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Synageva BioPharma, to-BBB to evaluate brain drug delivery technology

Synageva BioPharma Corp. and to-BBB technologies BV, the Dutch drug brain delivery company, have entered into a research collaboration to evaluate the potential of transporting therapeutic proteins across the blood-brain barrier into the central nervous system.

6 Jan 2011

Studies show XIFAXAN 550 mg tablets demonstrate significant relief of global IBS symptoms

Salix Pharmaceuticals, Ltd. today announced the New England Journal of Medicine has published results from TARGET 1 and TARGET 2, the Company's two pivotal Phase 3 efficacy and safety studies of XIFAXAN (rifaximin) 550 mg tablets for the treatment of Irritable Bowel Syndrome without constipation, or Non-C IBS.

6 Jan 2011

Sudan referendum approaches, highlighting health, development challenges facing the south

"Southern Sudan is scheduled to start voting on January 9 on whether to become an independent country or remain part of Sudan, Africa's largest nation which has been wracked by decades of conflict," CNN reports (Wilkinson, 1/5).

6 Jan 2011

First web-based TBI screening tool for veterans

A team of researchers at Mount Sinai School of Medicine has developed the first web-based screening tool for Traumatic Brain Injury. This instrument has recently been used by soldiers returning from the wars in Iraq and Afghanistan who participated in the Sixth Annual Road to Recovery Conference and Tribute in Orlando to determine if they sustained a TBI.

6 Jan 2011

NY Times: U.S. alters rule on paying for end-of-life planning

The Obama administration, reversing course, will revise a Medicare regulation to delete references to end-of-life planning as part of the annual physical examinations covered under the new health care law, administration officials said Tuesday (Robert Pear, 1/4).

6 Jan 2011

J&JPRD submits New Drug Application to FDA for rivaroxaban

Johnson & Johnson Pharmaceutical Research & Development, L.L.C. announced today that it has submitted a New Drug Application to the U.S. Food and Drug Administration for rivaroxaban, an investigational, oral, once-daily anticoagulant, for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation.

6 Jan 2011

JAX, Tufts University unveil new mammalian genetics track for PhD students

The Jackson Laboratory, Sackler School of Graduate Biomedical Sciences at Tufts, and Tufts University School of Medicine have unveiled a new mammalian genetics track for PhD students. The joint track offers students in-depth research and training at both JAX and Tufts.

6 Jan 2011

Punch card study reveals link between high-density lipoprotein particles and heart disease

A stack of punch cards from a landmark study published in 1966, and the legwork to track down the study's participants years later, has yielded the longest analysis of the effects of lipoproteins on coronary heart disease.

6 Jan 2011

Studded tires can cause damage to public health and pavement

Scientists are reporting new evidence on how studded tires - wintertime fixtures in some areas but banned in others for causing damage to pavement - may also damage the health of motorists and people living near highways.

6 Jan 2011

Indian drugmaker seeks to make, sell generic version of Pfizer's HIV drug

The Indian drugmaker Natco Pharma "said Wednesday it has informed Pfizer Inc. that it wants to make and sell a low-cost generic version of the U.S. company's [drug] maraviroc for treating the HIV infection under a so-called 'compulsory license'," Dow Jones Newswires/Smart Money reports.

6 Jan 2011

Mutated TDP-43 can cause neurons to die: Study

Lou Gehrig's disease, or amyotrophic lateral sclerosis, and frontotemporal lobar degeneration are characterized by protein clumps in brain and spinal-cord cells that include an RNA-binding protein called TDP-43. This protein is the major building block of the lesions formed by these clumps.

6 Jan 2011

Sanofi-aventis announces publication of positive BSI-201 phase II results for breast cancer

Sanofi-aventis and its wholly-owned subsidiary, BiPar Sciences, today announced that The New England Journal of Medicine published the final phase II data for the investigational drug iniparib demonstrating significant clinical benefit in women with metastatic triple negative breast cancer when iniparib was administered in combination with chemotherapy agents gemcitabine/carboplatin.

6 Jan 2011

Scientists identify prognostic biomarker to treat patients with HCV

Scientists at Inserm and Institut Pasteur have performed biomarker discovery on patients being treated for chronic hepatitis C infection. Their work, published in The Journal of Clinical Investigation, demonstrates that the plasma levels of the protein IP-10 predict, prior to treatment initiation, the efficacy of treatment with pegylated-interferon and ribavirin.

6 Jan 2011

Research says regular intake of green tea can prevent Alzheimer's disease

Regularly drinking green tea could protect the brain against developing Alzheimer's and other forms of dementia, according to latest research by scientists at Newcastle University.

6 Jan 2011

States continue implementation efforts; Some newly-elected AGs step up legal attacks

Even as health overhaul drama continues on Capitol Hill, news outlets continue to watch how developments at the state level will impact the law's implementation.

6 Jan 2011

Regular eye exams are critical to prevent glaucoma

Glaucoma is the second leading cause of blindness, may strike without symptoms, is not preventable, but it is treatable. During National Glaucoma Awareness Month, The Minnesota Optometric Association (MOA) urges regular eye exams because early detection and treatment is critical to maintain healthy vision and protect the eyes from the effects of glaucoma and other potentially blinding diseases.

6 Jan 2011

Columbia research team identifies bacteria may play a key role in atherosclerosis

Dr. Emil Kozarov and a team of researchers at the Columbia University College of Dental Medicine have identified specific bacteria that may have a key role in vascular pathogenesis, specifically atherosclerosis, or what is commonly referred to as "hardening of the arteries" - the number one cause of death in the United States.

6 Jan 2011

Positive topline results from ZGN-433 Phase 1b study in obesity patients

Zafgen, a pharmaceutical company pioneering novel obesity therapeutics to help the body regain and sustain a lean, healthy state by targeting imbalances in fat metabolism, today announced positive topline results from its Phase 1b study of ZGN-433, a methionine aminopeptidase 2 inhibitor, for the treatment of severe obesity.

6 Jan 2011

Study shows positive effects of formal child care in improving language skills

Fewer children who attend regular formal centre- and family-based child care at 1.5 years and 3 years of age were late talkers compared with children who are looked after at home by a parent, child-carer or in an outdoor nursery. This is shown in a new study by the Norwegian Institute of Public Health of nearly 20,000 children.

6 Jan 2011

IV fluids for trauma patients may not be life savers all the time

Severely injured patients who are routinely given IV fluids by paramedics before transport to the nearest trauma center are significantly more likely to die than similarly injured patients who don't get the time-consuming IV treatment before hospitalization, new Johns Hopkins-led research suggests.

6 Jan 2011