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Exploring molecular docking and molecular dynamics simulations as advanced tools for novel antiviral drug discovery

Researchers presented an overview of factors influencing emerging infectious diseases. They also highlighted the importance of molecular dynamic (MD) simulations and molecular docking (MDO) analysis for combating these diseases.

17 Oct 2022

Selective immunoglobulin A deficiency a risk factor for severe COVID-19

In a recent study published in The Journal of Allergy and Clinical Immunology, researchers in New Zealand gathered evidence to show that selective immunoglobulin A deficiency (sIgAD) is an understated risk factor for severe coronavirus disease 2019 (COVID-19).

17 Oct 2022

Inhalation therapeutics against COVID-19

A recent study published in the Pulmonary Pharmacology & Therapeutics journal described different inhalation therapeutic agents for treating respiratory viral infections like coronavirus disease 2019 (COVID-19).

17 Oct 2022

SARS-CoV-2 envelope structural protein found to form voltage-activated and calcium-activated calcium channels

In a new study, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium cations (Ca2+) cations.

14 Oct 2022

International group of honorees to provide latest insights into preventing and treating obesity

An international group of honorees have been selected to present innovative research designs providing the latest insights into preventing and treating obesity during the 10th annual Obesity Journal Symposium.

14 Oct 2022

UNO-peptide-modified CCN shows promise for targeted delivery of TAM immunomodulatory agents

Announcing a new publication for Acta Materia Medica journal. Tumor-associated macrophages (TAMs) are key contributors to tumor development, accelerated tumor invasion and metastasis, and induction of immunosuppression.

13 Oct 2022

The impact of humidity levels on viral transmission and viability

A recent PLoS ONE study reviewed the impact of humidity on virus transmission and its viability.

13 Oct 2022

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

A new study aimed to analyze the immunometalobism BALF cells from mild to severe COVID-19 patients using computational algorithms that quantified metabolic fluxes and metabolic pathways.

13 Oct 2022

New method allows for a much more detailed examination of the brain processes

Scientists have developed a research method that allows for a much more detailed examination of the brain processes involved in some neurological and mental disorders.

12 Oct 2022

Research shows how a very low dose of rhenium metal complex kills ovarian cancer cells

Metal-containing complexes have taken up center stage in the search for new cancer drugs that are as free of side effects as possible.

12 Oct 2022

The ability of antiviral formulation ViruSAL to inhibit SARS-CoV-2 infectivity

Researchers from Ireland used human bronchial epithelium models to evaluate the ability of a novel proprietary formulation called ViruSAL to inhibit SARS-CoV-2 infections.

12 Oct 2022

Precise DNA cleavage using new CRISPR-Cas approach

A team led by investigators at Massachusetts General Hospital (MGH) has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies.

11 Oct 2022

Neuropilin 2 identified as a novel regulator of distal colonic smooth muscle motility

Colonic motility disorders, especially problems associated with constipation and diarrhea, are common in adults and children, greatly impacting quality of life.

11 Oct 2022

Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

In a new study, researchers pursued direct-acting severe acute respiratory syndrome coronavirus-2 drugs that compete for nucleotide-binding pockets (NBPs) of SARS-CoV-2 proteins.

11 Oct 2022

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

A new paper reviews current knowledge of RdRp inhibitors that could be developed further to provide broadly effective antivirals against SARS-CoV-2 in particular and CoVs in general.

10 Oct 2022

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

Researchers examined the replicative capacity of seven SARS-CoV-2 isolates in 17 cell lines to understand their phenotypic variations and host range.

7 Oct 2022

USF researchers test a protein that shows potential as novel therapeutic for ALS patients

Researchers at the USF Health Morsani College of Medicine, located at the University of South Florida, successfully tested a protein that has the potential to aid in the development of a protein-based therapy for patients with ALS, a progressive nervous system disease, also known as Lou Gehrig's disease, that affects nerve cells in the brain and spinal cord.

7 Oct 2022

What is the impact of monkeypox infection on the hemostatic system?

In a recent study, researchers determined if monkeypox (MPX) infection affected the hemostatic system like that observed in coronavirus disease 2019 (COVID-19).

6 Oct 2022

The neuroprotective potential of Cannabis sativa L. against Alzheimer's disease

A recent study assesses the neuroprotective potential of the active constituents of cannabis in treating dementia and Alzheimer's disease.

6 Oct 2022

PerkinElmer’s Oxford Immunotec receives U.S. FDA approval for T-cell select to automate clinically superior tuberculosis detection

PerkinElmer’s (NYSE: PKI) Oxford Immunotec today announced the U.S. Food and Drug Administration (FDA) has approved the use of the T-Cell Select™ reagent kit for the automation of its T-SPOT®.TB test workflow for in vitro diagnostic (IVD) use by certified laboratories.

From Oxford Immunotec 6 Oct 2022

in vitro News and Research

Exploring molecular docking and molecular dynamics simulations as advanced tools for novel antiviral drug discovery

Selective immunoglobulin A deficiency a risk factor for severe COVID-19

Inhalation therapeutics against COVID-19

SARS-CoV-2 envelope structural protein found to form voltage-activated and calcium-activated calcium channels

International group of honorees to provide latest insights into preventing and treating obesity

UNO-peptide-modified CCN shows promise for targeted delivery of TAM immunomodulatory agents

The impact of humidity levels on viral transmission and viability

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

New method allows for a much more detailed examination of the brain processes

Research shows how a very low dose of rhenium metal complex kills ovarian cancer cells

The ability of antiviral formulation ViruSAL to inhibit SARS-CoV-2 infectivity

Precise DNA cleavage using new CRISPR-Cas approach

Neuropilin 2 identified as a novel regulator of distal colonic smooth muscle motility

Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

USF researchers test a protein that shows potential as novel therapeutic for ALS patients

What is the impact of monkeypox infection on the hemostatic system?

The neuroprotective potential of Cannabis sativa L. against Alzheimer's disease

PerkinElmer’s Oxford Immunotec receives U.S. FDA approval for T-cell select to automate clinically superior tuberculosis detection

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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