during prior medical visits.

15 Feb 2019

High-protein and low-calorie diet helps older adults lose weight safely, shows study

A high-protein, low-calorie diet helps older adults with obesity lose more weight, maintain more muscle mass, improve bone quality and lose "bad" fat, according to results from a new randomized controlled trial led by Wake Forest University researcher Kristen Beavers.

15 Feb 2019

Moffitt researchers shed light on how CAR T cells function mechanistically

The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that activates a patient's own immune system to target cancer cells.

15 Feb 2019

Decolonization protocol after hospital discharge can prevent dangerous infections

Hospital patients who have methicillin-resistant Staphylococcus aureus can prevent future MRSA infections by following a standard bathing protocol after discharge, according to research results published in the February 14 issue of the New England Journal of Medicine.

15 Feb 2019

Researchers study animal venoms to identify new medicines for treating diseases

Animal venoms are the subject of study at research center based at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets of diseases and, armed with that knowledge, develop new compounds that can be used as medicines.

15 Feb 2019

New therapeutic molecules show promise in reversing memory loss related to depression, aging

New therapeutic molecules developed at Toronto's Centre for Addiction and Mental Health show promise in reversing the memory loss linked to depression and aging.

15 Feb 2019

Personal, social factors play role in enabling sustainable return to work after ill health

Support from managers and colleagues, as well as a positive attitude, are most likely to enable a more long-term return to work for employees after a sickness absence, according to a new review of research led by the University of East Anglia.

15 Feb 2019

Depression prevention for pregnant women and new mothers – new recommendations

At present all new mothers are screened for symptoms of depression and help is provided to those who need care. The U.S. Preventive Services Task Force now has urged doctors to screen pregnant women for risks of depression and provide adequate counselling and support to prevent the onset of depression after delivery. The report was published in the Journal of the American Medical Association this week.

14 Feb 2019

Self-reported sleep duration is a useful tool to measure sleep in children, study suggests

While sleep questionnaires are commonly completed by children and their parents, there has been a lack of data comparing the validity of these self-reported sleep parameters. A new study indicates that these sleep characteristics are relatively accurate compared to one another, and they vary only slightly from objective sleep measures.

14 Feb 2019

Education News and Research

Researchers identify multiple genetic variants associated with body fat distribution

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

Researchers report progress in the treatment of aggressive brain tumors

Drug combinations could become first-line treatment for metastatic kidney cancer

Columbia researchers unravel why some glioblastomas respond to immunotherapy

Chilean food regulations are changing food perceptions and purchasing habits, study suggests

Children with ASD more likely to face maltreatment, study finds

MUSC researchers discover new mechanism for a class of anti-cancer drugs

New technique using patients' own modified cells could help treat Crohn's disease

Excessive daytime sleepiness in OSA patients linked to greater risk for cardiovascular diseases

Therapeutic endoscopy has an expanding role in the treatment of IBD

New injury documentation tool may provide better evidence for elder abuse cases

High-protein and low-calorie diet helps older adults lose weight safely, shows study

Moffitt researchers shed light on how CAR T cells function mechanistically

Decolonization protocol after hospital discharge can prevent dangerous infections

Researchers study animal venoms to identify new medicines for treating diseases

New therapeutic molecules show promise in reversing memory loss related to depression, aging

Personal, social factors play role in enabling sustainable return to work after ill health

Depression prevention for pregnant women and new mothers – new recommendations

Self-reported sleep duration is a useful tool to measure sleep in children, study suggests

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