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Top-line results of TIGER-2 Phase 3 clinical trial for CF treatment

Inspire Pharmaceuticals, Inc. announced today the top-line results from its second Phase 3 clinical trial, TIGER-2, with denufosol tetrasodium for the treatment of cystic fibrosis.

3 Jan 2011

Ecron Acunova, Newcastle University sign Memorandum of Understanding for clinical research

Ecron Acunova and Newcastle University have signed a Memorandum of Understanding signalling an intention by both parties to explore ways of working closely together in the area of clinical trials.

3 Jan 2011

Tips to prevent a hangover

Dr. Andrew Yacht, director of the division of general medicine and vice chair of medicine for education at Maimonides Medical Center in New York City said, “Alcohol clearly causes hangovers, but why it causes hangovers isn’t very well understood…Part of the suspected cause is dehydration and an electrolyte and hormonal imbalance. Some of the symptoms may be caused by low blood sugar. Or, it may be that the direct toxic effects of alcohol are causing the symptoms.”

2 Jan 2011

Canada’s anti-smoking warnings get larger

Canada will have larger and enhanced warning labels on cigarette packs, it was revealed in a government announcement last Thursday. Health Minister Leona Aglukkaq said that these new warnings will cover three-quarters of the front and back of cigarette packs, up from one-half.

2 Jan 2011

General anaesthesia brings reversible coma and not sleep: Study

Anaesthesia has been one of the greatest gifts of science and use of general anaesthesia is a routine part of surgical operations at hospitals and medical facilities around the world. However precise biological mechanisms of the drugs’ effects on the brain are only now being analyzed. In a review article published this week in the New England Journal of Medicine, scientists have tried to analyze a range of disciplines, including neuroscience and sleep medicine to understand how anaesthesia actually works.

2 Jan 2011

Home births on the decline in UK: Midwives protest

According to a leader of Britain’s midwives, more and more women are being discouraged from giving birth at home. Cathy Warwick, general secretary of the Royal College of Midwives said that many GPs are citing harms of a home birth like dangerous bleeding where their midwives may be unable to help. Warwick said, “There are doctors that still tell women scary things that aren’t evidence-based that then put them off having a home birth…

30 Dec 2010

Fungus may provide clue about human response to changes in circadian rhythm

Humans are not the only species ruled by a circadian rhythm. Even simple organisms like moulds are governed by an inner clock. Studying red bread mould may teach us how our own internal clock works. This is exactly what the Centre for Organelle Research at the University of Stavanger, Norway is doing.

30 Dec 2010

Adjusting mortality for reliability provides more stable estimates of hospital quality

New research published in the January issue of the Journal of Vascular Surgery® explores the impact that adjustments in statistical reliability can have on hospital quality rankings for vascular surgery. A total of 14,569 patients who underwent common vascular procedures (open and endovascular abdominal aortic aneurysm repair, carotid endarterectomy, lower extremity bypass and aorto-femoral bypass) were identified through the 2007 National Surgical Quality Improvement Project (NSQIP).

30 Dec 2010

Sleep-deprived physicians not to perform elective surgeries without patient's consent

While regulations have been put in place to restrict the work hours of doctors in training, no such regulations exist for fully trained physicians. An editorial in this week's New England Journal of Medicine argues that sleep-deprived physicians should not be permitted to proceed with an elective surgery without a patient's informed, written consent.

30 Dec 2010

How parents gauge level of ear pain in preverbal children

Levels of pain severity from ear aches observed and reported by parents of preverbal children can be influenced as much by socioeconomic status and other non-clinical factors as symptoms unless physicians ask about specific observable symptoms, according to research in The Journal of Pain, published by the American Pain Society.

30 Dec 2010

Two out of three children experience cyber-bullying

Two out of three children have experienced bullying via the Internet or mobile phones according to a survey made by Telenor in 2008 in Norway. The survey also shows that parents are uncertain about what to do about this kind of bullying.

30 Dec 2010

Low levels of microbe-killing molecules improve survival rate of people with CGD

Investigators at the National Institutes of Health have observed that the survival rate of people with a rare immunodeficiency disease called chronic granulomatous disease is greatly improved when even very low levels of microbe-killing molecules are present.

30 Dec 2010

Interaction of light with circadian systems

In a new paper published this week in the Proceedings of the National Academy of Sciences, Aziz Sancar, MD, PhD, the Sarah Graham Kenan Professor of Biochemistry and Biophysics in the UNC School of Medicine, and his colleagues have taken an important step in understanding the underlying molecular signals that influence a broad array of biological processes ranging from the sleep-wake cycle to cancer growth and development.

30 Dec 2010

Researchers study molecular mechanisms in early stages of IPN virus infection

Infectious pancreatic necrosis is a serious disease that leads to enormous losses in the salmon industry each year. The virus that causes the disease, IPN, is very prevalent in farmed salmon and trout in Norway. The virus attacks a wide diversity of hosts and has been found to occur in many different fish species, in addition to shellfish and molluscs.

30 Dec 2010

Indoor plants can contribute to patient well-being

Could a plant "intervention" improve the well-being of patients in a difficult rehab process? Scientists from the Norwegian University of Life Sciences and Sweden's Uppsala University investigated this question in a recent study of 436 coronary and pulmonary patients at a Norwegian rehabilitation center.

30 Dec 2010

Omega-3 fatty acids may reduce inflammation, disease symptoms and cartilage degeneration

Omega-3 fatty acids from seafood may reduce inflammation, symptoms of gum disease and risk of abnormal heartbeats early after cardiac surgery. One type of omega-3, DHA (docosahexaenoic acid), may also have lasting benefits in visual function for years in children whose mothers consume sufficient prenatal DHA.

30 Dec 2010

Researchers to identify gene variants that cause ischemic stroke

Researchers from the University of Maryland School of Medicine are coordinating an international team of scientists working to identify genes or gene variants that may make a person more likely to have a particular type of stroke called an ischemic stroke.

30 Dec 2010

Intellipharmaceutics granted extension of deadline to regain compliance with Nasdaq Listing Rule

Intellipharmaceutics International Inc., a pharmaceutical company specializing in the research, development and manufacture of novel or generic controlled release and targeted release oral solid dosage drugs, today announced that the staff of the Nasdaq Stock Market has granted the Company an extension of the deadline to regain compliance with Nasdaq Listing Rule 5550(b).

30 Dec 2010

New study confirms pancreas disease infects horizontally from population to population in seawater phase

Researchers and the salmon industry have been debating whether fingerling from freshwater farms can be a source of the virus that causes pancreas disease: salmonid alfavirus. The results of a new doctoral study show that this is not the case: pancreas disease transmits horizontally in the seawater phase and infection in fresh water has little bearing on how the disease spreads.

29 Dec 2010

Centocor Ortho Biotech files REMICADE sBLA for ulcerative colitis in pediatric patients

Centocor Ortho Biotech Inc. announced today that it has filed a supplemental Biologics License Application (sBLA) with the U.S. Food and Drug Administration (FDA) requesting the approval of REMICADE® (infliximab) for the treatment of moderately to severely active ulcerative colitis (UC) in pediatric patients who have had an inadequate response to conventional therapy.

29 Dec 2010

Research News and Research

Top-line results of TIGER-2 Phase 3 clinical trial for CF treatment

Ecron Acunova, Newcastle University sign Memorandum of Understanding for clinical research

Tips to prevent a hangover

Canada’s anti-smoking warnings get larger

General anaesthesia brings reversible coma and not sleep: Study

Home births on the decline in UK: Midwives protest

Fungus may provide clue about human response to changes in circadian rhythm

Adjusting mortality for reliability provides more stable estimates of hospital quality

Sleep-deprived physicians not to perform elective surgeries without patient's consent

How parents gauge level of ear pain in preverbal children

Two out of three children experience cyber-bullying

Low levels of microbe-killing molecules improve survival rate of people with CGD

Interaction of light with circadian systems

Researchers study molecular mechanisms in early stages of IPN virus infection

Indoor plants can contribute to patient well-being

Omega-3 fatty acids may reduce inflammation, disease symptoms and cartilage degeneration

Researchers to identify gene variants that cause ischemic stroke

Intellipharmaceutics granted extension of deadline to regain compliance with Nasdaq Listing Rule

New study confirms pancreas disease infects horizontally from population to population in seawater phase

Centocor Ortho Biotech files REMICADE sBLA for ulcerative colitis in pediatric patients

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